Brain Imaging Phenotypes Associated with Polygenic Risk for Essential Tremor
Movement Disorders, EarlyView.Abstract Essential tremor (ET) is a common movement disorder with a strong genetic basis. Magnetic resonance imaging (MRI), particularly diffusion‐weighted MRI (dMRI) and T1 MRI, have been used to identify brain abnormalities of ET patients. However, the mechanisms by which genetic risk affects the brain to render individuals vulnerable to ET remain ...
Miranda Medeiros +14 more
wiley +1 more source
Reduced cortical innervation of the subthalamic nucleus in MPTP-treated parkinsonian monkeys.
Brain : a journal of neurology, 2015 The striatum and the subthalamic nucleus are the main entry points for cortical information to the basal ganglia. Parkinson's disease affects not only the function, but also the morphological integrity of some of these inputs and their synaptic targets ...
A. Mathai +5 more
semanticscholar +1 more source
Compressive Cervical Myelopathy Causing Impaired Gait after Deep Brain Stimulation Is Not Rare
Movement Disorders Clinical Practice, EarlyView.
Caroline Weill +6 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Subthalamic beta oscillations are a biomarker for bradykinesia and rigidity in Parkinson's disease (PD), incorporated as a feedback signal in adaptive deep brain stimulation with potential for guiding electrode contact selection.
Jennifer K. Behnke +13 more
wiley +1 more source
Relationship of Activity in the Subthalamic Nucleus–Globus Pallidus Network to Cortical Electroencephalogram [PDF]
, 2000 Peter J. Magill +2 more
openalex +1 more source
Motor Cortex Disinhibition Correlates with Olfactory Dysfunction in Parkinson's Disease
Movement Disorders, EarlyView.Abstract Background Motor cortex disinhibition, as measured by impaired short‐interval intracortical inhibition (SICI) using transcranial magnetic stimulation (TMS), is a well‐established feature of Parkinson's disease (PD). However, its substantial variability among patients remains unexplained, prompting questions about its origin, clinical relevance,
Claudia Ammann +12 more
wiley +1 more source
Stroke Mimicking Thalamotomy in Primary Familial Brain Calcification
Movement Disorders Clinical Practice, EarlyView.
Jaakko Kungshamn +4 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Spinocerebellar ataxia 27A (SCA27A) is a rare neurodegenerative disorder characterized by childhood‐onset tremor and progressive cerebellar dysfunction. SCA27A is usually caused by loss‐of‐function FGF14 variants. Objectives We report the identification of a novel FGF14 variant in a five‐generation family with autosomal dominant ...
Ignacio J. Keller Sarmiento +6 more
wiley +1 more source
High-frequency Synchronization of Neuronal Activity in the Subthalamic Nucleus of Parkinsonian Patients with Limb Tremor [PDF]
, 2000 Ron Levy +3 more
openalex +1 more source
Antero‐Lateral Subthalamic Nucleus Theta Stimulation Improves Verbal Fluency in Parkinson's Disease
Movement Disorders, EarlyView.Abstract Objective Low‐frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been associated with positive effects on verbal fluency (VF) in patients with Parkinson's disease. This prospective study investigates stimulation direction‐dependent and site‐specific effects of theta frequency DBS on VF. Methods In a double‐blind, cross‐
Hannah Schoenwald +12 more
wiley +1 more source