Results 31 to 40 of about 40,678 (327)

Topography and distribution of adenosine A2A and dopamine D2 receptors in the human Subthalamic Nucleus

Frontiers in Neuroscience, 2022
The human Subthalamic Nucleus (STh) is a diencephalic lens-shaped structure located ventrally to the thalamus and functionally implicated in the basal ganglia circuits.
Aron Emmi, Aron Emmi, Aron Emmi, Angelo Antonini, Angelo Antonini, Michele Sandre, Michele Sandre, Andrea Baldo, Martina Contran, Veronica Macchi, Veronica Macchi, Diego Guidolin, Andrea Porzionato, Andrea Porzionato, Raffaele De Caro, Raffaele De Caro   +15 more
doaj   +1 more source

Neurotransmitter and receptor systems in the subthalamic nucleus

Brain Structure and Function, 2023
AbstractThe Subthalamic Nucleus (STh) is a lens-shaped subcortical structure located ventrally to the thalamus, that despite being embryologically derived from the diencephalon, is functionally implicated in the basal ganglia circuits. Because of this strict structural and functional relationship with the circuits of the basal ganglia, the STh is a ...
Emmi, Aron, Campagnolo, Marta, Stocco, Elena, Carecchio, Miryam, Macchi, Veronica, Antonini, Angelo, De Caro, Raffaele, Porzionato, Andrea   +7 more
openaire   +4 more sources

The subthalamic nucleus becomes a generator of bursts in the dopamine-depleted state. Its high frequency stimulation dramatically weakens transmission to the globus pallidus

Frontiers in Systems Neuroscience, 2011
Excessive burst firing in the dopamine-depleted basal ganglia correlates with severe motor symptoms of Parkinson’s disease that are attenuated by high frequency electrical stimulation of the subthalamic nucleus.
Rachida eAmmari, Rachida eAmmari, Bernard eBioulac, Liliana eGarcia, Constance eHammond   +4 more
doaj   +1 more source

Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease [PDF]

, 2003
Background: Although the short-term benefits of bilateral stimulation of the subthalamic nucleus in patients with advanced Parkinson's disease have been well documented, the long-term outcomes of the procedure are unknown. Methods: We conducted a five-
Krack, P., Batir, A., Van Blercom, N., Chabardes, S., Fraix, V., Ardouin, C., Koudsie, A., Limousin, P.D., Benazzouz, A., LeBas, J.F., Benabid, A.-L., Pollak, P.   +11 more
core   +4 more sources

Decisional impulsivity and the associative-limbic subthalamic nucleus in obsessive-compulsive disorder: stimulation and connectivity. [PDF]

, 2016
Why do we make hasty decisions for short-term gain? Rapid decision-making with limited accumulation of evidence and delay discounting are forms of decisional impulsivity.
Bougerol, Thierry, Chabardes, Stephan, David, Olivier, Droux, Fabien, Krack, Paul, Morris, Laurel, Polosan, Mircea, Voon, Valerie   +7 more
core   +2 more sources

A role for the subthalamic nucleus in aversive learning

Cell Reports, 2023
The subthalamic nucleus (STN) is critical for behavioral control; its dysregulation consequently correlated with neurological and neuropsychiatric disorders, including Parkinson's disease. Deep brain stimulation (DBS) targeting the STN successfully alleviates parkinsonian motor symptoms. However, low mood and depression are affective side effects.
Serra, Gian Pietro, Guillaumin, Adriane, Vlcek, Bianca, Delgado-Zabalza, Lorena, Ricci, Alessia, Rubino, Eleonora, Dumas, Sylvie, Baufreton, Jerome, Georges, Francois, Wallén-Mackenzie, Åsa   +9 more
openaire   +4 more sources

Optogenetics and deep brain stimulation neurotechnologies [PDF]

, 2015
Brain neural network is composed of densely packed, intricately wired neurons whose activity patterns ultimately give rise to every behavior, thought, or emotion that we experience. Over the past decade, a novel neurotechnique, optogenetics that combines
A Berndt, A Berndt, A Priori, AA Kuhn, AA Kuhn, AS Chuong, B Sauer, B Wingeier, BY Chow, BY Chow, C Bamann, D Luo, D Oesterhelt, D Oesterhelt, D Williams, ES Boyden, EY Uc, F Zhang, F Zhang, G Foffani, G Miesenbock, G Nagel, J Cavanaugh, J Mobley, J Volkmann, J Wells, J Wietek, JG Bernstein, JG Bernstein, JG Bernstein, JL Spudich, JL Spudich, JO Dostrovsky, JZ Tsien, L Bekar, L Madisen, LA Gunaydin, M Weinberger, M Weinberger, MC Rodriguez-Oroz, MJ Lehmkuhle, ML Welter, MM Doroudchi, O Yizhar, P Brown, P Silberstein, R Levy, R Levy, R Levy, R Waehler, S Zhao, TW Chen, VC Anderson, X Han, X Han, X Han, X Han, X Han, X Liu   +58 more
core   +2 more sources

The next step for imaging the subthalamic nucleus [PDF]

Brain, 2016
Sir, We read with interest the recently published study by Accolla and colleagues (2016) on brain networks modulated by subthalamic nucleus deep brain stimulation (DBS; Accolla et al. , 2016). In their study, the authors combined neurophysiological recordings with MRI to obtain much needed, more detailed information on the functional organization of ...
Birte U. Forstmann, Birte U. Forstmann, Anneke Alkemade, Anneke Alkemade, Max C. Keuken, Max C. Keuken   +5 more
openaire   +5 more sources

Informed consent decision-making in deep brain stimulation [PDF]

, 2018
Deep brain stimulation (DBS) has proved useful for several movement disorders (Parkinson’s disease, essential tremor, dystonia), in which first and/or second line pharmacological treatments were inefficacious.
Appelbaum, Bell, Berg, Gilbert, Grisso, Jahanshahi, Mehdorn   +6 more
core   +2 more sources

Subthalamic nucleus stimulation and levodopa modulate cardiovascular autonomic function in Parkinson’s disease

Scientific Reports, 2017
We aimed to explore the effects of bilateral subthalamic nucleus stimulation and levodopa on cardiovascular autonomic function in Parkinson’s disease.
Kai Li, Rocco Haase, Heinz Rüdiger, Manja Reimann, Heinz Reichmann, Martin Wolz, Tjalf Ziemssen   +6 more
doaj   +1 more source