Differential Effects of Levodopa and Stimulation on Post-Surgery Freezing of Gait in Subthalamic Nucleus Deep Brain Stimulation Parkinson's Disease Patients: A Clinical and Kinematic Analysis. [PDF]
Mov Disord Clin PractAbstract Background The long‐term efficacy of high‐frequency subthalamic nucleus deep brain stimulation (STN‐DBS) on freezing of gait (FOG) remains unclear. We aimed to study the mechanism and optimal therapeutic approach to long‐term post‐surgery FOG.
Barbosa R +13 more
europepmc +2 more sources
Vessel segmentation for χ$$ \chi $$‐separation in quantitative susceptibility mapping
Magnetic Resonance in Medicine, Volume 95, Issue 1, Page 382-399, January 2026.Abstract Purpose χ$$ \chi $$‐separation is an advanced quantitative susceptibility mapping (QSM) method that is designed to generate paramagnetic (χpara$$ {\chi}_{para} $$) and diamagnetic (|χdia|$$ \mid {\chi}_{dia}\mid $$) susceptibility maps, reflecting the distribution of iron and myelin in the brain.
Taechang Kim +7 more
wiley +1 more source
Association of emotional and behavioral problems with the development of the substantia nigra, subthalamic nucleus, and red nucleus volumes and asymmetries from childhood to adolescence: A longitudinal cohort study [PDF]
Yanpei Wang +10 more
openalex +1 more source
Unsupervised Clustering Reveals Spatially Varying Single Neuronal Firing Patterns in the Subthalamic Nucleus of Patients with Parkinson’s Disease [PDF]
, 2019 Heet Kaku +6 more
openalex +1 more source
Journal of Human Nutrition and Dietetics, Volume 38, Issue 6, December 2025.Whilst a range of nutrition support interventions for those undergoing osteosarcoma treatment has been studied and interest is growing, the evidence is fragmented, methodologically weak and indicates wide variation in clinical practice. We identify priority research needed to establish evidence‐based clinical practice guidance.
Laura Sealy +5 more
wiley +1 more source
Neuropathology, Volume 45, Issue 6, December 2025.ABSTRACT Herein, we report two autopsy cases of familial ALS with a p. L127S (L126S) SOD1 variant. Case 1 involved a 62‐year‐old woman who presented with lower‐extremity muscle weakness with lower motor neuron signs. The patient developed bulbar palsy and died of respiratory failure 9 years after onset.
Kimiko Inoue +6 more
wiley +1 more source
Central Dysmyelination in SSADH‐Deficient Humans and Mice
Annals of Clinical and Translational Neurology, Volume 12, Issue 11, Page 2193-2205, November 2025.ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer +11 more
wiley +1 more source
Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders
Advanced Functional Materials, Volume 35, Issue 46, November 12, 2025.This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao +5 more
wiley +1 more source