Results 71 to 80 of about 471,587 (292)

Review Review Review: Protein Subunit and DNA Vaccines Key Research, Development & Future Directions

open access: yesRADS Journal of Biological Research & Applied Science
Objective  To analyze the advancements, difficulties, and potential of DNA and protein subunit vaccines, with an emphasis on manufacturing capabilities, safety, and effectiveness, and to gauge their influence on upcoming vaccine studies ...
Hafiz Mirza Muhammad Shahab
doaj   +2 more sources

Potential protective advantage of the protein-subunit SARS-CoV-2 vaccines, MVC-CoV1901 and NVX-CoV2373, in patients with rituximab-treated immune-mediated inflammatory diseases: Real-world evidence

open access: yesJournal of the Formosan Medical Association
Since the COVID-19 pandemic, patients with immune-mediated inflammatory diseases (IMID) are recommended to receive SARS-CoV-2 vaccinations to reduce complications following COVID-19 infection.
Pei-Hsinq Lai   +3 more
doaj   +1 more source

Fc-Mediated E2-Dimer Subunit Vaccines of Atypical Porcine Pestivirus Induce Efficient Humoral and Cellular Immune Responses in Piglets

open access: yes, 2021
Congenital tremor (CT) type A-II in piglets is caused by an emerging atypical porcine pestivirus (APPV), which is prevalent in swine herds and a serious threat to the pig production industry.
Shudan Liu   +4 more
core   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang   +11 more
wiley   +1 more source

A novel subunit vaccine based on Fiber1/2 knob domain provides full protection against fowl adenovirus serotype 4 and induces stronger immune responses than a Fiber2 subunit vaccine

open access: yesPoultry Science
: Outbreaks of hepatitis-hydropericardium syndrome (HHS) caused by fowl adenovirus serotype 4 (FAdV-4) have resulted in huge economic losses to the poultry industry in China since 2015.
Shuaifeng Liu   +6 more
doaj   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

open access: yesAdvanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun   +18 more
wiley   +1 more source

Expression of cholera toxin B subunit in Saccharomyces cerevisiae [PDF]

open access: yes
Cholera toxin, secreted by Vibrio cholerae, consists of A and B subunits. Cholera toxin B subunit (CTB) is used in many scientific research. It has already been expressed in several bacterial and plant systems.
ارزنلو, محسن   +6 more
core  

Improving cellular cancer vaccines [PDF]

open access: yes, 2010
Immunization with cancer cells is of great demand in anti-cancer therapy. However, current cellular vaccines are inefficient and there are questions regarding their overall safety. We report a simple and straightforward approach for improving of cellular
Petr Lokhov
core  

Acknowledgment to Reviewers of Vaccines in 2020

open access: yes, 2021
Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Vaccines maintains its standards for the high quality of its published papers [...
Vaccines Editorial Office Vaccines Editorial Office
core   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang   +5 more
wiley   +1 more source

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