Results 51 to 60 of about 3,489,473 (275)

Effect of Sinusoidal Surface Roughness and Energy on the Orientation of Cylinder-Forming Block Copolymer Thin Films

, 2018
We explore the relative stability of three possible orientations of cylinder-forming di-block copolymer on a sinusoidally corrugated substrate. The cylinders can be aligned either parallel to the substrate, with their long axis being oriented along or ...
Aissou, Karim, Andelman, David, Man, Xingkun, Zhu, Yanyan   +3 more
core   +3 more sources

A Study of Static and Dynamic Mechanical Behavior of the Substrate in Ultrasonic Consolidation [PDF]

, 2006
A new 2-D FEM model is developed for a fundamental study of the time dependent mechanical behavior of the substrate in ultrasonic consolidation. The simulation shows that for a given vibration condition, the amplitude of contact friction stress and ...
Li, Leijun, Zhang, Chunbo
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The Type and Concentration of Inoculum and Substrate as Well as the Presence of Oxygen Impact the Water Kefir Fermentation Process

Frontiers in Microbiology, 2021
Eleven series of water kefir fermentation processes differing in the presence of oxygen and the type and concentration of inoculum and substrate, were followed as a function of time to quantify the impact of these parameters on the kinetics of this ...
David Laureys, Frédéric Leroy, Tom Hauffman, Marc Raes, Maarten Aerts, Peter Vandamme, Luc De Vuyst   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

AGROTECHNOLOGУ OF SMALL-VOLUME AND NON-SOIL INTENSE LIGHT-CULTURE IN CUCUMBER

Овощи России, 2017
Technology  of  intense  light-culture   has  been  developed to grow different crops under controlled environmental conditions  with  the use of specialized vegetation  apparatus  (VSU). In  the  specialized  vegetation apparatus,  designed  to   grow  
L. M. Anikina, P. Y. Kononchuk, V. L. Sudakov, O. R. Udalova, Y. V. Khomyakov   +4 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Deep learning framework for vertebral heart size and cardiothoracic ratio estimation in dogs and cats using thoracic radiographs

Frontiers in Veterinary Science
IntroductionHeart disease is a major cause of mortality in aging dogs and cats, with cardiomegaly being the most frequent radiographic finding. While deep learning methods have shown potential in detecting and quantifying cardiomegaly, their integration ...
Habtamu Tilahun Mekonnen, Núria Puig, Alejandro Elson, Elena López, Paula Martínez, Selene Campos, Francisco Hernández, Daniel Mayor, Jorge Quilis, Xavier Cufí, Jordi Freixenet, Arnau Oliver, Xavier Lladó, Robert Martí   +13 more
doaj   +1 more source