Results 81 to 90 of about 79,320 (275)

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

A novel subunit vaccine based on Fiber1/2 knob domain provides full protection against fowl adenovirus serotype 4 and induces stronger immune responses than a Fiber2 subunit vaccine

Poultry Science
: Outbreaks of hepatitis-hydropericardium syndrome (HHS) caused by fowl adenovirus serotype 4 (FAdV-4) have resulted in huge economic losses to the poultry industry in China since 2015.
Shuaifeng Liu, Xiaofeng Dong, Baishi Lei, Wuchao Zhang, Xiangqin Wang, Wanzhe Yuan, Kuan Zhao   +6 more
doaj   +1 more source

Expression of cholera toxin B subunit in Saccharomyces cerevisiae [PDF]

Cholera toxin, secreted by Vibrio cholerae, consists of A and B subunits. Cholera toxin B subunit (CTB) is used in many scientific research. It has already been expressed in several bacterial and plant systems.
ارزنلو, محسن, آهنگرزاده رضایی, محمد, زواران حسینی, احمد, توچیکوبو, کونیو, شاهرخی, نادر, یاسودا, یوکو, رضایی, عباس   +6 more
core  

Molecular Approaches for Improving Subunit Vaccines against [PDF]

, 2013
Infection with Mycobacterium tuberculosis, the causative agent of Tuberculosis (TB), remains responsible for at least 1.5 million deaths annually. BCG is the only currently licensed anti-TB vaccine, however its protective efficacy varies between 0 and 80%
KAO, Fan
core  

Herd immunity conferred by killed oral cholera vaccines in Bangladesh: a reanalysis.

, 2005
BACKGROUND: Decisions about the use of killed oral cholera vaccines, which confer moderate levels of direct protection to vaccinees, can depend on whether the vaccines also provide indirect (herd) protection when high levels of vaccine coverage are ...
Ali, Mohammad, Sack, David A., Emch, Michael, Holmgren, Jan, Holmgren, Jan,, Clemens, John D, Rao, Malla, von Seidlein, Lorenz, Yunus, Mohammad, Clemens, John D., Sack, David A   +10 more
core   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Efficacy, Safety, and Immunogenicity of Subunit Respiratory Syncytial Virus Vaccines: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Vaccines
Background: Respiratory syncytial virus (RSV) is garnering increasing attention, with a growing number of subunit RSV vaccines under active clinical investigation. However, comprehensive evidence is limited.
Yuhang Wu, Yuqiong Lu, Yuwei Bai, Bingde Zhu, Feng Chang, Yun Lu   +5 more
doaj   +1 more source

Role of fused Mycobacterium tuberculosis immunogens and adjuvants in modern tuberculosis vaccines

Frontiers in Immunology, 2014
Several approaches have been developed to improve or replace the only available vaccine for tuberculosis (TB), BCG (Bacille Calmette Guerin). The development of subunit protein vaccines is a promising strategy because it combines specificity and safety ...
Ana Paula eJunqueira-Kipnis, Lázaro Moreira Marques Neto, André eKipnis   +2 more
doaj   +1 more source

Plant-Based Vaccines in Combat against Coronavirus Diseases

, 2022
Coronavirus (CoV) diseases, including Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS) have gained in importance worldwide, especially with the current COVID-19 pandemic caused by SARS-CoV-2.
Tomasz Pniewski, Benita Ortega-Berlanga
core   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source