Results 31 to 40 of about 25,546 (199)
EFSA Journal, 2020 Avizyme® 1505 is based on three enzyme activities produced by three genetically modified microorganisms: xylanase, subtilisin and amylase produced by Trichoderma reesei, Bacillus subtilis and Bacillus amyloliquefaciens, respectively. It is authorised for
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +29 more
doaj +1 more source
Heliyon, 2022 The efficacy and safety of a novel Subtilisin protease from a Bacillus sp. produced in Bacillus licheniformis was investigated in broiler chickens, and a range of toxicological tests, respectively. The B.
Denisa Cupi +6 more
doaj +1 more source
HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox". [PDF]
, 2016 BackgroundProprotein convertase subtilisin kexin 9 (PCSK9) inhibitors reduce low-density lipoprotein cholesterol (LDL-C) and improve outcomes in the general population.
Deeks, Steven +10 more
core +1 more source
Crystal structure of subtilisin DY, a random mutant of subtilisin Carlsberg [PDF]
European Journal of Biochemistry, 1998 The crystal structure of subtilisin DY inhibited by N‐benzyloxycarbonyl‐Ala‐Pro‐Phe‐chloromethyl ketone has been solved by molecular replacement with subtilisin Carlsberg as the starting model. The model has been refined to a crystallographic R factor (= Σ∣∣Fo∣−∣Fc∣∣ / Σ∣Fo∣) of 15.1 % using X‐ray diffraction data to 0.175 nm resolution.
S, Eschenburg +6 more
openaire +2 more sources
Frontiers in Oncology, 2020 The Epithelial-Mesenchymal Transition (EMT) is an important concept in understanding the processes of oncogenesis, especially with respect to the relationship between cell proliferation and metastatic properties such as spontaneous cell motility ...
Trevor W. Stone
doaj +1 more source
Obesity and cancer: existing and new hypotheses for a causal connection [PDF]
, 2018 Existing explanations of obesity-associated cancer emphasise direct mutagenic effects of dietary components or hormonal imbalance. Some of these hypotheses are reviewed briefly, but recent evidence suggests a major role for chronic inflammation in cancer
Darlington, L. Gail +2 more
core +2 more sources
Subtilisin-Involved Morphology Engineering for Improved Antibiotic Production in Actinomycetes
Biomolecules, 2020 In the submerged cultivation of filamentous microbes, including actinomycetes, complex morphology is one of the critical process features for the production of secondary metabolites.
Yuanting Wu +3 more
doaj +1 more source
Unpacking and understanding the impact of proprotein convertase subtilisin/kexin type 9 inhibitors on apolipoprotein B metabolism [PDF]
, 2017 No abstract ...
Packard, Chris J.
core +1 more source
Angewandte Chemie, EarlyView.This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis +2 more
wiley +2 more sources
Development of Versatile Vectors for Heterologous Expression in Bacillus
Microorganisms, 2018 The discovery of new enzymes for industrial application relies on a robust discovery pipeline. Such a pipeline should facilitate efficient molecular cloning, recombinant expression and functional screening procedures.
Øivind Larsen +1 more
doaj +1 more source