Results 51 to 60 of about 265,224 (289)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
National succession planning framework for children's services section two: resources [PDF]
"This section provides a range of materials to support use of section one of the national succession planning framework for children’s services" - Page ...
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
This seminal article discusses the basic concept of succession planning in family business. Family business succession has been a central subject in fsmily business research since it only has small satisfaction number of generation shifts.
Mugi Harsono
doaj
This study was conducted to examine innovation and succession planning of some Minangkabau family business using the institutional logic approach. It is important to note that the Minangkabau is completely a Muslim society in Indonesia and one of the ...
Donard Games, Dessy Kurnia Sari
doaj +1 more source
Helping Organizations Achieve Successful Leadership Transitions [PDF]
Outlines issues nonprofits face during leadership transitions, and provides guidance for funders on supporting succession planning, executive transition management programs, interim executive directors, and leadership development for younger ...
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
How are Companies Engaging Employees in the Succession Planning Process, and What are the Potential Benefits or Concerns Related to Increased Transparency? [PDF]
[Excerpt] With today’s movement for a more transparent employee experience in the workplace, it is important that companies engage in succession planning whereby employees are more involved.
Manjarrez, Daniel, Zhu, Julia
core +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The aim of the research is to identify the effect of family protocol and family council toward perceived success of succession though management succession planning mediation.
Jennifer Alberta Guntoro +1 more
doaj +1 more source

