Results 131 to 140 of about 489,147 (319)

Tics and Parkinson's Disease: Clinical and Pathophysiological Insights from a Rare Syndromic Association

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The coexistence of tics with Parkinson's disease (PD) is rare, as they often emerge at different ages, follow different trajectories and involve contrasting pathophysiological mechanisms related to dopamine availability and function in the brain. Cases We present 10 individuals with primary tic disorders who later developed PD.
Tarig Abkur, Alexandra Boogers, Talyta Grippe, David A. Isaacs, Irene A. Malaty, Renato P. Munhoz, Kailash P. Bhatia, Lauren A. Hart, Alfonso Fasano, Suneil Kalia, Anthony E. Lang, Christos Ganos   +11 more
wiley   +1 more source

Automatic target validation based on neuroscientific literature mining for tractography [PDF]

Front Neuroanat. 2015 May 27;9:66
Target identification for tractography studies requires solid anatomical knowledge validated by an extensive literature review across species for each seed structure to be studied. Manual literature review to identify targets for a given seed region is tedious and potentially subjective. Therefore, complementary approaches would be useful.
arxiv   +1 more source

Cortical and Subcortical Contributions to Stop Signal Response Inhibition: Role of the Subthalamic Nucleus

Journal of Neuroscience, 2006
Suppressing an already initiated manual response depends critically on the right inferior frontal cortex (IFC), yet it is unclear how this inhibitory function is implemented in the motor system.
A. Aron, R. Poldrack
semanticscholar   +1 more source

Acute Neuropsychiatric Decline in a Parkinson's Disease Patient with a Severe GBA1 Mutation Following Bilateral GPi Deep Brain Stimulation

Movement Disorders Clinical Practice, EarlyView.
Vijay G. Palakuzhy, Gian D. Pal, Mitra Afshari   +2 more
wiley   +1 more source

Transcranial Temporal Interference Stimulation of the Right Globus Pallidus in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Invasive deep brain stimulation (DBS) has been shown to be effective in treating patients with Parkinson's disease (PD), yet its clinical use is limited to patients at the advanced stage of the disease. Transcranial temporal interference stimulation (tTIS) may be a novel nonneurosurgical and safer alternative, yet its therapeutic ...
Chenhao Yang, Yongxin Xu, Xiaofan Feng, Bowen Wang, Yichao Du, Kexin Wang, Jiaojiao Lü, Lingyan Huang, Zhenyu Qian, Zhen Wang, Nan Chen, Junhong Zhou, Chencheng Zhang, Yu Liu   +13 more
wiley   +1 more source

A computational model of inhibitory control in frontal cortex and basal ganglia [PDF]

arXiv, 2011
Planning and executing volitional actions in the face of conflicting habitual responses is a critical aspect of human behavior. At the core of the interplay between these two control systems lies an override mechanism that can suppress the habitual action selection process and allow executive control to take over.
arxiv  

Rhythmic Eyelid Closure Responsive to STN‐DBS: Blepharoclonus, Blepharospasm, Eyelid Opening Apraxia, or Eyelid Tremor?

Movement Disorders Clinical Practice, EarlyView.
Gianfranco Gaudiano, Alexandra Boogers, Talyta Grippe, Roberto Cilia, Roberto Eleopra, Robert Chen, Alfonso Fasano   +6 more
wiley   +1 more source

Noninvasive Temporal Interference Stimulation of the Subthalamic Nucleus in Parkinson's Disease Reduces Beta Activity

Movement Disorders, EarlyView.
Abstract Background Temporal interference stimulation (TIS) is a novel noninvasive electrical stimulation technique to focally modulate deep brain regions; a minimum of two high‐frequency signals (f1 and f2 > 1 kHz) interfere to create an envelope‐modulated signal at a deep brain target with the frequency of modulation equal to the difference frequency:
Martin Lamoš, Martina Bočková, Florian Missey, Claudia Lubrano, Mariane de Araújo e Silva, Jan Trajlínek, Ondřej Studnička, Pavel Daniel, Romain Carron, Viktor Jirsa, Jan Chrastina, Radim Jančálek, Eric Daniel Glowacki, Antonino Cassara, Esra Neufeld, Irena Rektorová, Adam Williamson   +16 more
wiley   +1 more source

Reply: “Enhancing Parkinson's Disease Research: Recommendations for Addressing Genetic and Environmental Influences in Family History Studies”

Movement Disorders Clinical Practice, EarlyView.
Federica Arienti, Edoardo Monfrini, Alessio Di Fonzo   +2 more
wiley   +1 more source

Comparative Study of Focused Ultrasound Unilateral Thalamotomy and Subthalamotomy for Medication‐Refractory Parkinson's Disease Tremor

Movement Disorders, EarlyView.
Abstract Background Unilateral focused ultrasound ventral intermediate thalamotomy (Vim‐FUS) is effective in treating Parkinson's disease (PD) tremor. Ultrasound ablation of the subthalamic nucleus (STN‐FUS) has demonstrated efficacy in improving all cardinal motor features of PD, including tremor.
Steffen Paschen, Elena Natera‐Villalba, José A. Pineda‐Pardo, Marta del Álamo, Rafael Rodríguez‐Rojas, Johannes Hensler, Günther Deuschl, Jose A. Obeso, Ann‐Kristin Helmers, Raúl Martínez‐Fernández   +9 more
wiley   +1 more source