The subunit vaccine of Lumpy skin disease virus elicits significant humoral and cell-mediated immune responses in mice. [PDF]
Gu X +7 more
europepmc +1 more source
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng +8 more
wiley +1 more source
Impaired cellular immune responses to herpes zoster subunit vaccine in patients with rheumatoid arthritis receiving Janus kinase inhibitors. [PDF]
Källmark H +7 more
europepmc +1 more source
Simple incubation with DP7‐C enables the generation of extracellular vesicles (DP‐EVs) with enhanced both tumor and lymph nodes targeting properties. DP‐EVs/siPD‐L1 can effectively inhibit tumor growth and greatly prolong the survival of tumor bearing mice through immune response activation and tumor microenvironment reprogramming.
Yusi Wang +8 more
wiley +1 more source
The TamA protein as a subunit vaccine improves immune protection against highly virulent <i>Klebsiella pneumoniae</i> infection in mice. [PDF]
Liu L +7 more
europepmc +1 more source
MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential
The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman +7 more
wiley +1 more source
<i>In silico</i> design of a multiepitope subunit vaccine targeting <i>Salmonella enterica</i> serovar Infantis: an immunoinformatics and reverse vaccinology approach. [PDF]
Chundru D, Ghanem M.
europepmc +1 more source
A lipopeptide is designed that contains an epitope from simian virus T‐antigen (SV40T, PKKKRKV) conjugated to an N‐terminal palmitoyl (C16‐) moiety, which acts as a cell‐penetrating lipopeptide, with additional aggregation propensity conferred by the lipid chain. The lipopeptide enables DNA delivery into the cytoplasm and nucleus.
Lucas R. de Mello +6 more
wiley +1 more source
A Novel Chimeric Fiber-C4/D11 Subunit Vaccine Induces Cross-Neutralizing Antibodies and Provides Better Protection Against Fowl Adenovirus (FAdV) Type 4 and Type 11 Than the Fiber-D11/C4 Subunit Vaccine. [PDF]
Wang X +5 more
europepmc +1 more source
Structural Basis of MERS‐CoV Receptor Interactions and Antibody Neutralisations
ABSTRACT Increasing outbreaks of coronaviruses underscore the importance of antivirals and vaccines that can combat a wide range of coronaviruses. Neutralising antibodies (nAbs), along with vaccines and small‐molecule drugs, are among the most promising treatments and prevention options against coronaviruses.
Edem Gavor +5 more
wiley +1 more source

