Results 51 to 60 of about 265,224 (289)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

National succession planning framework for children's services section two: resources [PDF]

open access: yes, 2010
"This section provides a range of materials to support use of section one of the national succession planning framework for children’s services" - Page ...

core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

PENGEMBANGAN MODEL KONSEPTUAL TENTANG KETERKAITAN PARA PELAKU DENGAN KELUASAN PERENCANAAN SUKSESI PADA PERUSAHAAN KELUARGA

open access: yesBenefit Jurnal Manajemen dan Bisnis, 2008
This seminal article discusses the basic concept of succession planning in family business. Family business succession has been a central subject in fsmily business research since it only has small satisfaction number of generation shifts.
Mugi Harsono
doaj  

Role of Female Successors in Family Business Innovation: Some Insights From the Largest Matrilineal Muslim Society

open access: yesSAGE Open, 2023
This study was conducted to examine innovation and succession planning of some Minangkabau family business using the institutional logic approach. It is important to note that the Minangkabau is completely a Muslim society in Indonesia and one of the ...
Donard Games, Dessy Kurnia Sari
doaj   +1 more source

Helping Organizations Achieve Successful Leadership Transitions [PDF]

open access: yes, 2009
Outlines issues nonprofits face during leadership transitions, and provides guidance for funders on supporting succession planning, executive transition management programs, interim executive directors, and leadership development for younger ...

core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

How are Companies Engaging Employees in the Succession Planning Process, and What are the Potential Benefits or Concerns Related to Increased Transparency? [PDF]

open access: yes, 2017
[Excerpt] With today’s movement for a more transparent employee experience in the workplace, it is important that companies engage in succession planning whereby employees are more involved.
Manjarrez, Daniel, Zhu, Julia
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Connecting Family Protocol and Family Council to Perceived Succession Success in Family Businesses through Management Succession Planning

open access: yesManagement Analysis Journal
The aim of the research is to identify the effect of family protocol and family council toward perceived success of succession though management succession planning mediation.
Jennifer Alberta Guntoro   +1 more
doaj   +1 more source

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