Quantitative proteome and lysine succinylome characterization of zinc chloride smoke-induced lung injury in mice [PDF]
HeliyonThe inhalation of zinc chloride (ZnCl2) smoke is one of common resources of lung injury, potentially resulting in severe pulmonary complications and even mortality.
Xie Fei, Wanmei Wang
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Acetylome and Succinylome Profiling of Edwardsiella tarda Reveals Key Roles of Both Lysine Acylations in Bacterial Antibiotic Resistance [PDF]
Antibiotics, 2022 The antibiotic resistance of Edwardsiella tarda is becoming increasingly prevalent, and thus novel antimicrobial strategies are being sought. Lysine acylation has been demonstrated to play an important role in bacterial physiological functions, while its
Yuying Fu +7 more
doaj +2 more sources
Identification of Lysine Succinylome and Acetylome in the Vancomycin-Intermediate Staphylococcus aureus XN108 [PDF]
Microbiology Spectrum, 2022 Protein posttranslational modifications (PTMs) play important roles in regulating numerous biological functions of prokaryotic and eukaryotic organisms.
Li Tan +7 more
doaj +2 more sources
Global proteome analyses of phosphorylation and succinylation of barley root proteins in response to phosphate starvation and recovery [PDF]
Frontiers in Plant Science, 2022 Phosphate (Pi) stress is an important environmental factor that limits plant growth and development. Of various posttranslational modifications (PTMs), protein phosphorylation and succinylation are the two most important PTMs that regulate multiple ...
Juncheng Wang +20 more
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Comprehensive analysis of the succinylome in Vero cells infected with peste des petits ruminants virus Nigeria 75/1 vaccine strain [PDF]
BMC Veterinary ResearchBackground Peste des petits ruminants virus (PPRV) is currently the only member of the Morbillivirus caprinae species within the genus Morbillivirus of the family Paramyoxviridae.
Xuelian Meng +5 more
doaj +2 more sources
Elevated BACH1 Contributes to Mitochondrial Succinylome Remodeling and Trophoblast Bioenergetic Dysfunction in Preeclampsia [PDF]
AntioxidantsPreeclampsia (PE) is a major pregnancy complication characterized by placental dysfunction and metabolic disturbances. Although mitochondrial abnormalities are frequently observed in PE, the upstream regulatory mechanisms remain incompletely understood ...
Jiacheng Xu +12 more
doaj +2 more sources
Comprehensive analysis of the lysine succinylome in fish oil-treated prostate cancer cells [PDF]
Life Science Alliance, 2023 Through a global lysine succinylation analysis of prostate cancer cells treated with fish oil, a significant number of lysine succinylation sites have been identified and FO-dependent GOT2 succinylation status may have a potential to inhibit building ...
Yifan Jiang +8 more
doaj +2 more sources
Dynamic lysine acetylation and succinylation of platelet proteins regulates platelet storage lesion: mechanistic insights from multi-omics [PDF]
Annals of MedicineObjectives Platelet storage lesion (PSL) severely impairs platelet function during storage, presenting a major hurdle in transfusion medicine; however, the dynamic interplay between global proteomic changes and post-translational modifications (PTMs ...
Xin Liao +8 more
doaj +2 more sources
Adipose tissue protein profiling: modulation by vitamin D receptor [PDF]
Frontiers in NutritionBackgroundLittle is known regarding the expression patterns of adipose tissue proteins in the context of vitamin D deficiency and whether these expression patterns have adverse effects on fat-related diseases.MethodsThis study compares vitamin D receptor-
Ding Ding +7 more
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Journal of Advanced Research, 2021 Introduction: Major depressive disorder is caused by gene–environment interactions, and the host microbiome has been recognized as an important environmental factor.
Hong Wei, Peng Xie, Lanxiang Liu
exaly +3 more sources