Results 31 to 40 of about 218,507 (292)

Succinate/IL-1β Signaling Axis Promotes the Inflammatory Progression of Endothelial and Exacerbates Atherosclerosis

open access: yesFrontiers in Immunology, 2022
Inflammation is an important driver of atherosclerosis. Succinate is a new extracellular inflammatory alarm released by activated macrophages. Succinate is sensed by succinate receptor 1 (Sucnr1) and then transferred to effector cells.
Jingwen Xu   +9 more
semanticscholar   +1 more source

Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein

open access: yesEMBO Journal, 2022
Influenza virus infection causes considerable morbidity and mortality, but current therapies have limited efficacy. We hypothesized that investigating the metabolic signaling during infection may help to design innovative antiviral approaches.
A. Guillon   +25 more
semanticscholar   +1 more source

NADES Compounds Identified in Hypoxis hemerocallidea Corms during Dormancy

open access: yesPlants, 2022
Soaking Hypoxis hemerocallidea corms in distilled water improved the propagation and development of cormlets, suggesting the potential leaching-out of inhibitory chemical compounds.
Motiki M. Mofokeng   +5 more
doaj   +1 more source

Succinate dehydrogenase.

open access: yesAdvances in Enzymology and Related Subjects, 2020
A heterotetrameric enzyme complex found in the inner mitochondrial membrane. This protein complex catalyzes the oxidation of succinate and reduction of ubiquinone and plays a role in both the citric acid cycle and the electron transport chain.
T. Singer, E. Kearney, W. Kenney
semanticscholar   +1 more source

Experimental substantiation of permeabilized hepatocytes model for investigation of mitochondria in situ respiration [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2015
To verify experimentally the model of permeabilized hepatocytes, the degree of cell permeability was assessed using trypan blue and polarographycally determined cell respiration rate upon succinate (0.35 mM) and α-ketoglutarate (1 mM) oxidation ...
V. M. Merlavsky   +3 more
doaj   +1 more source

Visualization and Quantification of Genetically Adapted Microbial Cells During Preculture

open access: yesFrontiers in Microbiology, 2021
As culture history is known to affect the length of the lag phase and microbial cell growth, precultures are often grown in the same medium as the main culture for physiological adaptation and to reduce a prolonged lag time in some microbial cells.
Hyun Ju Kim   +2 more
doaj   +1 more source

Polylactide (PLA) and Its Blends with Poly(butylene succinate) (PBS): A Brief Review

open access: yesPolymers, 2019
Polylactide (PLA), poly(butylene succinate) (PBS) and blends thereof have been researched in the last two decades due to their commercial availability and the upcoming requirements for using bio-based chemical building blocks.
S. Su   +3 more
semanticscholar   +1 more source

Vinpocetine Ameliorates Metabolic-Syndrome-Associated Bladder Overactivity in Fructose-Fed Rats by Restoring Succinate-Modulated cAMP Levels and Exerting Anti-Inflammatory Effects in the Bladder Detrusor Muscle

open access: yesBiomedicines, 2022
Succinate and its receptor, the G protein-coupled receptor 91 (GPR91), have pathological implications in metabolic syndrome (MetS) and its associated bladder dysfunction, particularly in decreasing bladder cAMP levels and promoting proinflammation. Using
Wei-Chia Lee   +5 more
doaj   +1 more source

Immunometabolites Drive Bacterial Adaptation to the Airway

open access: yesFrontiers in Immunology, 2021
Pseudomonas aeruginosa and Staphylococcus aureus are both opportunistic pathogens that are frequently associated with chronic lung infections. While bacterial virulence determinants are critical in initiating infection, the metabolic flexibility of these
Kira L. Tomlinson   +2 more
doaj   +1 more source

Elevated plasma succinate levels are linked to higher cardiovascular disease risk factors in young adults

open access: yesCardiovascular Diabetology, 2021
Background Succinate is produced by both host and microbiota, with a key role in the interplay of immunity and metabolism and an emerging role as a biomarker for inflammatory and metabolic disorders in middle-aged adults.
Francisco J. Osuna-Prieto   +17 more
semanticscholar   +1 more source

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