Results 91 to 100 of about 502,362 (345)

Existing motor state is favored at the expense of new movement during 13-35 Hz oscillatory synchrony in the human corticospinal system [PDF]

, 2005
Oscillations in local field potentials in the β-frequency band (13-35 Hz) are a pervasive feature of human and nonhuman primate motor cortical areas. However, the function of such synchronous activity across populations of neurons remains unknown.
B, B, Di, L, Doyle, L, Gilbertson, T, Lalo, E, P, ., V, C   +6 more
core  

Deep brain stimulation of the subthalamic nucleus modulates sensitivity to decision outcome value in Parkinson's disease. [PDF]

, 2016
Deep brain stimulation (DBS) of the subthalamic nucleus in Parkinson's disease is known to cause a subtle but important adverse impact on behaviour, with impulsivity its most widely reported manifestation.
,, Barbe, M, Dayan, P, Dolan, R, Fink, GR, Seymour, B, Shiner, T   +6 more
core   +3 more sources

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Motor Evoked Potentials Improve Targeting in Deep Brain Stimulation Surgery

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives One of the main challenges posed by the surgical deep brain stimulation (DBS) procedure is the successful targeting of the structures of interest and avoidance of side effects, especially in asleep surgery. Here, intraoperative motor evoked potentials (MEPs) might serve as tool to identify the pyramidal tract.
Petyo Nikolov, Verena Heil, Christian J. Hartmann, Nikola Ivanov, Philipp J. Slotty, Jan Vesper, Alfons Schnitzler, Stefan Jun Groiss   +7 more
wiley   +1 more source

Morphological changes of glutamatergic synapses in animal models of Parkinson’s disease

Frontiers in Neuroanatomy, 2015
The striatum and the subthalamic nucleus are the main entry doors for extrinsic inputs to reach the basal ganglia circuitry. The cerebral cortex, thalamus and brainstem are the key sources of glutamatergic inputs to these nuclei.
Rosa M Villalba, Rosa M Villalba, Abraham eMathai, Abraham eMathai, Yoland eSmith, Yoland eSmith, Yoland eSmith   +6 more
doaj   +1 more source

Cortical and Subcortical Contributions to Stop Signal Response Inhibition: Role of the Subthalamic Nucleus

Journal of Neuroscience, 2006
Suppressing an already initiated manual response depends critically on the right inferior frontal cortex (IFC), yet it is unclear how this inhibitory function is implemented in the motor system.
A. Aron, R. Poldrack
semanticscholar   +1 more source

Inference with interference between units in an fMRI experiment of motor inhibition

, 2017
An experimental unit is an opportunity to randomly apply or withhold a treatment. There is interference between units if the application of the treatment to one unit may also affect other units.
Aron A. R., Chiang-Shan R. Li, Cochran W. G., Conover W. J., Cox D. R., David O., Deshpande J. V., Duann J. R., Dylan S. Small, Fisher R. A., Forstmann B. U., Friston K. J., Friston K. J., Hoeffding W., Hudgens M. G., Lehmann E. L., Lehmann E. L., Li C. S., Lindquist M. A., Lindquist M. A., Lindquist M. A., Neyman J., Neyman J., Neyman J., Orban J., Paul R. Rosenbaum, Puri M. L., Rosenbaum P. R., Rosenbaum P. R., Rosenbaum P. R., Rosenbaum P. R., Rosenbaum P. R., Rubin D. B., Salsburg D. S., Simmonds D. J., Sobel M. E., Stephenson W. R., Stephenson W. R., Tukey J. W., Weiss L., Welch B. L., Xi Luo   +41 more
core   +1 more source

Dopamine-dependent scaling of subthalamic gamma bursts with movement velocity in patients with Parkinson’s disease [PDF]

, 2018
Gamma synchronization increases during movement and scales with kinematic parameters. Here, disease-specific characteristics of this synchronization and the dopamine-dependence of its scaling in Parkinson’s disease are investigated.
Bock, Antje, Horn, Andreas, Huebl, Julius, Krauss, Joachim K., Kühn, Andrea A., Lofredi, Roxanne, Neumann, Wolf-Julian, Schneider, Gerd-Helge, Siegert, Sandy   +8 more
core   +1 more source

Epilepsy surgery: From bench to the clinics

Epilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

Directional Deep Brain Stimulation for Parkinson's Disease: Results of an International Crossover Study With Randomized, Double‐Blind Primary Endpoint

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective Published reports on directional deep brain stimulation (DBS) have been limited to small, single‐center investigations. Therapeutic window (TW) is used to describe the range of stimulation amplitudes achieving symptom relief without side effects.
Alfons Schnitzler, Pablo Mir, Matthew A. Brodsky, Leonard Verhagen, Sergiu Groppa, Ramiro Alvarez, Andrew Evans, Marta Blazquez, Sean Nagel, Julie G. Pilitsis, Monika Pötter‐Nerger, Winona Tse, Leonardo Almeida, Nestor Tomycz, Joohi Jimenez‐Shahed, Witold Libionka, Fatima Carrillo, Christian J. Hartmann, Stefan Jun Groiss, Martin Glaser, Florence Defresne, Edward Karst, Binith Cheeran, Jan Vesper, for the PROGRESS Study Investigators   +24 more
wiley   +1 more source