Results 71 to 80 of about 79,320 (275)

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

CHO Cell-Produced Truncated Bovine Ephemeral Fever Virus Glycoprotein as a Promising Subunit Vaccine Candidate for Cattle

Vaccines
Background/Objectives: Bovine ephemeral fever (BEF) is a significant disease affecting the cattle industry. The current control strategy for BEF in the field primarily relies on inactivated vaccines.
Huan-Yu Hsu, Shu-Ju Yeh, Chi-Chih Chen, Guan-Ming Ke   +3 more
doaj   +1 more source

Delivery of subunit vaccines in maize seed

Journal of Controlled Release, 2002
The use of recombinant gene technologies by the vaccine industry has revolutionized the way antigens are generated, and has provided safer, more effective means of protecting animals and humans against bacterial and viral pathogens. Viral and bacterial antigens for recombinant subunit vaccines have been produced in a variety of organisms.
Lamphear, Barry J, Streatfield, Stephen J, Jilka, Joseph M, Brooks, Christopher A, Barker, Donna K, Turner, Debra D, Delaney, Donna E, Garcia, Martin, Wiggins, Barry, Woodard, Susan L, Hood, Elizabeth E, Tizard, Ian R, Lawhorn, Bruce, Howard, John A   +13 more
openaire   +2 more sources

Maternal Immunization Using a Protein Subunit Vaccine Mediates Passive Immunity against Zaire ebolavirus in a Murine Model

, 2022
The Ebola virus has caused outbreaks in Central and West Africa, with high rates of morbidity and mortality. Clinical trials of recombinant virally vectored vaccines did not explicitly include pregnant or nursing women, resulting in a gap in knowledge of
Lieberman, Michael M., Ball, Aquena H., Lehrer, Axel T., Michael M. Lieberman, Aquena H. Ball, Axel T. Lehrer, Caitlin A. Williams, Williams, Caitlin A., Teri Ann S. Wong, Wong, Teri Ann S.   +9 more
core   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

Animal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng, Xuyan Xiang, Xinyu Qi, Hanrong Zhou, Peiyu Xiao, Fandan Meng, Tongqing An, Haiwei Wang   +7 more
wiley   +1 more source

Potential protective advantage of the protein-subunit SARS-CoV-2 vaccines, MVC-CoV1901 and NVX-CoV2373, in patients with rituximab-treated immune-mediated inflammatory diseases: Real-world evidence

Journal of the Formosan Medical Association
Since the COVID-19 pandemic, patients with immune-mediated inflammatory diseases (IMID) are recommended to receive SARS-CoV-2 vaccinations to reduce complications following COVID-19 infection.
Pei-Hsinq Lai, Ting-Yuan Lan, Cheng-Hsun Lu, Song-Chou Hsieh   +3 more
doaj   +1 more source

Determinants of Antibody Response to SARS-CoV-2 Vaccines in Liver Transplant Recipients: The Role of Immunosuppression Reduction

, 2022
Liver transplant recipients on chronic immunosuppression show an attenuated antibody response after SARS-CoV-2 vaccination. Adjusting immunosuppressants during vaccination remains debated.
Cheng, Chih-Hsien, Gu, Po-Wen, Wu, Ting-Jung, Huang, Chung-Guei, Yin Lai, Jin-Chiao Lee, Ting-Jung Wu, Tsung-Han Wu, Kun-Ming Chan, Lee, Chen-Fang, Chen-Fang Lee, Hung, Hao-Chien, Wu, Tsung-Han, Po-Wei Huang, Hao-Chien Hung, Wei-Chen Lee, Lee, Wei-Chen, Po-Wen Gu, Lai, Yin, Chih-Hsien Cheng, Chou, Hong-Shiue, Chan, Kun-Ming, Lee, Jin-Chiao, Wang, Yu-Chao, Hong-Shiue Chou, Huang, Po-Wei, Yu-Chao Wang, Chung-Guei Huang   +27 more
core   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Review Review Review: Protein Subunit and DNA Vaccines Key Research, Development & Future Directions

RADS Journal of Biological Research & Applied Science
Objective  To analyze the advancements, difficulties, and potential of DNA and protein subunit vaccines, with an emphasis on manufacturing capabilities, safety, and effectiveness, and to gauge their influence on upcoming vaccine studies ...
Hafiz Mirza Muhammad Shahab
doaj   +2 more sources

The development of contraceptive vaccines

, 2002
The use of vaccination as a means of controlling fertility was established during the last decade with the publication of a successful Phase II trial demonstrating the efficacy of this approach to family planning.
Delves, PJ
core