Results 181 to 190 of about 810,832 (336)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Experimental and In Silico Approaches to Study Carboxylesterase Substrate Specificity. [PDF]

J Xenobiot
Ribone SR, Quevedo MA.
europepmc   +1 more source

Characterization and Potential Application of Substrate-Specific Recognition by the Yeast Ubiquitin Ligase Rsp5: To Prevent Ubiquitin “Missending”

, 2018
Daisuke Watanabe, Hiroshi Takagi
openalex   +2 more sources

FCS of Mutated Phosphatidylinositol-specific Phospholipase C Enzymes Monitors the Interplay of Substrate and Activator Lipid Binding [PDF]

, 2009
Mingming Pu, Mary F. Roberts, Anne Gershenson   +2 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Diversity of FAAL enzymes and prediction of their substrate specificity using FAALPred. [PDF]

Protein Sci
Liong A, Pereira LM, Leão PN.
europepmc   +1 more source

SUBSTRATE SPECIFICITY OF BRAIN HEXOKINASE

Journal of Biological Chemistry, 1954
A, SOLS, R K, CRANE
openaire   +2 more sources

Highly Efficient Chemoenzymatic Synthesis of Naturally Occurring and Non‐Natural α‐2,6‐Linked Sialosides: A P. damsela α‐2,6‐Sialyltransferase with Extremely Flexible Donor–Substrate Specificity

, 2006
Hai Yu, Shengshu Huang, Harshal A. Chokhawala, Mingchi Sun, Haojie Zheng, Xi Chen   +5 more
openalex   +1 more source

Characterization of the Efflux Capability and Substrate Specificity of Aspergillus fumigatus PDR5-like ABC Transporters Expressed in Saccharomyces cerevisiae

, 2020
Brooke D. Esquivel, Jeffrey M. Rybak, Katherine S. Barker, Jarrod R. Fortwendel, P. David Rogers, Theodore C. White   +5 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source