Results 41 to 50 of about 162,568 (118)
Utilization of fumarate by sulfur-reducing bacteria Desulfuromonas sp.
Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2016 The main goal of the work was to study the utilization of fumarate by sulfur-reducing bacteria Desulfuromonas sp. under different growth conditions and accumulation of hydrogen sulfide by bacteria in the media with sulfur and different electron donors ...
O. Сhayka +3 more
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Biomolecules, 2023 Uterine endometrial cancer (UEC) is an estrogen-related tumor. Succinate and heme metabolism play important roles in the progression of multiple tumors.
Jia-Jing Lu +9 more
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Mechanisms of intestinal dysbiosis: new insights into tuft cell functions
Gut MicrobesSymbiosis between the host and intestinal microbial communities is essential for human health. Disruption in this symbiosis is linked to gastrointestinal diseases, including inflammatory bowel diseases, as well as extra-gastrointestinal diseases ...
Nathalie Coutry +3 more
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Frontiers in Immunology, 2023 Hepatocellular carcinoma (HCC) is the most prevalent primary liver malignancy worldwide and is associated with a poor prognosis. Sophisticated molecular mechanisms and biological characteristics need to be explored to gain a better understanding of HCC ...
Wenhui Zhang +3 more
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A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions
eLife, 2023 Using embryonic stem cells (ESCs) in regenerative medicine or in disease modeling requires a complete understanding of these cells. Two main distinct developmental states of ESCs have been stabilized in vitro, a naïve pre-implantation stage and a primed ...
Damien Detraux +7 more
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Hypoxia/Reoxygenation-Induced Mitochondrial Reverse Electron Transfer: A Targetable Mechanism to Enhance Radiosensitivity in Non-Small Cell Lung Cancer [PDF]
Antioxidants (Basel)Hypoxia-induced radioresistance remains a major obstacle in non-small cell lung cancer (NSCLC) radiotherapy. This study investigates whether artificially activating mitochondrial reverse electron transfer (RET) can enhance radiosensitivity in NSCLC by ...
Hu C +8 more
europepmc +2 more sources
Mitochondrial complex II and reactive oxygen species in disease and therapy
Redox Report, 2020 Increasing evidence points to the respiratory Complex II (CII) as a source and modulator of reactive oxygen species (ROS). Both functional loss of CII as well as its pharmacological inhibition can lead to ROS generation in cells, with a relevant impact ...
Katerina Hadrava Vanova +3 more
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Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages
Metabolites, 2020 Immunometabolism revealed the crucial role of cellular metabolism in controlling immune cell phenotype and functions. Macrophages, key immune cells that support progression of numerous inflammatory diseases, have been well described as undergoing vast ...
Karl J. Harber +7 more
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Frontiers in Aging, 2022 Blue light (BL) is becoming increasingly prevalent in artificial illumination, raising concerns about its potential health hazard to humans. In fact, there is evidence suggesting that acute BL exposure may lead to oxidative stress and death of retinal ...
Jun Yang +10 more
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Effect of propionate on lipogenesis in adipose tissue
Journal of Lipid Research, 1967 The metabolism of propionate in adipose tissue and its effect on lipogenesis was investigated. Fasting induced changes in propionate metabolism of adipose tissue, drastically reducing higher fatty acid synthesis and increasing glycerideglyerol formation ...
L. Reshef, J. Niv, B. Shapiro
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