Results 91 to 100 of about 471,587 (292)

Molecular Approaches for Improving Subunit Vaccines against [PDF]

, 2013
Infection with Mycobacterium tuberculosis, the causative agent of Tuberculosis (TB), remains responsible for at least 1.5 million deaths annually. BCG is the only currently licensed anti-TB vaccine, however its protective efficacy varies between 0 and 80%
KAO, Fan
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Recombinant subunit vaccines for soil-transmitted helminths

, 2017
SUMMARYSoil-transmitted helminths (STHs) collectively infect one fourth of all human beings, and the majority of livestock in the developing world. These gastrointestinal nematodes are the most important parasites on earth with regard to their prevalence
JASON B. NOON, RAFFI V. AROIAN
core   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Vaccines against avian influenza in poultry

Вопросы вирусологии, 2017
The review presents the latest data about the types of vaccines against avian influenza that are used in current medical practice or are under development.
L. V. Kostina, A. D. Zaberezhnyy, T. V. Grebennikova, N. V. Antipova, T. I. Aliper, E. A. Nepoklonov   +5 more
doaj   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Understanding protein subunit COVID-19 vaccines [PDF]

Updated July 20, 2022What You Need to Know\u2022 Protein subunit COVID-19 vaccines contain pieces (proteins) of the virus that causes COVID-19; these proteins are called the \u201cspike protein.\u201d\u2022 Protein subunit COVID-19 vaccines also contain ...

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Herd immunity conferred by killed oral cholera vaccines in Bangladesh: a reanalysis.

, 2005
BACKGROUND: Decisions about the use of killed oral cholera vaccines, which confer moderate levels of direct protection to vaccinees, can depend on whether the vaccines also provide indirect (herd) protection when high levels of vaccine coverage are ...
Ali, Mohammad, Sack, David A., Emch, Michael, Holmgren, Jan, Holmgren, Jan,, Clemens, John D, Rao, Malla, von Seidlein, Lorenz, Yunus, Mohammad, Clemens, John D., Sack, David A   +10 more
core   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Research progress on Haemophilus parasuis vaccines

Frontiers in Veterinary Science
Haemophilus parasuis (HPS) is the causative agent of porcine Glässer’s disease, which has become prevalent in China in recent years. It is characterized by fibrinous polyserositis, arthritis, and meningitis, but often shows mixed infection with other ...
Yu Duan, Yue Hao, Huapeng Feng, Jianhong Shu, Yulong He   +4 more
doaj   +1 more source