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Advances in Oral Subunit Vaccine Design [PDF]
Vaccines, 2020 Many pathogens invade the host at the intestinal surface. To protect against these enteropathogens, the induction of intestinal secretory IgA (SIgA) responses is paramount. While systemic vaccination provides strong systemic immune responses, oral vaccination is the most efficient way to trigger protective SIgA responses.
Hans Van der Weken +2 more
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Frontiers in Immunology, 2022 Under the background of the severe human health and world economic burden caused by COVID-19, the attenuation of vaccine protection efficacy, and the prevalence and immune escape of emerging variants of concern (VOCs), the third dose of booster ...
Yuwei Zhang +14 more
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Carbohydrate Immune Adjuvants in Subunit Vaccines [PDF]
Pharmaceutics, 2020 Modern subunit vaccines are composed of antigens and a delivery system and/or adjuvant (immune stimulator) that triggers the desired immune responses. Adjuvants mimic pathogen-associated molecular patterns (PAMPs) that are typically associated with infections.
Sahra Bashiri +3 more
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Frontiers in Immunology, 2023 Aeromonas hydrophila is a kind of zoonotic pathogen, which can cause bacterial septicemia in fish and bring huge economic losses to global aquaculture. Outer membrane proteins (Omps) are conserved antigens of Aeromonas hydrophila, which can be developed ...
Minying Zhang +19 more
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Acute retinal necrosis following recombinant subunit varicella-zoster virus vaccine
American Journal of Ophthalmology Case Reports, 2020 Purpose: Previously, secondary prevention of herpes zoster required live-attenuated vaccination, which is contraindicated in immunocompromised populations.
Rebecca I. Chen +3 more
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Virology Journal, 2023 Background Pseudorabies (PR) (also called Aujeszky’s disease, AD) is a serious infectious disease affecting pigs and other animals worldwide. The emergence of variant strains of pseudorabies virus (PRV) since 2011 has led to PR outbreaks in China and a ...
Hong-liang Zhang +6 more
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Raising Expectations For Subunit Vaccine [PDF]
The Journal of Infectious Diseases, 2014 Multidose regimens are recommended for all prophylactic subunit vaccines. Recent findings from clinical trials of an human papillomavirus virus-like particle vaccine suggest that it may be possible to develop effective single-dose subunit vaccines.
John T, Schiller, Douglas R, Lowy
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Journal of General Virology, 1983 Conclusions The secondary and tertiary structures of the rabies virus spike G protein are important for its ability to induce VN antibodies and confer immunity to the host. For a subunit peptide vaccine to be as effective as the native spike G protein, it would appear that the amino acid sequence comprising the antigenic determinant for VN antibody ...
W H, Wunner +3 more
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Viral Subunits for Rabies Vaccination [PDF]
Nature, 1969 RECENT work with adenovirus1, Sindbis virus2 and the viruses causing influenza3, measles4, vesicular stomatitis5 and German measles6 has shown that subunits of the viruses can stimulate the production of neutralizing antibodies, and in some cases can be used as vaccines.
J, Crick, F, Brown
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Protection against feline leukemia by vaccination with a subunit vaccine [PDF]
Infection and Immunity, 1981 An effective vaccine against feline leukemia virus infection has been developed by the collection and concentration of tissue culture medium harvested from a tumor cell line. Lymphoid cells were grown to near saturation density in a normal growth medium and then transferred to a serum-free medium.
M G, Lewis, L E, Mathes, R G, Olsen
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