Elucidation of substrate specificity in Aspergillus nidulans UDP-galactose-4-epimerase. [PDF]
PLoS ONE, 2013 The frequency of invasive fungal infections has rapidly increased in recent years. Current clinical treatments are experiencing decreased potency due to severe host toxicity and the emergence of fungal drug resistance.
Sean A Dalrymple +4 more
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Isolation and characterisation of two chymotrypsins from Allocyttus niger (black oreo dory) viscera [PDF]
, 1997 Two serine proteases from the viscera of deep-sea fish, black oreo dory (Allocyttus niger),were purified by hydrophobic, affinity, and cation exchange chromatography.
Daniel, Roy M., Krzyzosiak, J.
core +2 more sources
Substrate Specificity of Chlorophyllase [PDF]
Plant Physiology, 1975 Apparent Km and V(max) values were obtained for hydrolysis of methyl and ethyl chlorophyllides a, methyl and ethyl pheophorbide a, and 9-hydroxymethyl pheophorbide a by chlorophyllase from Ailanthus altissima. Analysis of substrate specificity data for chlorophyllase indicates that the presence of a 9-keto group and a methyl alcohol group esterified at
openaire +3 more sources
Comparative Studies on Retroviral Proteases: Substrate Specificity
Viruses, 2010 Exogenous retroviruses are subclassified into seven genera and include viruses that cause diseases in humans. The viral Gag and Gag-Pro-Pol polyproteins are processed by the retroviral protease in the last stage of replication and inhibitors of the HIV-1
József Tözsér
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Identification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5R [PDF]
, 2000 Background: Vaccinia virus gene B1R encodes a erine/threonine protein kinase. In vitro this protein kinase phosphorylates ribosomal proteins Sa and S2 and vaccinia virus protein H5R, proteins that become phosphorylated during infection.
Beaud, G. +4 more
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Origin and evolution of transporter substrate specificity within the NPF family
eLife, 2017 Despite vast diversity in metabolites and the matching substrate specificity of their transporters, little is known about how evolution of transporter substrate specificities is linked to emergence of substrates via evolution of biosynthetic pathways ...
M. E. Jørgensen +9 more
semanticscholar +1 more source
Substrate Specificity of Recombinant Ser/Thr Protein Kinase
Bio-Protocol, 2015 Protein kinases are enzymes that phosphorylate proteins in a cell. Determination of kinase activity in reactions of phosphorylation is a very convenient way for a biochemical characterization of this group of enzymes.
Anna Zorina, Galina Novikova, Dmitry Los
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Predicting the substrate specificity of a glycosyltransferase implicated in the production of phenolic volatiles in tomato fruit [PDF]
, 2011 The volatile compounds that constitute the fruit aroma of ripe tomato (Solanum lycopersicum) are often sequestered in glycosylated form. A homology-based screen was used to identify the gene SlUGT5, which is a member of UDP-glycosyltransferase 72 family ...
Alba +41 more
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Substrate specificity of the ubiquitin and Ubl proteases
Cell Research, 2016 Conjugation and deconjugation of ubiquitin and ubiquitin-like proteins (Ubls) to cellular proteins are highly regulated processes integral to cellular homeostasis.
J. Ronau, J. Beckmann, M. Hochstrasser
semanticscholar +1 more source
Differential substrate specificity could be exploited [PDF]
, 2013 Abbreviations: H7 1-(5-isoquinoiine sulphonyl)-2-methylpiperazine dichloride K252b (8R∗; 9s∗; 11∗)-(−)-9-hydroxy-9-methoxycarbonyl-8-methyl-2; 3; 9; 10-tetra-hydro-8; 11-epoxy-1H; 8H; 11H-2; 7b; 11a-triazadibenzo(a; g)cydoocta(c; d; e)trindenl-one-9 ...
Boscá, Lisardo +2 more
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