Results 141 to 150 of about 78,749 (257)

Chemically stabilized subtilisins in peptide synthesis [PDF]

open access: yes, 2008
We have stabilized alcalaseTM and subtilisin Carlsberg (SC) against heat by chemical modification with ethylene glycol bis-succinimidyl succinate (EGNHS), a procedure not previously reported for subtilisins.
Colleary, Sandra, Ó Fágáin, Ciarán
core  

Protective Mechanism of Aqueous Extract From Ixeris sonchifolia in Myocardial Ischemia–Reperfusion Injury: Insights From Network Pharmacology and Experimental Validation

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
This study evaluated KDZ aqueous extract's therapeutic potential for MI/RI and investigated its mechanism. In a mouse MI/RI model, the aqueous extract mitigated injury and preserved cardiac function. Liquid chromatography‐mass spectrometry (LC–MS) identified eighty‐six components. Based on Compound‐target‐disease interaction network and KEGG enrichment
Xiaoxia Tian   +7 more
wiley   +1 more source

Dietary supplementation with succinic acid improves growth performance and flesh quality of adult Nile tilapia (Oreochromis niloticus) fed a high-carbohydrate diet

open access: yesAnimal Nutrition
To evaluate the effects of dietary supplementation with succinic acid on growth performance, flesh quality, glucose, and lipid metabolism of Nile tilapia (Oreochromis niloticus) fed a high-carbohydrate diet (HCD), five iso-nitrogenous and iso-lipidic ...
Manxia Cao   +8 more
doaj   +1 more source

Lactuca sativa L. losses and wastes as a source of biobased ingredients

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 6, Page 3577-3591, April 2026.
Abstract BACKGROUND The growing global population and increasing consumer focus on healthy eating challenge the agricultural sector to ensure both sustainable food production and safety. Lettuce (Lactuca sativa Mill.), the most cultivated leafy vegetable worldwide, can lose up to 40% of its weight during processing.
Joana PB Rodrigues   +8 more
wiley   +1 more source

Multiomics Research Strategies in Cancer: A Growing and Innovative Field

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This review highlights multiomics strategies in cancer research, focusing on integration methods from genomics to microbiomics. Using colorectal cancer as a key example, it discusses biomarker discovery, data integration via deep learning, and the roles of single‐cell and spatial omics.
Zhenhua Du   +8 more
wiley   +1 more source

Butia catarinensis as a Sustainable Ingredient in Brazilian Mead: Chemical Properties, Volatile Composition, Sensory Profile and Consumer Acceptance

open access: yesJournal of Food Science, Volume 91, Issue 4, April 2026.
ABSTRACT Mead is a fermented alcoholic beverage traditionally produced with honey, water, and yeast, with possible variations through the addition of fruits or spices. Butia catarinensis is a native Brazilian fruit with high sensory appeal, traditionally used in cachaça but underexplored in fermented beverages.
Rodrigo Ribeiro Arnt Sant'Ana   +9 more
wiley   +1 more source

Investigation of Plant Growth Promotion Potential of Novel Compost‐Derived Bacilli and Anticipating Their In Vivo Effectiveness Through Mathematical Modelling

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Compost derived Bacillus isolates were screened for plant growth promoting traits, scored through modelling and validated in field trials on maize and okra. Selected strains enhanced growth significantly, enabling reduced chemical fertiliser use, ecofriendly bioinputs and improved soil health.
Debapriya Maitra   +9 more
wiley   +1 more source

The Oldest Traces of Alcoholic Beverages in the Border Zone of the North and East European Plains

open access: yesArchaeometry, Volume 68, Issue 2, Page 153-172, April 2026.
ABSTRACT Analysis of organic compounds preserved on pottery from the Bell Beaker community and the initial phase of the Trzciniec Cultural Sphere in the border zone of the Eastern and North European Plains was prompted by traces of alcoholic beverages found in contextually and formally analogous discoveries of more westerly provenance.
Dariusz Manasterski   +4 more
wiley   +1 more source

Use of the oral microbiota as screening test to identify children at risk for caries development. A systematic review of longitudinal studies

open access: yesEuropean Journal of Oral Sciences, Volume 134, Issue 2, April 2026.
Abstract This study investigated trends in oral microbiota composition (index test) that could indicate potential candidates to identify children at risk for dental caries development compared with visual/tactile examination (reference test). MEDLINE/PubMed, Web of Science, Embase, Scopus, Lilacs, SciELO, and Google Scholar databases were searched up ...
Heitor Sales de Barros Santos   +3 more
wiley   +1 more source

Loss of Kv8.2 in the Mouse Retina Is Associated With Altered One‐Carbon Metabolism

open access: yesJournal of Neurochemistry, Volume 170, Issue 4, April 2026.
Kv8.2 knockout mice, a model of KCNV2 retinopathy, exhibit impaired potassium homeostasis in photoreceptors and slowly progressive rod degeneration. To investigate metabolic adaptations accompanying this dysfunction, untargeted metabolomic profiling was performed on mouse retinas.
Karina Kruth, Sheila A. Baker
wiley   +1 more source

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