Results 21 to 30 of about 54,156 (279)

Safety evaluation of the food enzyme subtilisin from the non‐genetically modified Bacillus paralicheniformis strain DP‐Dzx96

open access: yesEFSA Journal, 2023
The food enzyme subtilisin (serine endopeptidase, EC 3.4.21.62) is produced with the non‐genetically modified Bacillus paralicheniformis strain DP‐Dzx96 by Genencor International B.V.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP)   +22 more
doaj   +1 more source

Subtilisin-Involved Morphology Engineering for Improved Antibiotic Production in Actinomycetes

open access: yesBiomolecules, 2020
In the submerged cultivation of filamentous microbes, including actinomycetes, complex morphology is one of the critical process features for the production of secondary metabolites.
Yuanting Wu   +3 more
doaj   +1 more source

Directed evolution converts subtilisin E into a functional equivalent of thermitase [PDF]

open access: yes, 1999
We used directed evolution to convert Bacillus subtilis subtilisin E into an enzyme functionally equivalent to its thermophilic homolog thermitase from Thermoactinomyces vulgaris.
Arnold, Frances H., Zhao, Huimin
core   +2 more sources

Proteases Shape the Chlamydomonas Secretome: Comparison to Classical Neuropeptide Processing Machinery

open access: yesProteomes, 2018
The recent identification of catalytically active peptidylglycine α-amidating monooxygenase (PAM) in Chlamydomonas reinhardtii, a unicellular green alga, suggested the presence of a PAM-like gene and peptidergic signaling in the last eukaryotic ...
Raj Luxmi   +6 more
doaj   +1 more source

Phylogenetic survey of the subtilase family and a data-mining-based search for new subtilisins from Bacillaceae

open access: yesFrontiers in Microbiology, 2022
The subtilase family (S8), a member of the clan SB of serine proteases are ubiquitous in all kingdoms of life and fulfil different physiological functions.
Fabian Falkenberg   +3 more
doaj   +1 more source

Pharmaceutically modified subtilisins withstand acidic conditions and effectively degrade gluten in vivo [PDF]

open access: yes, 2019
Detoxification of gluten immunogenic epitopes is a promising strategy for the treatment of celiac disease. Our previous studies have shown that these epitopes can be degraded in vitro by subtilisin enzymes derived from Rothia mucilaginosa, a natural ...
Darwish, Ghassan   +4 more
core   +1 more source

Non-canonical proteolytic activation of human prothrombin by subtilisin from Bacillus subtilis may shift the procoagulant\ue2\u80\u93anticoagulant equilibrium toward thrombosis [PDF]

open access: yes, 2017
Blood coagulation is a finely regulated physiological process culminating with the factor Xa (FXa)-mediated conversion of the prothrombin (ProT) zymogen to active -thrombin (T).
Acquasaliente, Laura   +5 more
core   +1 more source

Identification of Key Residues Essential for the Activation of Plant Immunity by Subtilisin From Bacillus velezensis LJ02

open access: yesFrontiers in Microbiology, 2022
Subtilisin, a serine protease, can trigger defense responses in a wide variety of plants, both locally and systemically, to protect against pathogens. However, key residues of subtilisin to improve resistance to plant diseases remain unknown.
Jianan Hu   +4 more
doaj   +1 more source

A new subfamily of fungal subtilases: structural and functional analysis of a Pleurotus ostreatus member [PDF]

open access: yes, 2005
Pleurotus ostreatus produces several extracellular proteases which are believed to be involved in the regulation of the ligninolytic activities of this fungus. Recently, purification and characterization of the most abundant P.
FARACO, VINCENZA   +5 more
core   +2 more sources

Dependence and Guidance Receptors—DCC and Neogenin—In Partial EMT and the Actions of Serine Proteases

open access: yesFrontiers in Oncology, 2020
The Epithelial-Mesenchymal Transition (EMT) is an important concept in understanding the processes of oncogenesis, especially with respect to the relationship between cell proliferation and metastatic properties such as spontaneous cell motility ...
Trevor W. Stone
doaj   +1 more source

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