Results 71 to 80 of about 265,224 (289)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Building top management muscle in a slow growth environment: How different is better at Greyhound Financial Corporation [PDF]

, 1992
The turbulence experienced in the 1980s in the U.S. business environment has led to something of a motivational crisis among corporate managers. Increased competition, budget constraints, and changing demographics are forcing companies into adopting ...
Griffith, Terri L., Northcraft, Gregory B., Shalley, Christina E.   +2 more
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

The Impact of Succession Planning on Enhancing Organizational Citizenship Behavior: A Field Study at Tikrit University

Tikrit Journal of Administrative and Economic Sciences
The study aims to determine the extent to which succession planning contributes to enhancing organizational citizenship behavior at Tikrit University.
Nassr Husain Ali Aljnabi
doaj   +1 more source

Succession Planning for Managers in the Organization: A Case Study of the Ports and Maritime Organization [PDF]

Iranian Evolutionary Educational Psychology Journal, 2023
Succession planning involves a deliberate and systematic organization's effort to ensure the continuity of leadership in crucial roles, retain and nurture intellectual and knowledge assets for the future, and promote individual progress. Research studies
Mahmoud Saberi, Mahmoud Sabahizadeh, Kolsum Nami, Younes Daryoush   +3 more
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Employee Training and Succession Planning of Selected Deposit Money Banks in Abia State, Nigeria

SEISENSE Journal of Management, 2019
Purpose- This study investigates the relationship between employee training and succession planning in deposit money banks in Abia State using cross-sectional survey. Ten deposit money banks were surveyed using simple random sampling technique.  Design/
Edeh Ogbu Friday
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

SUCCESSION PLANNING FOR ORGANISATIONAL SURVIVAL: CHALLENGES AND RECOMMENDATIONS

Journal of Business Management and Accounting
Succession planning is an important component of organisational strategy because it assures leadership continuity and preserves institutional knowledge.
Muhamad ‘Abdin Syakirin Muhamad Azmi, Muhammad Alif Asyraf Ibrahim, Muhammad Shukry Hakimi Mohd Shukor, Abdul Amir Ikhwan Abdul Rahim, Fadilah Puteh, Alia Nadhirah Ahmad Kamal   +5 more
doaj   +1 more source

Corporate Governance and Management Succession in Family Businesses [PDF]

Family businesses carry the weight of economic wealth creation in most economies. In the U.S. alone, family businesses account for 80 to 90 percent of the 18-million business enterprises in the United States, and 50 percent of the employment and GNP.
John E. Butler, Phillip Phan, Soo Hoon Lee   +2 more
core