Results 121 to 130 of about 489,147 (319)

Frontal Cortex-Like Functions of the Subthalamic Nucleus [PDF]

Frontiers in Systems Neuroscience, 2011
The subthalamic nucleus (STN) has been considered a motor structure for a long time. Over the last 20 years, anatomical and behavioral data have highlighted the position of the STN within a prefrontal-associative and a limbic loops, suggesting that the STN should play a critical role in frontal functions such as attention, inhibitory control (including
Christelle Baunez, Christelle Baunez, Sylvie Lardeux, Sylvie Lardeux, Sylvie Lardeux   +4 more
openaire   +4 more sources

Effects of aging on nitrergic neurons in human striatum and subthalamic nucleus

Arquivos de Neuro-Psiquiatria, 2015
Nitric oxide (NO) is a major neurotransmitter associated with motor control in basal ganglia. Movement disorders, as essential tremor and Parkinson’s disease, are more prevalent on aged individuals.
Bruno Lopes dos Santos-Lobato, Elaine Aparecida Del-Bel, José Eymard Homem Pittella, Vitor Tumas   +3 more
doaj   +1 more source

Bilateral deep brain stimulation of the subthalamic nucleus in primary Meige syndrome.

Journal of Neurosurgery, 2017
OBJECTIVE Subthalamic nucleus deep brain stimulation has been shown to be effective in reducing symptoms of primary Meige syndrome. However, assessments of its efficacy and safety have been limited to several case reports and small studies.
Shikun Zhan, F. Sun, Yixin Pan, Wei Liu, Peng Huang, C. Cao, Jing Zhang, Dianyou Li, Bomin Sun   +8 more
semanticscholar   +1 more source

Long‐Term Quality of Life Trend after Subthalamic Stimulation for Parkinson's Disease: An Updated Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation of the subthalamic nucleus (STN‐DBS) is a well‐established treatment for Parkinson's Disease (PD). However, the long‐term trajectory of Quality of Life (QoL) following STN‐DBS remains underexplored. Objectives We aimed to conduct a systematic review and meta‐analysis to assess QoL trends up to five years after
Luis Otávio Nogueira, Angela Maria Sandini Corso, Louise Dalla Corte Dallé, Vanio L.J. Antunes, Matheus de M. Fernandes, Isabella S.M. Rabelo, Marcus V. Della Coletta, Carolina Candeias da Silva, Lorena Broseghini Barcelos, Henrique Ballalai Ferraz, Robson Luis Oliveira de Amorim, Dayany Leonel Boone   +11 more
wiley   +1 more source

Deep Brain Stimulation of Caudal Zona Incerta for Parkinson's Disease: One‐Year Follow‐Up and Electric Field Simulations

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective To evaluate the effects of bilateral caudal zona incerta (cZi) deep brain stimulation (DBS) for Parkinson's disease (PD) one year after surgery and to create anatomical improvement maps based on patient‐specific simulation of the electric field.
Rasmus Stenmark Persson, Teresa Nordin, Gun‐Marie Hariz, Karin Wårdell, Lars Forsgren, Marwan Hariz, Patric Blomstedt   +6 more
wiley   +1 more source

Subthalamic Nucleus Neurons Differentially Encode Early and Late Aspects of Speech Production

Journal of Neuroscience, 2017
Basal ganglia-thalamocortical loops mediate all motor behavior, yet little detail is known about the role of basal ganglia nuclei in speech production. Using intracranial recording during deep brain stimulation surgery in humans with Parkinson's disease,
W. Lipski, A. Alhourani, T. Pirnia, Peter W. Jones, C. Dastolfo-Hromack, Leah B. Helou, D. Crammond, S. Shaiman, M. Dickey, L. Holt, R. Turner, J. Fiez, R. Richardson   +12 more
semanticscholar   +1 more source

Local Field Potential‐Based Programming: A Proof‐of‐Concept Pilot Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Programming deep brain stimulation (DBS) is still based on a trial‐and‐error approach, often becoming a time‐consuming process for both treating physicians and patients. Several strategies have been proposed to streamline DBS programming, most of which are preliminary and mainly address Parkinson's disease, a condition readily ...
Alfonso Fasano, Carolina Gorodetsky, Darcia Paul, Jürgen Germann, Aaron Loh, Han Yan, Peter L. Carlen, Sara Breitbart, Andres M. Lozano, George M. Ibrahim, Suneil K. Kalia   +10 more
wiley   +1 more source

One-pass deep brain stimulation of dentato-rubro-thalamic tract and subthalamic nucleus for tremor-dominant or equivalent type Parkinson’s disease

Acta Neurochirurgica, 2016
BackgroundRefractory tremor in tremor-dominant (TD) or equivalent-type (EQT) idiopathic Parkinson’s syndrome (IPS) poses the challenge of choosing the best target region to for deep brain stimulation (DBS).
V. Coenen, M. Rijntjes, T. Prokop, T. Piroth, F. Amtage, H. Urbach, P. Reinacher   +6 more
semanticscholar   +1 more source

Speech Differences between Multiple System Atrophy and Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Delineation of Parkinson's disease (PD) from multiple system atrophy (MSA) can be challenging in early disease stages. Speech characteristics have been studied as digital biomarkers in PD and ataxias. Currently, data on speech in MSA is limited.
Tom Hähnel, Anna Nemitz, Katja Schön, Luise Berger, Annemarie Vogel, Doreen Gruber, Nils Schnalke, Stefan Bräuer, Björn H. Falkenburger, Florin Gandor   +9 more
wiley   +1 more source

Ultra-High Field MRI Post Mortem Structural Connectivity of the Human Subthalamic Nucleus, Substantia Nigra, and Globus Pallidus

Frontiers in Neuroanatomy, 2016
Introduction: The subthalamic nucleus, substantia nigra, and globus pallidus, three nuclei of the human basal ganglia, play an important role in motor, associative, and limbic processing.
B. Plantinga, A. Roebroeck, V. Kemper, K. Uludağ, Maartje Melse, J. Mai, M. Kuijf, A. Herrler, A. Jahanshahi, B. M. ter Haar Romeny, Y. Temel   +10 more
semanticscholar   +1 more source