Results 31 to 40 of about 426,215 (376)

Effects of caloric restriction and ketogenic diet on renal fibrosis after ischemia/reperfusion injury

Heliyon, 2023
The beneficial effects of caloric restriction (CR) and a ketogenic diet (KD) have been previously shown when performed prior to kidney injury. We investigated the effects of CR and KD on fibrosis development after unilateral kidney ischemia/reperfusion ...
E.I. Yakupova, D.S. Semenovich, P.A. Abramicheva, L.D. Zorova, I.B. Pevzner, N.V. Andrianova, V.A. Popkov, V.N. Manskikh, A.D. Bocharnikov, Y.A. Voronina, D.B. Zorov, E.Y. Plotnikov   +11 more
doaj   +1 more source

Succinate Dehydrogenase Deficiency

Archives of Pathology & Laboratory Medicine, 2000
Abstract Background.—Partial succinate dehydrogenase deficiency (15% to 50% of normal reference enzyme activity) in skeletal muscle causes mitochondrial myopathy with various symptoms, for example, brain involvement, cardiomyopathy, and/or exercise intolerance.
Reid R. Heffner, Georgirene D. Vladutiu
openaire   +3 more sources

The CreC regulator of Escherichia coli, a new target for metabolic manipulations [PDF]

, 2015
The CreBC (carbon source-responsive) two-component regulation system of Escherichia coli affects a number of functions, including intermediary carbon catabolism.
Cabrera Gomez, José Gregorio, Godoy, Manuel Santiago, Nikel, Pablo Ivan, Pettinari, María Julia   +3 more
core   +1 more source

Mitochondrial disorders in neuromuscular pathology

Нервно-мышечные болезни, 2019
Introduction. With the advent of new drugs — analogues of mitochondrial metabolites, the widespread introduction into practice of research methods for assessing the function of mitochondria in patients with neurological pathology and other diseases ...
S. V. Kotov, O. P. Sidorova, E. V. Borodataya   +2 more
doaj   +1 more source

Computational prediction and experimental verification of the gene encoding the NAD � /NADP � - dependent succinate semialdehyde dehydrogenase in Escherichia coli [PDF]

, 2007
Although NAD -dependent succinate semialdehyde dehydrogenase activity was first described in Escherichia coli more than 25 years ago, the responsible gene has remained elusive so far.
Dennis Vitkup, Lifeng Chen, Tobias Fuhrer, Uwe Sauer   +3 more
core   +2 more sources

HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium [PDF]

, 2013
Background: While acute lung injury (ALI) contributes significantly to critical illness, it resolves spontaneously in many instances. The majority of patients experiencing ALI require mechanical ventilation.
Bonney, Megan, Borchers, Christoph H., Brodsky, Kelley, Eckle, Tobias, Eltzschig, Holger K., Han, Jun, Kominsky, Douglas J., Mariani, Thomas J., Mittelbronn, Michel Guy André, Packard, Thomas   +9 more
core   +3 more sources

Discovery of Pyrazine-Carboxamide-Diphenyl-Ethers as Novel Succinate Dehydrogenase Inhibitors via Fragment Recombination.

Journal of Agricultural and Food Chemistry, 2020
The discovery of novel succinate dehydrogenase inhibitors (SDHIs) has attracted great attention worldwide. Herein, a fragment recombination strategy was proposed to design new SDHIs by understanding the ligand-receptor interaction mechanism of SDHIs ...
Hua Li, Meng-Qi Gao, Yan Chen, Yu-Xia Wang, Xiao-Lei Zhu, Guangfu Yang   +5 more
semanticscholar   +1 more source

Over-representation of the G12S polymorphism of the SDHD gene in patients with MEN2A syndrome

Clinics, 2012
OBJECTIVE: To evaluate whether germline variants of the succinate dehydrogenase genes might be phenotypic modifiers in patients with multiple endocrine neoplasia type 2.
Nikoletta Lendvai, Miklos Tóth, Zsuzsanna Valkusz, Gabriella Bekő, Nikolette Szücs, Éva Csajbók, Péter Igaz, Balázs Kriszt, Balázs Kovács, Károly Rácz, Attila Patócs   +10 more
doaj   +1 more source

Determination of 19 Succinate Dehydrogenase Inhibitor Fungicides Pesticide Residues in Green Coffee by Quechers-Liquid Chromatography Tandem Mass Spectrometry

Liang you shipin ke-ji, 2023
This study establishes an analytical method for simultaneous determination of 19 Succinate dehydrogenase inhibitor fungicides pesticide residues in Green coffee by QuEChERS-Liquid chromatography tandem mass spectrometry.
MAO Jing-chun, WU Xu-dong, LUO Fa-mei, ZHOU Qin, PU Hong-jun, DENG Hong-yan, CHENG Long   +6 more
doaj   +1 more source

Breast cancer–associated macrophages promote tumorigenesis by suppressing succinate dehydrogenase in tumor cells

Science Signaling, 2020
Macrophage-secreted TGF-β promotes glycolysis in tumor cells to support angiogenesis and immunosuppression. TAMs reprogram tumor metabolism Macrophages in the tumor microenvironment [called tumor-associated macrophages (TAMs)] often support tumor growth ...
Valentí Gómez, T. Eykyn, R. Mustapha, F. Flores-Borja, Victoria Male, P. Barber, A. Patsialou, R. Green, Fani Panagaki, Chun W. Li, G. Fruhwirth, S. Ros, K. Brindle, T. Ng   +13 more
semanticscholar   +1 more source