Results 11 to 20 of about 433,622 (361)

Succinate dehydrogenase. [PDF]

Advances in Enzymology and Related Subjects, 2020
A heterotetrameric enzyme complex found in the inner mitochondrial membrane. This protein complex catalyzes the oxidation of succinate and reduction of ubiquinone and plays a role in both the citric acid cycle and the electron transport chain.
T. Singer, E. Kearney, W. Kenney
semanticscholar   +4 more sources

A dispensable paralog of succinate dehydrogenase subunit C mediates standing resistance towards a subclass of SDHI fungicides in Zymoseptoria tritici [PDF]

bioRxiv, 2019
Succinate dehydrogenase inhibitor (SDHI) fungicides are widely used for the control of a broad range of fungal diseases. This has been the most rapidly expanding fungicide group in terms of new molecules discovered and introduced for agricultural use ...
D. Steinhauer, Marie Salat, R. Frey, A. Mosbach, Torsten Luksch, Dirk Balmer, R. Hansen, Stephanie Widdison, Grace Logan, R. Dietrich, G. Kema, S. Bieri, H. Sierotzki, S. Torriani, G. Scalliet   +14 more
semanticscholar   +2 more sources

Succinate Dehydrogenase Complex: An Updated Review.

Archives of Pathology & Laboratory Medicine, 2018
Succinate dehydrogenase (SDH) is uniquely tasked with a dual role in the essential energy-producing processes of a cell. Although SDH subunits and assembly factors form part of the same enzyme complex, mutations in their respective genes lead to ...
M. R. H. A. Rasheed, G. Tarján
semanticscholar   +2 more sources

Succinate dehydrogenase--a comparative review [PDF]

Microbiological Reviews, 1981
L, Hederstedt, L, Rutberg
openaire   +4 more sources

Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels*

Journal of Biological Chemistry, 2016
Metabolic reprogramming is emerging as a hallmark of the innate immune response, and the dynamic control of metabolites such as succinate serves to facilitate the execution of inflammatory responses in macrophages and other immune cells. Immunoresponsive
Thekla Cordes, M. Wallace, A. Michelucci, Ajit S. Divakaruni, Sean C. Sapcariu, Carole Sousa, H. Koseki, P. Cabrales, A. Murphy, Karsten Hiller, Christian M. Metallo   +10 more
semanticscholar   +2 more sources

Synchronous Succinate Dehydrogenase Subunit B (SDHB)-Deficient Gallbladder Paraganglioma and Periduodenal Well-Differentiated Neuroendocrine Tumor: A Case Report. [PDF]

Cureus
Lee S, Paz M, Gupta A, Schat R, Woehrle S, Park BU.   +5 more
europepmc   +3 more sources

Hereditary pheochromocytoma/paraganglioma syndrome with a novel mutation in the succinate dehydrogenase subunit B gene in a Japanese family: two case reports

Journal of Medical Case Reports, 2021
Background Pheochromocytoma and paraganglioma caused by succinate dehydrogenase gene mutations is called hereditary pheochromocytoma/paraganglioma syndrome.
Rei Hirose, Yuya Tsurutani, Chiho Sugisawa, Kosuke Inoue, Sachiko Suematsu, Maki Nagata, Naoki Hasegawa, Yukio Kakuta, Masato Yonamine, Kazuhiro Takekoshi, Noriko Kimura, Jun Saito, Tetsuo Nishikawa   +12 more
doaj   +1 more source

Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation

bioRxiv, 2021
Robust and effective T cell-mediated immune responses require the proper allocation of metabolic resources to sustain energetically costly processes like growth, proliferation, and cytokine production. Epigenetic control of the genome also governs T cell
Xuyong Chen, Benjamin D. Sunkel, Meng Wang, Siwen Kang, Tingting Wang, J. R. Gnanaprakasam, Lingling Liu, Teresa A. Cassel, D. Scott, Ana M. Muñoz-Cabello, J. López-Barneo, Jun J. Yang, A. Lane, G. Xin, Benjamin Z. Stanton, T. Fan, Ruoning Wang   +16 more
semanticscholar   +1 more source

TCA cycle tailoring facilitates optimal growth of proton-pumping NADH dehydrogenase-dependent Escherichia coli

Microbiology Spectrum, 2023
The bacterial lifestyle is plastic, requiring transcriptional, translational, and metabolic tailoring for survival. These dynamic cellular processes are energy intensive; therefore, flexible energetics is requisite for adaptive plasticity.
Nikita Goel, Stuti Srivastav, Arjun Patel, Akshay Shirsath, Tushar Ranjan Panda, Malay Patra, Adam M. Feist, Amitesh Anand   +7 more
doaj   +1 more source

Functional succinate dehydrogenase deficiency is a common adverse feature of clear cell renal cancer

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance This study demonstrates that underexpression of succinate dehydrogenase (SDH) subunits resulting in accumulation of oncogenic succinate is a common, adverse, epigenetic modulating feature in clear cell renal cell carcinoma (ccRCC), during ...
R. Aggarwal, Rebecca A. Luchtel, V. Machha, Alexander Tischer, Y. Zou, K. Pradhan, Nadia Ashai, N. Ramachandra, J. Albanese, Jung-in Yang, Xiaoyang Wang, Srinivas Aluri, Shanisha A. Gordon, A. Aboumohamed, B. Gartrell, S. Hafizi, J. Pullman, N. Shenoy   +17 more
semanticscholar   +1 more source