Results 41 to 50 of about 2,827 (245)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

THERMAL BEHAVIOUR OF SUCCINIC ACID, SODIUM SUCCINATE AND ITS COMPOUNDS WITH SOME BIVALENT TRANSITIONS METAL IONS IN DYNAMIC N 2 AND CO ATMOSPHERES

Eclética Química, 2018
Thermal stability and thermal decomposition of succinic acid, sodium succinate and its compounds with Mn(II), Fe(II), Co(II),  Ni(II), Cu(II) and Zn(II) were investigated employing simultaneous thermogravimetry and differential thermal analysis (TG-DTA ...
Flávio Junior Caires, Liliane Spazzapam Lima, Cláudio Teodoro de Carvalho, Massao Ionashiro   +3 more
doaj   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Yttrium-succinates coordination polymers: Hydrothermal synthesis, crystal structure and thermal decomposition

, 2009
New polymeric yttrium-succinates, Y2(C4H4O4)3(H2O)4·6H2O and Y2(C4H4O4)3(H2O)2, have been synthesized, and their structures (solved by single crystal XRD) are compared with that of Y2(C4H4O4)3(H2O)2·H2O.
Mafra, Luís Miguel Monteiro, Amghouz, Zakariae, Rocha, João Carlos Matias Celestino Gomes da, Souhail, Badredine, Roces Fernández, Laura, García Menéndez, José Rubén, García-Granda, Santiago, Shi, Fha-Nian   +7 more
core   +1 more source

Photo‐Switchable Molecular Module Programming PET Biodegradation in Aquatic Environments

Advanced Functional Materials, EarlyView.
We address the plastic durability paradox by integrating an itaconic acid–derived pyrrolidone module into polymer backbones. Sunlight in water triggers Norrish Type I ring‐opening and hydrophilization, enabling rapid biodegradation into nontoxic minerals.
Mohammad Asif Ali, Jixin Zheng, Satoshi Wakai, Jie Liu, Hidetaka Nomaki, Misato Tsukatani, Noriyuki Isobe, Jingcheng Sang, Yuriko Aoki, Hideo Okamura, Daisuke Sasaki, Chiaki Ogino, Yuzo Yamazaki, Takashi Nishikaze, Kenji Takada, Maiko K. Okajima, Tatsuo Kaneko   +16 more
wiley   +1 more source

Sustainable and Multifunctional Natural Macromolecular Polymers for Aqueous Zn Metal Batteries

Advanced Materials, EarlyView.
We comprehensively review the structure‐function relationships and regulatory mechanism of natural macromolecular polymers in stabilizing zinc anodes at the microscopic and mesoscopic scales. The interactions among polymer structures, optimization strategies, and regulatory mechanisms are discussed systematically summarizing recent related research ...
Yunuo Shi, Bo Jiang, Jingcheng Zhang, Xiaodong Shao, Peixun Xiong, Lutong Shan, Shengyang Huang, Mengfang Liang, Mengyao Chang, Fangyan Liu, Wenwu Li, Baoyu Xia, Wei Ji, Ho Seok Park   +13 more
wiley   +1 more source

Metabolic activity of tree saps of different origin towards cultured human cells in the light of grade correspondence analysis and multiple regression modeling

Acta Societatis Botanicorum Poloniae, 2017
Tree saps are nourishing biological media commonly used for beverage and syrup production. Although the nutritional aspect of tree saps is widely acknowledged, the exact relationship between the sap composition, origin, and effect on the metabolic rate ...
Artur Wnorowski, Maciej Bilek, Kinga Stawarczyk, Michał Gostkowski, Marcin Olszewski, Magdalena Wójciak-Kosior, Ireneusz Sowa   +6 more
doaj   +1 more source

New Composites CP@AC Based on Lanthanide Succinates

, 2019
Composites derived from coordination polymers have been gathering great attention due to their singular properties and applications, especially catalysis and adsorption.
Guilherme C. Santos (6485234), Fausthon F. da Silva (3686545), Severino Alves Jr. (2264404), Carlos A. F. de Oliveira (3686548)   +3 more
core   +1 more source

Silk Fibroin Nanofiber–Immobilized Horseradish Peroxidase Enables Continuous Preparation of Injectable Hydrogels With Negligible Residual Enzyme for Drug Delivery

Advanced Materials Technologies, EarlyView.
Overcoming the immunogenicity challenges of enzyme‐mediated crosslinking, a flow‐through reactor utilizing SFNF‐HRP enables the continuous production of injectable hydrogels. This continuous platform ensures homogeneous crosslinking while minimizing residual HRP in the resulting hydrogels.
Ayari Miyawaki, Shinji Sakai
wiley   +1 more source

Open-Framework Cadmium Succinates with Interpenetrating Frameworks Formed by Tetrahedral [ClCd₄O₂₄] and [BrCd₄O₂₄] Clusters

, 2016
By carrying out a metathetic reaction between sodium succinate and CdCl2 or CdBr2 in an n-butanol−water mixture, two novel open-framework cadmium succinates, [Na3Cd5(C4H4O4)6Cl], I, and [Na3Cd5(C4H4O4)6Br], II, have been isolated. Both of these compounds
C. N. R. Rao (1363824), R. Vaidhyanathan (2952330), Srinivasan Natarajan (1655116)   +2 more
core   +2 more sources