Results 51 to 60 of about 2,827 (245)

Tailored Stereo‐Configuration of Crosslinkable Polyester‐Based Solid Polymer Electrolytes for All‐Solid‐State and Binder‐Free Li Metal Batteries

Advanced Science, EarlyView.
Variations in polymer conformations of unsaturated poly(n‐alkyl esters) driven by monomer‐level stereochemistry directly govern Li+ solvation structures in polymer host matrices. The synergistic strategies of polymer conformation control, UV‐induced interchain crosslinking, and end‐group fluorination are implemented for engineering advanced solid ...
Hyun Jun Song, Jeong Yoon Kim, Sungpyo Hong, Yong Hui Kim, Myeong Gyun Nam, Jeong‐Won Ho, Min Gi Kang, Hye Seon Kim, Chaeyeon Ha, Sang Uck Lee, Pil J. Yoo, Patrice Rannou   +11 more
wiley   +1 more source

Selenium-directed conjugate addition of amines to dimethyl 2-phenylseleno fumarate: Regio and diastereoselective synthesis of 2-phenylseleno-3-amino succinates

, 1997
Dimethyl 2-phenylseleno fumarate 1 acts as a strong Michael acceptor of amines, providing the corresponding 2-phenylseleno-3-amino succinates 2a and 2b in very high yields with complete regio-and good diastereoselectivity.
F. DOnofrio, G. Piancatelli, R. Margarita, M. Bella, MANGONI, ALFONSO, L. Parlanti   +5 more
core   +1 more source

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

Advanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li, Zengnan Wu, Yingrui Zhang, Shulang Chen, Yongning Lin, Shiyu Chen, Tong Xu, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +9 more
wiley   +1 more source

Nitroalkanes and Dimethyl Maleate as Source of 3-Alkyl Succinic Anhydrides and (E)-3-Alkylidene Succinic Anhydrides

, 2002
Nitroalkanes react with dimethyl maleate giving a tandem Michael addition/elimination of nitrous acid. The obtained (E)-2-alkylidene dimethyl succinates are: (i) reduced to the corresponding 2-alkyl dimethyl succinates which after hydrolysis produce 1,4 ...
Dennis Fiorini, BOSICA, Giovanna, Roberto Ballini, Giovanna Bosica, Paolo Righi, BALLINI, Roberto, FIORINI, Dennis   +6 more
core   +3 more sources

Carbanion Rearrangements. Collision-Induced Reactions of Enolate Negative Ions Derived From Dimethyl Succinates and Hexane-2,5-Dione

, 1987
Enolate ion MeOCOCHCH2CO2Me fragments through the intermediacy of two ion complexes [ MeOCO (CH2=CHCO2Me)] and [ MeO-(O=C=CHCH2CO2Me)]. The major fragmentations produce CH2=C=C( OMe )O-+HCO2Me and O=C=CH- CH=C( OMe ).
MJ Raftery, JH Bowie
core   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

Synthesis and characterization of novel poly(butylene succinate-co-2-methyl-1,3-propylene succinate)s

eXPRESS Polymer Letters, 2011
Poly(butylene succinate) (PBSu), poly(2-methyl-1,3-propylene succinate) (PMPSu), and PBSu-rich copolyesters were synthesized using an effective catalyst, titanium tetraisopropoxide.
doaj   +1 more source

Pediatric Erythromycins:  a Comparison of the Properties of Erythromycins A and B 2‘-Ethyl Succinates

, 2016
The antibiotic erythromycin A is generally administered to children as a suspension of the pro-drug erythromycin A 2‘-ethyl succinate. The success of the pro-drug depends on (a) elimination of the unacceptably bitter taste of free erythromycin, (b) its ...
Abdolreza Hassanzadeh (2473027), Gareth A. Morris (1333929), Jill Barber (1520668), Peter A. Gorry (2473024)   +3 more
core   +1 more source

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang, Wenhao Ma, Yi Zhou, Zhijie Wu, Pan Gao, Hongze Niu, Hongfei Tai, Tianyi Zhao, Zheyue Dong, Li Li, Yan Zhang, An Wang, Si Shen, Yueyang Li, Sifei Yu, Yan Peng, Wang Sheng, Xiaoyan Dong, Hua Pan, Kaibin Shi, Magdalena J. Koziol, Xiaobing Wu, Zaiqiang Zhang   +22 more
wiley   +1 more source

Enzymes involved in the anaerobic oxidation of n-alkanes: from methane to long-chain paraffins

Frontiers in Microbiology, 2013
Anaerobic microorganisms play key roles in the biogeochemical cycling of methane and non-methane alkanes. To date, there appear to be at least three proposed mechanisms of anaerobic methane oxidation (AOM). The first pathway is mediated by consortia of
Amy V. Callaghan
doaj   +1 more source