Results 21 to 30 of about 1,747,151 (350)

Humoral immunity and transcriptome differences of COVID-19 inactivated vacciane and protein subunit vaccine as third booster dose in human

Frontiers in Immunology, 2022
Under the background of the severe human health and world economic burden caused by COVID-19, the attenuation of vaccine protection efficacy, and the prevalence and immune escape of emerging variants of concern (VOCs), the third dose of booster ...
Yuwei Zhang, Mingxiao Yao, Xingyu Guo, Shanshan Han, Shu Zhang, Jinzhong Zhang, Xiangkun Jiang, Jianxing Wang, Ming Fang, Shuang Wang, Bo Pang, Xiaolin Liu, Zengqiang Kou, Xiaolin Jiang, Xiaolin Jiang   +14 more
doaj   +1 more source

An overview of the vaccine platforms to combat COVID-19 with a focus on the subunit vaccines

Progress in Biophysics and Molecular Biology, 2023
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging virus that has caused the recent coronavirus disease (COVID-19) global pandemic. The current approved COVID-19 vaccines have shown considerable efficiency against hospitalization
Fatemeh Bayani, Negin Safaei Hashkavaei, S. Arjmand, Shokouh Rezaei, V. Uskoković, M. Alijanianzadeh, V. Uversky, Seyed Omid Ranaei Siadat, S. Mozaffari-Jovin, Yahya Sefidbakht   +9 more
semanticscholar   +1 more source

Immunogenicity and protective efficacy of OmpA subunit vaccine against Aeromonas hydrophila infection in Megalobrama amblycephala: An effective alternative to the inactivated vaccine

Frontiers in Immunology, 2023
Aeromonas hydrophila is a kind of zoonotic pathogen, which can cause bacterial septicemia in fish and bring huge economic losses to global aquaculture. Outer membrane proteins (Omps) are conserved antigens of Aeromonas hydrophila, which can be developed ...
Minying Zhang, Ting Zhang, Yang He, Hujun Cui, Hujun Cui, Hong Li, Zehua Xu, Xu Wang, Yunlong Liu, Hongping Li, Xiaoheng Zhao, Xiaoheng Zhao, Hanliang Cheng, Hanliang Cheng, Jianhe Xu, Jianhe Xu, Xiangning Chen, Xiangning Chen, Zhujin Ding, Zhujin Ding   +19 more
doaj   +1 more source

Immunogenicity of prime-boost protein subunit vaccine strategies against SARS-CoV-2 in mice and macaques

Nature Communications, 2021
SARS-CoV-2 vaccines are advancing into human clinical trials, with emphasis on eliciting high titres of neutralising antibodies against the viral spike (S).
Hyon-Xhi Tan, J. Juno, W. Lee, Isaac M. Barber-Axthelm, Hannah G. Kelly, Kathleen M. Wragg, R. Esterbauer, T. Amarasena, F. Mordant, K. Subbarao, S. Kent, A. Wheatley   +11 more
semanticscholar   +1 more source

Subunit vaccines for Acinetobacter baumannii

Frontiers in Immunology, 2023
Acinetobacter baumannii is a gram-negative bacterium and a crucial opportunistic pathogen in hospitals. A. baumannii infection has become a challenging problem in clinical practice due to the increasing number of multidrug-resistant strains and their prevalence worldwide. Vaccines are effective tools to prevent and control A. baumannii infection.
Ning Yang, Xiao Jin, Chenghua Zhu, Fenglin Gao, Zheqi Weng, Xingran Du, Ganzhu Feng   +6 more
openaire   +3 more sources

Acute retinal necrosis following recombinant subunit varicella-zoster virus vaccine

American Journal of Ophthalmology Case Reports, 2020
Purpose: Previously, secondary prevention of herpes zoster required live-attenuated vaccination, which is contraindicated in immunocompromised populations.
Rebecca I. Chen, Jordan D. Deaner, Sunil K. Srivastava, Careen Y. Lowder   +3 more
doaj   +1 more source

Evaluation of immunogenicity of gene-deleted and subunit vaccines constructed against the emerging pseudorabies virus variants

Virology Journal, 2023
Background Pseudorabies (PR) (also called Aujeszky’s disease, AD) is a serious infectious disease affecting pigs and other animals worldwide. The emergence of variant strains of pseudorabies virus (PRV) since 2011 has led to PR outbreaks in China and a ...
Hong-liang Zhang, Rui-hua Zhang, Gang Liu, Gui-mei Li, Feng-xue Wang, Yong-jun Wen, Hu Shan   +6 more
doaj   +1 more source

SARS-CoV-2 subunit vaccine adjuvants and their signaling pathways

Expert Review of Vaccines, 2021
Introduction Vaccines are the agreed upon weapon against the COVID-19 pandemic. This review discusses about COVID-19 subunit vaccines adjuvants and their signaling pathways, which could provide a glimpse into the selection of appropriate adjuvants for ...
D. Mekonnen, H. M. Mengist, T. Jin
semanticscholar   +1 more source

RABIES SUBUNIT VACCINES

Journal of General Virology, 1983
Conclusions The secondary and tertiary structures of the rabies virus spike G protein are important for its ability to induce VN antibodies and confer immunity to the host. For a subunit peptide vaccine to be as effective as the native spike G protein, it would appear that the amino acid sequence comprising the antigenic determinant for VN antibody ...
W H, Wunner, B, Dietzschold, P J, Curtis, T J, Wiktor   +3 more
openaire   +2 more sources

Subunit Vaccine Against Sars-Cov-2 Using CTL and HTL Epitopes [PDF]

, 2021
Severe Acute Respiratory Syndrome coronavirus 2 which is widely known as Sars-Cov-2 is a deadly virus that is the main cause of Coronavirus Disease (COVID-19). This plague affects the human immune system badly and adversely affects the human body. This
Yaser Daanial, Khan, Laila, zahra
core   +1 more source