Results 81 to 90 of about 12,106 (297)
Classical component mode synthesis methods for reduction are usually limited by the size and compatibility of the coupling interfaces. A component mode synthesis approach with constrained coupling interfaces is presented for vibro-acoustic modelling. The
Eskil Lindberg +2 more
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Identification of the Dynamic Properties of Linear Joints Using Substructure Synthesis Method
In this thesis, a new identification method for joint stiffness and damping has been developed by using the substructure synthesis method and finite element modeling. The substructure synthesis method is stated firstly, according to the substructures are
Tie Neng Guo +3 more
core +1 more source
Synthesis of (–)-Kopsifoline A and (+)-Kopsifoline E
We report the first total synthesis of (–)-kopsifoline A and (+)-kopsifoline E. Our synthetic strategy features a biogenetically inspired regioselective C17-functionalization of a versatile intermediate containing the pentacyclic core of aspidosperma ...
Mohammad, Movassaghi +2 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
High-pressure synthesis, mechanical properties, and magnetic behavior of chromium diboride
Despite persistent synthetic challenges in realizing borophene, transition metal diborides, characterized by honeycomb borophene substructure and weak interlayer coupling, are attracting growing interest as potentially viable alternatives.
Hao Jiang +4 more
doaj +1 more source
A substructure synthesis formulation for vibration isolation
The new modeling method presented here is classified as a substructure synthesis (SS) technique. The distinction between the new SS method and the component mode synthesis formulation is that no transformation between local coordinates and generalized ...
Pokines, Brett J.
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Trimeric lignin model compounds containing biphenyl (5-5') and beta-aryl ether (beta-O-4') were synthesized from dehydrodivanillin derivatives and alpha-bromo acetovanillone derivatives via Williamson's reaction. The ¹H and 13C NMR characteristics of the
Alves Vera L. +4 more
doaj
Causal Mechanism-Based Molecular Property Prediction [PDF]
In the field of quantum chemistry, molecular property prediction is a fundamental and critical task, which is widely used in many fields such as drug discovery and chemical synthesis prediction.
CAI Ruichu, XU Zunhong, CHEN Daoxin, YANG Zhenhui, LI Zijian, HAO Zhifeng
doaj +1 more source

