Lysine succinylation, the metabolic bridge between cancer and immunity [PDF]
Genes and Diseases, 2023 Lysine succinylation is a naturally occurring post-translational modification (PTM) that regulates the stability and function of proteins. It can be regulated by enzymes such as SIRT5 and SIRT7.
Shuye Lin, Teng Ma, Hongyun Ruan
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Enzymatic and metabolic regulation of lysine succinylation [PDF]
Genes and Diseases, 2020 Lysine succinylation (Ksucc), defined as a transfer of a succinyl group to a lysine residue of a protein, is a newly identified protein post-translational modification1–3.
Taro Hitosugi
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Large-Scale Assessment of Bioinformatics Tools for Lysine Succinylation Sites [PDF]
Cells, 2019 Lysine succinylation is a form of posttranslational modification of the proteins that play an essential functional role in every aspect of cell metabolism in both prokaryotes and eukaryotes.
Mst Shamima Khatun +2 more
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First comprehensive analysis of lysine succinylation in paper mulberry (Broussonetia papyrifera) [PDF]
BMC Genomics, 2021 Background Lysine succinylation is a naturally occurring post-translational modification (PTM) that is ubiquitous in organisms. Lysine succinylation plays important roles in regulating protein structure and function as well as cellular metabolism. Global
Yibo Dong, Ping Li, Ping Li, Chao Chen
doaj +2 more sources
Proteome-Wide Identification of Lysine Succinylation in the Proteins of Tomato (Solanum lycopersicum) [PDF]
PLoS ONE, 2016 Post-translational modification of proteins through lysine succinylation plays important regulatory roles in living cells. Lysine succinylation was recently identified as a novel post-translational modification in Escherichia coli, yeast, Toxoplasma ...
Weibo Jin, Fangli Wu
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First Succinylome Profiling of Vibrio alginolyticus Reveals Key Role of Lysine Succinylation in Cellular Metabolism and Virulence [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Recent studies have shown that a key strategy of many pathogens is to use post-translational modification (PTMs) to modulate host factors critical for infection.
Fuyuan Zeng +19 more
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Comprehensive Succinylome Profiling Reveals the Pivotal Role of Lysine Succinylation in Energy Metabolism and Quorum Sensing of Staphylococcus epidermidis [PDF]
Frontiers in Microbiology, 2021 BackgroundLysine succinylation is a newly identified posttranslational modification (PTM), which exists widely from prokaryotes to eukaryotes and participates in various cellular processes, especially in the metabolic processes.
Yiping Zhao +9 more
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Deep_KsuccSite: A novel deep learning method for the identification of lysine succinylation sites [PDF]
Frontiers in Genetics, 2022 Identification of lysine (symbol Lys or K) succinylation (Ksucc) sites centralizes the basis for disclosing the mechanism and function of lysine succinylation modifications.
Xin Liu +6 more
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Global analysis of protein lysine succinylation profiles in common wheat [PDF]
BMC Genomics, 2017 Background Protein lysine succinylation is an important post-translational modification and plays a critical regulatory role in almost every aspects of cell metabolism in both eukaryotes and prokaryotes.
Yumei Zhang +6 more
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Lysine succinylation as a metabolic switch in cardiovascular diseases: Mechanistic insights and therapeutic perspectives [PDF]
Redox BiologyCardiovascular diseases (CVDs) are life-threatening disorders arising from interactions between genetic and environmental factors, imposing a heavy global health burden with high morbidity and mortality.
Fei Mu +9 more
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