Results 21 to 30 of about 494,088 (314)
The evolution of cyclodextrin glucanotransferase product specificity [PDF]
Cyclodextrin glucanotransferases (CGTases) have attracted major interest from industry due to their unique capacity of forming large quantities of cyclic α-(1,4)-linked oligosaccharides (cyclodextrins) from starch.
Dijkhuizen, Lubbert; id_orcid +9 more
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Understanding the underlying principles for crosstalk involving posttranslational modifications (PTMs) is of fundamental importance. In this article, we review some of previous results which indicated that pre-installed PTMs on nucleosome substrates (or ...
Hong, Guo, Ping, Qian
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Comparative Studies on Retroviral Proteases: Substrate Specificity
Exogenous retroviruses are subclassified into seven genera and include viruses that cause diseases in humans. The viral Gag and Gag-Pro-Pol polyproteins are processed by the retroviral protease in the last stage of replication and inhibitors of the HIV-1
József Tözsér
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Evolution of substrate specificity in the Nucleobase-Ascorbate Transporter (NAT) protein family [PDF]
L-ascorbic acid (vitamin C) is an essential metabolite in animals and plants due to its role as an enzyme co-factor and antioxidant activity. In most eukaryotic organisms, L-ascorbate is biosynthesized enzymatically, but in several major groups ...
Anezia Kourkoulou +2 more
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Substrate specificity of human MCPIP1 endoribonuclease
MCPIP1, also known as Regnase-1, is a ribonuclease crucial for regulation of stability of transcripts related to inflammatory processes. Here, we report that MCPIP1 acts as an endonuclease by degrading several stem-loop RNA structures and single-stranded
Mateusz Wilamowski +3 more
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Substrate Specificity of Recombinant Ser/Thr Protein Kinase
Protein kinases are enzymes that phosphorylate proteins in a cell. Determination of kinase activity in reactions of phosphorylation is a very convenient way for a biochemical characterization of this group of enzymes.
Anna Zorina, Galina Novikova, Dmitry Los
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Diverse physiological functions for dual-specificity MAP kinase phosphatases [PDF]
A structurally distinct subfamily of ten dual-specificity (Thr/Tyr) protein phosphatases is responsible for the regulated dephosphorylation and inactivation of mitogen-activated protein kinase (MAPK) family members in mammals.
Keyse, Stephen M, Dickinson, Robin J
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Crystal Structure and Substrate Specificity of PTPN12
PTPN12 is an important tumor suppressor that plays critical roles in various physiological processes. However, the molecular basis underlying the substrate specificity of PTPN12 remains uncertain.
Hui Li +18 more
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The substrate specificity of phospholipase A
Investigations on variously modified analogues of phospholipids elucidated the following substrate characteristics for phospholipase A (Crotalus adamanteus). 1. 1. Within the class of α-phosphoglycerides l-isomers are readily hydrolysed, while d-α-phospholipids appeared not to be attacked. 2. 2.
Deenen, L.L.M. van, Haas, Gerard H. de
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YscP, a key player in the type three secretion system of "Yersinia enterocolitica" [PDF]
The Yersinia injectisome needle has a constant length of around 60nm. Mutants affected in the yscP gene display abnormally long needles, suggesting that needle length is genetically controlled and that YscP is involved in this process. First, both N- and
Agrain, Céline
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