Results 171 to 180 of about 7,622 (205)

Sirtuin 5-mediated desuccinylation of Slc25a4 inhibits osteoporosis by enhancing mitochondrial respiration. [PDF]

Bone Res
Chen J, Jiang X.
europepmc   +1 more source

The tumor microenvironment shapes gastric cancer progression by coordinating immune suppression and metabolic reprogramming. [PDF]

Front Immunol
Jiao F, Wang Z, Yuan J, Shi F, Zhang S.
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The methylation site cg06972019 regulates the succinylation-related gene ENO1 to inhibit the occurrence of erectile dysfunction. [PDF]

Hereditas
Wang J, Ye S, Xu M, Sun M, Lu Y, Piao Z, Teng F, Zhang M.   +7 more
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Post-translational modifications at the crossroads of cancer metabolism and immune regulation: therapeutic opportunities and challenges. [PDF]

Int J Surg
Liu J, Sun J, Li C, Shan X, Yue F, Wu G, Wu G.   +6 more
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Curcumin inhibits ferroptosis through dessuccinylation of SIRT5-associated ACSL4 protein, and plays a chondroprotective role in osteoarthritis. [PDF]

PLoS One
Xu Y, Li Y, Liu L, Jing Q, Ye X.
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Editorial: Hepatocellular carcinoma: novel treatment strategies, volume III. [PDF]

Front Med (Lausanne)
Feng F, Xu X.
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Succinylation of tumor suppressor PPP2R1A K541 by HAT1 converses the role in modulation of gluconeogenesis/lipogenesis remodeling to display oncogene function. [PDF]

Acta Pharm Sin B
Yang G, Wang Y, Yuan H, Zhang H, Zhao L, Hou C, Lv P, Hao J, Zhang X.   +8 more
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P23 acts as a negative regulator of ferroptosis in NSCLC by blocking GPX4 degradation via chaperone-mediated autophagy. [PDF]

Mol Cancer
Chen J, Peng Y, Zhou M, Che Y, Zhao S, He C, Zhang W, Tian X, Zhang W, Liu Z, Zhou M, Liang G, Huo X, Wang Y, Yu Z, Ma X.   +15 more
europepmc   +1 more source

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Succinylation of myosin

Archives of Biochemistry and Biophysics, 1967
Abstract The reaction of succinic anhydride with the free amino groups of myosin introduced a high negative charge density and thus greatly altered the properties of this protein. Succinylated myosin was water-soluble and remained so even after prolonged heating.
H, Oppenheimer, K, Bárány, G, Hamoir, J, Fenton   +3 more
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Succinylation of Gamma Globulin

Nature, 1966
THE chemical modification of proteins with succinic anhydride was shown by Habeeb et al.1 to result in an unfolding of the compact conformations of several proteins in neutral aqueous buffer. This was attributed to the large increase in net negative charge produced by the replacement of the positively charged e-NH3+ groups of lysine residues by ...
J, Lenard, S J, Singer
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