Results 21 to 30 of about 797,048 (304)
Predicting the substrate specificity of a glycosyltransferase implicated in the production of phenolic volatiles in tomato fruit [PDF]
The volatile compounds that constitute the fruit aroma of ripe tomato (Solanum lycopersicum) are often sequestered in glycosylated form. A homology-based screen was used to identify the gene SlUGT5, which is a member of UDP-glycosyltransferase 72 family ...
Alba +41 more
core +2 more sources
Substrate specificity of human MCPIP1 endoribonuclease
MCPIP1, also known as Regnase-1, is a ribonuclease crucial for regulation of stability of transcripts related to inflammatory processes. Here, we report that MCPIP1 acts as an endonuclease by degrading several stem-loop RNA structures and single-stranded
Mateusz Wilamowski +3 more
doaj +1 more source
Substrate Specificity of Recombinant Ser/Thr Protein Kinase
Protein kinases are enzymes that phosphorylate proteins in a cell. Determination of kinase activity in reactions of phosphorylation is a very convenient way for a biochemical characterization of this group of enzymes.
Anna Zorina, Galina Novikova, Dmitry Los
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Evolution of substrate specificity in a retained enzyme driven by gene loss. [PDF]
The connection between gene loss and the functional adaptation of retained proteins is still poorly understood. We apply phylogenomics and metabolic modeling to detect bacterial species that are evolving by gene loss, with the finding that ...
Babnigg, Gyorgy +14 more
core +1 more source
Crystal Structure and Substrate Specificity of PTPN12
PTPN12 is an important tumor suppressor that plays critical roles in various physiological processes. However, the molecular basis underlying the substrate specificity of PTPN12 remains uncertain.
Hui Li +18 more
doaj +1 more source
Substrate Specificity of Chlorophyllase [PDF]
Apparent Km and V(max) values were obtained for hydrolysis of methyl and ethyl chlorophyllides a, methyl and ethyl pheophorbide a, and 9-hydroxymethyl pheophorbide a by chlorophyllase from Ailanthus altissima. Analysis of substrate specificity data for chlorophyllase indicates that the presence of a 9-keto group and a methyl alcohol group esterified at
openaire +2 more sources
On the substrate specificity of human CYP27A1
The mitochondrial sterol 27-hydroxylase (CYP27A1) is required for degradation of the C27-sterol side chain in bile acid biosynthesis. CYP27A1 seems, however, to have roles beyond this, as illustrated by patients with a deficient sterol 27-hydroxylase due
Maria Norlin +3 more
doaj +1 more source
Phosphotyrosine Substrate Sequence Motifs for Dual Specificity Phosphatases. [PDF]
Protein tyrosine phosphatases dephosphorylate tyrosine residues of proteins, whereas, dual specificity phosphatases (DUSPs) are a subgroup of protein tyrosine phosphatases that dephosphorylate not only Tyr(P) residue, but also the Ser(P) and Thr(P ...
Bryan M Zhao +8 more
doaj +1 more source
Substrate specificity is a hallmark of enzymatic catalysis. In this work, the biomimetic catalytic oxidation of styrene and cyclohexanone by iron (III) porphyrins and molecular oxygen was carried out, and remarkable differences in efficiency were ...
Xian-Tai Zhou, Hong-Bing Ji
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Substrate specificity of Ty1 integrase [PDF]
Integration of the Saccharomyces cerevisiae retrotransposon Ty1 requires the element-encoded integrase (IN) protein, which is a component of cytoplasmic virus-like particles (VLPs). Using purified recombinant Ty1 IN and an oligonucleotide integration assay based on Ty1 long terminal repeat sequences, we have compared IN activity on substrates having ...
S P, Moore, M, Powers, D J, Garfinkel
openaire +2 more sources

