Results 61 to 70 of about 2,827 (245)

Novel coordination polymers of metal(II) succinates with 4-aminopyridine: Synthesis, spectroscopic, thermal, and fluorescent properties

, 2011
Four novel divalent transitional metal succinates (suc) with 4-aminopyridine (apy), [M(apy)2(H2O)2(?-suc) ]n [M = Ni (1), Co (2)] and [M(apy)2(H2O)(suc)] [M = Cu (3), Zn (4)] were synthesized and characterized by elemental analyses, IR spectroscopy, and ...
Demir, Selçuk, Selçuk Demir, Kaya, Günay, Günay Kaya   +3 more
core   +1 more source

Super‐Multiplexed Label‐Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation

Advanced Science, EarlyView.
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li, Xia Chen, Yujuan Qi, Chen Qiao, Qiuru Huang, Dan Zhao, Weiyi Qian, Li Di, Yi Shi, Xiangqi Hu, Yueyue Shao, Kehan Wang, Zhiyu Tang‐Yang, Hanzhi Zang, Yuwen Du, Anran Dong, Jinxiong Feng, Jiayun Chen, Ying Zheng, Xiaofang Tan, Xiaoyu Zhao, Zhonghua Shi, Bo Zheng, Jun Yu   +23 more
wiley   +1 more source

Pediatric erythromycins: A comparison of the properties of erythromycins A and B 2′-ethyl succinates

, 2006
The antibiotic erythromycin A is generally administered to children as a suspension of the pro-drug erythromycin A 2′-ethyl succinate. The success of the pro-drug depends on (a) elimination of the unacceptably bitter taste of free erythromycin, (b) its ...
Hassanzadeh, Abdolreza, Barber, Jill; id_orcid, Gorry, Peter A., Morris, Gareth A.; id_orcid   +3 more
core   +1 more source

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

Success of Succinates and Prospects for Their Use in Critical Conditions

Антибиотики и Химиотерапия
To date, preparations containing succinic acid (succinate) are widely known to specialists working in intensive care. Several such preparations have gained wide acclaim among anesthesiologists and resuscitators, namely: Reamberin, infusion solution — a ...
S. V. Sviridov, A. V. Butrov, V. V. Afanasyev, Yu. P. Orlov, A. Yu. Petrov   +4 more
doaj   +1 more source

Preparation and Performance of Hydroxypropyl Methylcellulose Esters of Substituted Succinates for in Vitro Supersaturation of a Crystalline Hydrophobic Drug

, 2016
We prepared hydroxypropyl methylcellulose (HPMC) esters of substituted succinates and examined their performance for improving the aqueous solubility of crystalline hydrophobic drugs in spray-dried dispersions (SDDs).
Ligeng Yin (1863133), Marc A. Hillmyer (1301541)   +1 more
core   +1 more source

Ion‐Driven Regulation of Ca2+ Flow by Ti/Zn Composite Activates ERK/MAPK Signaling and Maintains Mitochondrial Homeostasis to Promote Macrophage‐Mediated Bone Regeneration

Advanced Science, EarlyView.
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang, Qiyue Zhang, Yueyang Qiu, Haocheng Suo, Zengqian Liu, Bing Bai, Qiang Wang, Qing Zhou   +7 more
wiley   +1 more source

Open-framework cadmium succinates with interpenetrating frameworks formed by tetrahedral [ClCd₄O₂₄] and [BrCd₄O₂₄] clusters

, 2003
By carrying out a metathetic reaction between sodium succinate and CdCl2 or CdBr2 in an n-butanol-water mixture, two novel open-framework cadmium succinates, [Na3Cd5(C4H4O4)6Cl], I, and [Na3Cd5(C4H4O4)6Br], II, have been isolated. Both of these compounds
Natarajan, Srinivasan, Vaidhyanathan, R., Rao, C. N. R.   +2 more
core   +1 more source

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

Versatile transformations of hydrocarbons in anaerobic bacteria: substrate ranges and regio- and stereochemistry of activation reactions

Frontiers in Microbiology, 2015
Anaerobic metabolism of hydrocarbons proceeds either via addition to fumarate or by hydroxylation in various microorganisms, e.g. sulfate-reducing or denitrifying bacteria, which are specialized in utilizing n-alkanes or alkylbenzenes as growth ...
René eJarling, Simon eKühner, Eline eBasílio Janke, Andrea eGruner, Marta eDrozdowska, Bernard T. Golding, Ralf eRabus, Ralf eRabus, Heinz eWilkes, Heinz eWilkes   +9 more
doaj   +1 more source