Results 51 to 60 of about 810,832 (336)
Dna2 is a structure-specific nuclease, with affinity for 5'-flap intermediates [PDF]
, 2010 Dna2 is a nuclease/helicase with proposed roles in DNA replication, double-strand break repair and telomere maintenance. For each role Dna2 is proposed to process DNA substrates with a 5'-flap.
Aguilera +54 more
core +2 more sources
Current understanding of substrate specificity and regioselectivity of LPMOs
Bioresources and Bioprocessing, 2020 Renewable biomass such as cellulose and chitin are the most abundant sustainable sources of energy and materials. However, due to the low degradation efficiency of these recalcitrant substrates by conventional hydrolases, these biomass resources cannot ...
Xiaoli Zhou, Honghui Zhu
doaj +1 more source
Substrate specificity of amine oxidase [PDF]
, 1943 The tyramine oxidase activity of liver extracts found by Hare (1), the aliphatic amine oxidase activity of brain, kidney, and liver extracts observed by Pugh and Quastel (2), and the adrenalin oxidase activity of similar extracts noted by Blaschko ...
Alles, Gordon A., Heegaard, Erik V.
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Activation and substrate specificity of the human P4-ATPase ATP8B1
Nature Communications, 2023 Asymmetric distribution of phospholipids in eukaryotic membranes is essential for cell integrity, signaling pathways, and vesicular trafficking. P4-ATPases, also known as flippases, participate in creating and maintaining this asymmetry through active ...
Thibaud Dieudonné +9 more
doaj +1 more source
Specificity and Kinetics of Haloalkane Dehalogenase [PDF]
, 1996 Haloalkane dehalogenase converts halogenated alkanes to their corresponding alcohols. The active site is buried inside the protein and lined with hydrophobic residues. The reaction proceeds via a covalent substrate-enzyme complex.
Janssen, Dick B., +2 more
core +5 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
, 2019 Plants have various color pigments. Many plants have fruits and flowers of vivid colors such as orange, red, purple and blue. Anthocyanins with anthocyanidins as aglycone are one group of plant pigments.
古川, 一実 +3 more
core
Mutations of penicillin acylase residue B71 extend substrate specificity by decreasing steric constraints for substrate binding [PDF]
, 2003 Two mutant forms of penicillin acylase from Escherichia coli strains, selected using directed evolution for the ability to use glutaryl-L-leucine for growth [Forney, Wong and Ferber (1989) Appl. Environ. Microbiol.
Brannigan, J A +5 more
core +2 more sources
The Substrate Specificity of Fumarase
Journal of Biological Chemistry, 1968 Abstract The substrate specificity of fumarase has been studied by measuring the ability of the enzyme to hydrate or dehydrate derivatives of fumarate and l-malate. Fumarase was observed to hydrate fumarate and its derivatives in the order, fluorofumarate g fumarate g chlorofumarate g bromofumarate g acetylenedicarboxylate g iodofumarate g mesaconate ...
J W, Teipel, G M, Hass, R L, Hill
openaire +2 more sources