Results 21 to 30 of about 83,566 (244)

Effect of adjuvants on responses to skin immunization by microneedles coated with influenza subunit vaccine.

PLoS ONE, 2012
Recent studies have demonstrated the effectiveness of vaccine delivery to the skin by vaccine-coated microneedles; however there is little information on the effects of adjuvants using this approach for vaccination.
William C Weldon, Vladimir G Zarnitsyn, E Stein Esser, Misha T Taherbhai, Dimitrios G Koutsonanos, Elena V Vassilieva, Ioanna Skountzou, Mark R Prausnitz, Richard W Compans   +8 more
doaj   +1 more source

Heat-inactivated modified vaccinia virus Ankara boosts Th1 cellular and humoral immunity as a vaccine adjuvant

npj Vaccines, 2022
Protein or peptide-based subunit vaccines have generated excitement and renewed interest in combating human cancer or COVID-19 outbreak. One major concern for subunit vaccine application is the weak immune responses induced by protein or peptides ...
Ning Yang, Aitor Garcia, Cindy Meyer, Thomas Tuschl, Taha Merghoub, Jedd D. Wolchok, Liang Deng   +6 more
doaj   +1 more source

CHO-produced RBD-Fc subunit vaccines with alternative adjuvants generate immune responses against SARS-CoV-2.

PLoS ONE, 2023
Subunit vaccines feature critical advantages over other vaccine platforms such as stability, price, and minimal adverse effects. To maximize immunological protection of subunit vaccines, adjuvants are considered as main components that are formulated ...
Sedthawut Laotee, Methawee Duangkaew, Araya Jivapetthai, Kittipan Tharakhet, Papatsara Kaewpang, Eakachai Prompetchara, Supaporn Phumiamorn, Sompong Sapsutthipas, Sakalin Trisiriwanich, Thitiporn Somsaard, Sittiruk Roytrakul, Parichat Duangkhae, Boonsri Ongpipattanakul, Patanachai Limpikirati, Natapol Pornputtapong, Wanatchaporn Arunmanee   +15 more
doaj   +1 more source

Future Path Toward TB Vaccine Development: Boosting BCG or Re-educating by a New Subunit Vaccine

Frontiers in Immunology, 2018
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb), kills 5,000 people per day globally. Rapid development and spread of various multi drug-resistant strains of Mtb emphasize that an effective vaccine is still the most ...
Nancy Gupta, Saurabh Garg, Satish Vedi, Dennis Y. Kunimoto, Rakesh Kumar, Babita Agrawal   +5 more
doaj   +1 more source

Avoiding rash decisions about zoster vaccination: insights from cost-effectiveness evidence

BMC Medicine, 2018
de Boer and colleagues present a cost-effectiveness analysis based in the Netherlands of two vaccines available for the prevention of herpes zoster. Zostavax® was the first vaccine available for the prevention of herpes zoster in older adults.
Chester B. Good, Natasha Parekh, Inmaculada Hernandez   +2 more
doaj   +1 more source

A single dose investigational subunit vaccine for human use against Nipah virus and Hendra virus

npj Vaccines, 2021
Nipah and Hendra viruses are highly pathogenic bat-borne paramyxoviruses recently included in the WHO Blueprint priority diseases list. A fully registered horse anti-Hendra virus subunit vaccine has been in use in Australia since 2012.
Thomas W. Geisbert, Kathryn Bobb, Viktoriya Borisevich, Joan B. Geisbert, Krystle N. Agans, Robert W. Cross, Abhishek N. Prasad, Karla A. Fenton, Hao Yu, Timothy R. Fouts, Christopher C. Broder, Antony S. Dimitrov   +11 more
doaj   +1 more source

Herpes zoster and subunit vaccine

Uirusu, 2021
Varicella-zoster virus (VZV) causes varicella (chickenpox) as primary infection, and latently infects neuronal cells in the dorsal root ganglia (DRG). Reactivation of VZV from DRG results in herpes zoster, often decades later. VZV is the only airborne human herpesvirus and the only herpesvirus whose symptoms (both varicella and herpes zoster) can be ...
openaire   +2 more sources

Cytokine Profile in Human Peripheral Blood Mononuclear Leukocytes Exposed to Immunoadjuvant and Adjuvant-Free Vaccines Against Influenza

Frontiers in Immunology, 2020
Background: In the last decade, adjuvant-containing vaccines, exerting different effects on the immune system, including the production of cytokines, which are one of the most important regulatory systems of the body, are introduced into practice ...
Mikhail Petrovich Kostinov, Mikhail Petrovich Kostinov, Nelli Kimovna Akhmatova, Ekaterina Alexandrovna Khromova, Aristitsa Mikhailovna Kostinova   +4 more
doaj   +1 more source

Evaluation of classical swine fever E2 (CSF-E2) subunit vaccine efficacy in the prevention of virus transmission and impact of maternal derived antibody interference in field farm applications

Porcine Health Management, 2021
Background Classical swine fever (CSF) is one of the most devastating pig diseases that affect the swine industry worldwide. Besides stamping out policy for eradication, immunization with vaccines of live attenuated CSF or the CSF-E2 subunit is an ...
Jing-Yuan Chen, Chi-Ming Wu, Zeng-Weng Chen, Chih-Ming Liao, Ming-Chung Deng, Min-Yuan Chia, Chienjin Huang, Maw-Sheng Chien   +7 more
doaj   +1 more source

A bivalent subunit bovine herpesvirus 1 vaccine based on the ectodomains of glycoproteins D and B elicits robust protective immunity against infection in a rabbit model

Veterinary Quarterly
Bovine alphaherpesvirus 1 (BoHV-1) is the causative agent of infectious bovine rhinotracheitis and reproductive disorders causing significant economic losses in the cattle industry.
Wenxiao Liu, Chun Yang, Jijing Tian, Jing Cheng, Linyi Zhou, Munir Iqbal, Arslan Mehboob, Rebecca Daines, Sui Zhang, Mengjiao Chen, Xiaoying Wang, Yongqing Li   +11 more
doaj   +1 more source