Results 31 to 40 of about 215,979 (293)
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
Nature, 2014 Ischaemia-reperfusion injury occurs when the blood supply to an organ is disrupted and then restored, and underlies many disorders, notably heart attack and stroke.
Edward T. Chouchani +28 more
semanticscholar +1 more source
3,4-Diaminopyridinium hydrogen succinate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 في مركب العنوان، C(5)H(8)N(3) (+) ·C(4)H(5)O(4) (-)، يتم بروتنة ذرة البيريدين N من 3،4 -ديامينو- بيريدين مول- إيكول. تشارك ذرة N البروتونية في رابطة هيدروجينية N- H-O إلى ذرة سكسينات O من أنيون سكسينات منزوع البروتونات بشكل فردي. ترتبط كل من المجموعتين الأمينيتين بذرات O لمجموعتين مختلفتين من مجموعات السكسينات.
Hoong‐Kun Fun, Kasthuri Balasubramani
openaire +3 more sources
Cancer-derived extracellular succinate: a driver of cancer metastasis
Journal of Biomedical Sciences, 2022 Succinate is a tricarboxylic acid (TCA) cycle intermediate normally confined to the mitochondrial matrix. It is a substrate of succinate dehydrogenase (SDH). Mutation of SDH subunits (SDHD and SDHB) in hereditary tumors such as paraganglioma or reduction
C. Kuo, Jing-Yiing Wu, Kenneth K. Wu
semanticscholar +1 more source
Mitochondrial respiration after combined action of dehydration and low temperature in pea seedlings
Biologia Plantarum, 2019 The impact of the individual and combined action of dehydration and low temperature on the respiratory activity of mitochondria isolated from epicotyls of pea (Pisum sativum L.) seedlings was investigated. These organelles were isolated immediately after
I.P. Generozova +2 more
doaj +1 more source
Cell Reports, 2019 We demonstrated the metabolic benefits of Parabacteroides distasonis (PD) on decreasing weight gain, hyperglycemia, and hepatic steatosis in ob/ob and high-fat diet (HFD)-fed mice. Treatment with live P.
Kai Wang +11 more
semanticscholar +1 more source
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Nature Communications, 2021 Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear.
Xiao-Hui Wang +12 more
semanticscholar +1 more source
Metabolites, 2023 Total parenteral nutrition (TPN) is life-saving therapy for the pediatric patients with intestinal failure (IF) who cannot tolerate enteral nutrition (EN).
Junkai Yan +4 more
doaj +1 more source
Molecules, 2023 Tetrahydrocurcumin, the most abundant curcumin transformation product in biological systems, can potentially be a new alternative therapeutic agent with improved anti-inflammatory activity and higher bioavailability than curcumin.
Yisett González +8 more
doaj +1 more source
Molecules and Cells, 2019 Macrophages form a major cell population in the tumor microenvironment. They can be activated and polarized into tumor-associated macrophages (TAM) by the tumor-derived soluble molecules to promote tumor progression and metastasis.
Jing-Yiing Wu +15 more
semanticscholar +1 more source
Biomedicines, 2022 Research focused on succinate dehydrogenase (SDH) and its substrate, succinate, culminated in the 1950s accompanying the rapid development of research dedicated to bioenergetics and intermediary metabolism.
Paule Bénit +6 more
doaj +1 more source