Results 41 to 50 of about 1,122,864 (370)
Raising Expectations For Subunit Vaccine [PDF]
The Journal of Infectious Diseases, 2014 Multidose regimens are recommended for all prophylactic subunit vaccines. Recent findings from clinical trials of an human papillomavirus virus-like particle vaccine suggest that it may be possible to develop effective single-dose subunit vaccines.
John T, Schiller, Douglas R, Lowy
openaire +2 more sources
Future Path Toward TB Vaccine Development: Boosting BCG or Re-educating by a New Subunit Vaccine
Frontiers in Immunology, 2018 Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb), kills 5,000 people per day globally. Rapid development and spread of various multi drug-resistant strains of Mtb emphasize that an effective vaccine is still the most ...
Nancy Gupta +5 more
doaj +1 more source
S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates
Nature Communications, 2020 SARS-CoV-2 is the underlying cause for the COVID-19 pandemic. Like most enveloped RNA viruses, SARS-CoV-2 uses a homotrimeric surface antigen to gain entry into host cells.
Joshua G. Liang +24 more
semanticscholar +1 more source
npj Vaccines, 2022 Adjuvants enhance the magnitude and the durability of the immune response to vaccines. However, there is a paucity of comparative studies on the nature of the immune responses stimulated by leading adjuvant candidates.
Lilit Grigoryan +29 more
semanticscholar +1 more source
Viral Subunits for Rabies Vaccination [PDF]
Nature, 1969 RECENT work with adenovirus1, Sindbis virus2 and the viruses causing influenza3, measles4, vesicular stomatitis5 and German measles6 has shown that subunits of the viruses can stimulate the production of neutralizing antibodies, and in some cases can be used as vaccines.
J, Crick, F, Brown
openaire +2 more sources
Avoiding rash decisions about zoster vaccination: insights from cost-effectiveness evidence
BMC Medicine, 2018 de Boer and colleagues present a cost-effectiveness analysis based in the Netherlands of two vaccines available for the prevention of herpes zoster. Zostavax® was the first vaccine available for the prevention of herpes zoster in older adults.
Chester B. Good +2 more
doaj +1 more source
Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium [PDF]
, 2019 Funding text The authors are grateful for the vital contributions of the participating study volunteers, clinicians, nurses, and laboratory technicians at the Surrey study site.
Bodinham, C. +16 more
core +1 more source
Carbohydrate Immune Adjuvants in Subunit Vaccines [PDF]
Pharmaceutics, 2020 Modern subunit vaccines are composed of antigens and a delivery system and/or adjuvant (immune stimulator) that triggers the desired immune responses. Adjuvants mimic pathogen-associated molecular patterns (PAMPs) that are typically associated with infections.
Sahra Bashiri +3 more
openaire +4 more sources
Duality of β-glucan microparticles: antigen carrier and immunostimulants [PDF]
, 2016 Designing efficient recombinant mucosal vaccines against enteric diseases is still a major challenge. Mucosal delivery of recombinant vaccines requires encapsulation in potent immunostimulatory particles to induce an efficient immune response. This paper
Baert, Kim +4 more
core +2 more sources
Vaccines, 2020 Respiratory syncytial virus (RSV) is primarily associated with respiratory disorders globally. Despite the availability of information, there is still no competitive vaccine available for RSV.
Muhammad Tahir ul Qamar +8 more
semanticscholar +1 more source