Results 121 to 130 of about 502,362 (345)

Cognitive Outcome After Deep Brain Stimulation for Refractory Obsessive–Compulsive Disorder: A Systematic Review

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Introduction Deep brain stimulation (DBS) is an effective treatment for refractory obsessive–compulsive disorder (OCD). Neuropsychological assessment contributes to DBS treatment in several ways: it monitors the cognitive safety of the treatment, identifies beneficial or detrimental cognitive side effects and it could aid to explain ...
Tim A. M. Bouwens van der Vlis, Annelien Duits, Mégan M. G. H. van de Veerdonk, Anne E. P. Mulders, Koen R. J. Schruers, Yasin Temel, Linda Ackermans, Albert F. G. Leentjens   +7 more
wiley   +1 more source

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn, Jee‐Young Lee, Giorgia Sciacca, Stacy Patterson, Adam Morton, Paul Pun, Walaa A. Kamel, Marina Picillo, Bart Post, Eng‐King Tan, Tamine Capato, Bastiaan R. Bloem, Manon Auffret, Annelien M. Oosterbaan, Willanka Kapelle, Michiko K. Bruno, Lorraine V. Kalia, Jeffrey H. Kordower, Daniela Berg   +18 more
wiley   +1 more source

Adaptive Deep Brain Stimulation Benefits: Younger Patients with Persistent Wearing‐off Symptoms

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) often involves motor fluctuations and dyskinesia, which are difficult to manage with medication alone. Conventional deep brain stimulation (cDBS) effectively alleviates symptoms but has limitations, including the challenge of balancing therapeutic effects against potential side effects, as well as limited ...
Takuto Emura, Naoki Tani, Koichi Hosomi, Yuki Kimoto, Takahiro Matsuhashi, Takahiro Fujinaga, Shimpei Miura, Yuya Fujita, Nobuhiko Mori, Hui Ming Khoo, Satoru Oshino, Haruhiko Kishima   +11 more
wiley   +1 more source

Quantifying local field potential dynamics with amplitude and frequency stability between ON and OFF medication and stimulation in Parkinson's disease

Neurobiology of Disease
Neural oscillations are critical to understanding the synchronisation of neural activities and their relevance to neurological disorders. For instance, the amplitude of beta oscillations in the subthalamic nucleus has gained extensive attention, as it ...
Xuanjun Guo, Shenghong He, Xinyi Geng, Pan Yao, Christoph Wiest, Yingnan Nie, Huiling Tan, Shouyan Wang   +7 more
doaj   +1 more source

Dyskinesias and the subthalamic nucleus.

Annals of neurology, 2000
Severe dyskinesias or ballism can occur following hemorrhagic events in the subthalamic nucleus (STN), and it has recently been established that the STN plays a major role in the pathophysiology of the motor dysfunction of Parkinson's disease (PD) and that STN inhibition improves parkinsonian dysfunction.
Benabid, A L, Benazzouz, A, Limousin, P, Koudsie, A, Krack, Paul, Piallat, B, Pollak, Pierre   +6 more
openaire   +2 more sources

Modeling effect of GABAergic current in a basal ganglia computational model

, 2012
Electrical high frequency stimulation (HFS) of deep brain regions is a method shown to be clinically effective in different types of movement and neurological disorders.
Claussen, Jens Christian, Hofmann, Ulrich G., Moser, Andreas, Njap, Felix   +3 more
core   +1 more source

Desynchronizing effect of high-frequency stimulation in a generic cortical network model

, 2012
Transcranial Electrical Stimulation (TCES) and Deep Brain Stimulation (DBS) are two different applications of electrical current to the brain used in different areas of medicine. Both have a similar frequency dependence of their efficiency, with the most
A Antal, A Antal, A Benabid, A Compte, A Gupta, A Limoge, A Limoge, A Sances Jr, AS Pikovsky, B Nuttin, C Börgers, CC McIntyre, E Schöll, EM Izhikevich, EM Izhikevich, EM Izhikevich, EM Izhikevich, F Velasco, H Markram, J Lian, J Yianni, JA Acebrón, JA Obesó, JD Geyer, Jens Christian Claussen, JL Houeto, KJ Ressler, L Gang, L Garcia, M Steriade, Markus Schütt, P Coubes, R Kumar, R Wang, SC Bellinger, TR Anderson, V Visser-Vandewalle, X Zhang, Y Liu, Y Su   +39 more
core   +1 more source

Motor and Cognitive Outcome After Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson's Disease Harboring GBA1 Variant

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation (DBS) is effective for Parkinson's disease (PD); however, its efficacy varies with genetic background, such as the GBA1 variant—the causative gene of Gaucher disease—associated with increased PD risk and cognitive decline after subthalamic nucleus (STN)‐DBS.
Hikaru Kamo, Genko Oyama, Mai Shimizu, Haruka Takeshige‐Amano, Takashi Ogawa, Wataru Sako, Noriko Nishikawa, Taku Hatano, Yuanzhe Li, Hiroyo Yoshino, Manabu Funayama, Masanobu Ito, Hirokazu Iwamuro, Atsushi Umemura, Nobutaka Hattori   +14 more
wiley   +1 more source

Directional deep brain stimulation of the subthalamic nucleus: A pilot study using a novel neurostimulation device

Movement Disorders, 2016
A novel neurostimulation system allows steering current in horizontal directions by combining segmented leads and multiple independent current control.
F. Steigerwald, Lorenz Müller, S. Johannes, Cordula Matthies, J. Volkmann   +4 more
semanticscholar   +1 more source

Surgical Treatment of Tremor Syndromes: A Guide to the Clinician

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Tremor is a common feature of multiple neurological conditions, and while medications can be effective in mild cases, surgical interventions are often required in moderate–severe syndromes or when medication side‐effects are unacceptable.
James Peters, Joel Maamary, Yael Barnett, Andrea A. Kuhn, Benjamin Jonker, Stephen Tisch   +5 more
wiley   +1 more source