Results 31 to 40 of about 490,973 (323)
Potential mechanisms for imperfect synchronization in parkinsonian basal ganglia [PDF]
, 2012 Neural activity in the brain of parkinsonian patients is characterized by the intermittently synchronized oscillatory dynamics. This imperfect synchronization, observed in the beta frequency band, is believed to be related to the hypokinetic motor ...
Park, Choongseok, Rubchinsky, Leonid
core +9 more sources
Anatomy and Connectivity of the Subthalamic Nucleus in Humans and Non-human Primates
Frontiers in Neuroanatomy, 2020 The Subthalamic Nucleus (STh) is an oval-shaped diencephalic structure located ventrally to the thalamus, playing a fundamental role in the circuitry of the basal ganglia.
A. Emmi +4 more
semanticscholar +1 more source
Subthalamic Nucleus Deep Brain Stimulation Modulates 2 Distinct Neurocircuits
Annals of Neurology, 2020 Current understanding of the neuromodulatory effects of deep brain stimulation (DBS) on large‐scale brain networks remains elusive, largely due to the lack of techniques that can reveal DBS‐induced activity at the whole‐brain level.
Lunhao Shen +13 more
semanticscholar +1 more source
Imaging of the human subthalamic nucleus
, 2021 The human subthalamic nucleus (STN) is a small lens shaped iron rich nucleus, which has gained substantial interest as a target for deep brain stimulation surgery for a variety of movement disorders. The internal anatomy of the human STN has not been fully elucidated, and an intensive debate, discussing the level of overlap between putative limbic ...
Alkemade, A., Forstmann, B.U.
openaire +4 more sources
Brain tissue properties differentiate between motor and limbic basal ganglia circuits [PDF]
, 2014 Despite advances in understanding basic organizational principles of the human basal ganglia, accurate in vivo assessment of their anatomical properties is essential to improve early diagnosis in disorders with corticosubcortical pathology and optimize ...
Accolla, EA +10 more
core +6 more sources
A role for the subthalamic nucleus in aversive learning
Cell Reports, 2023 The subthalamic nucleus (STN) is critical for behavioral control; its dysregulation consequently correlated with neurological and neuropsychiatric disorders, including Parkinson's disease. Deep brain stimulation (DBS) targeting the STN successfully alleviates parkinsonian motor symptoms. However, low mood and depression are affective side effects.
Serra, Gian Pietro +9 more
openaire +4 more sources
Development of a novel gripping test for the evaluation of the finger fine motor ability in MPTP-treated monkeys [PDF]
Journal of Integrative Neuroscience, 2020 Assessing the finger fine motor ability is extremely important. However, conventional behavioral tests in monkeys are complicated and costly. We attempted to develop a new task to assess the precise finger grip in Parkinson's disease monkeys based on the
Susumu Kobayashi, Tetsuya Asakawa, Takao Nozaki, Kenji Sugiyama, Tetsuro Sameshima, Kazuhiko Kurozumi
doaj +1 more source
Scientific Reports, 2017 We aimed to explore the effects of bilateral subthalamic nucleus stimulation and levodopa on cardiovascular autonomic function in Parkinson’s disease.
Kai Li +6 more
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The subcortical cocktail problem; mixed signals from the subthalamic nucleus and substantia nigra.
PLoS ONE, 2015 The subthalamic nucleus and the directly adjacent substantia nigra are small and important structures in the basal ganglia. Functional magnetic resonance imaging studies have shown that the subthalamic nucleus and substantia nigra are selectively ...
Gilles de Hollander +2 more
doaj +1 more source
Translational Psychiatry, 2022 Patients with psychiatric symptoms, such as depression, anxiety, and visual hallucinations, may be at increased risk for adverse effects following deep brain stimulation of the subthalamic nucleus for Parkinson’s disease, but there have been relatively ...
Ian H. Kratter +7 more
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