Results 121 to 130 of about 423 (139)
Quantitative succinylome analysis in the liver of non-alcoholic fatty liver disease rat model [PDF]
Non-alcoholic fatty liver disease (NAFLD) is a clinical frequent disease. However, its pathogenesis still needs further study, especially the mechanism at the molecular level. The recent identified novel protein post-translational modification, lysine succinylation was reported involved in diverse metabolism and cellular processes.
Jianjie Chen, Jian Ping
exaly +5 more sources
Lysine succinylation has been recognized as a post-translational modification (PTM) in recent years. It is plausible that succinylation may have a vaster functional impact than acetylation because of bulkier structural changes and more significant charge differences on the modified lysine residue.
Zhaohua Peng, Xiaoxi Meng, Cailin Wang
exaly +3 more sources
Abstract As a novel protein post-translational modification, lysine succinylation is widely involved in metabolism regulation. To describe succinylated lysine's physiological functions and distribution patterns in Saccharopolyspora erythraea, a large and global protein succinylome was identified in a hypersuccinylated strain E3ΔsucC, using high-
Ju Chu, Ju Chu, Muhammad Hammad Hussain
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Global landscape of lysine succinylome in Saccharopolyspora erythraea
2023As a novel protein post-translational modification, lysine succinylation is widely involved in metabolism regulation. In this study, we focused on the distribution of lysine succinylation sites and their physiological functions in Saccharopolyspora erythraea.
Xiang Ke, xing jiang, Xiwei Tian, ju chu
openaire +1 more source
Fish & Shellfish Immunology, 2022
Lysine succinylation is a novel protein post-translational modification associated with the regulation of a variety of cellular processes. Post-translational modifications may regulate the immune response of Pinctada fucata martensii, a marine bivalve used to produce cultured pearls, in response to the surgical implantation of the seed pearl.
Meizhen Zhang +5 more
openaire +2 more sources
Lysine succinylation is a novel protein post-translational modification associated with the regulation of a variety of cellular processes. Post-translational modifications may regulate the immune response of Pinctada fucata martensii, a marine bivalve used to produce cultured pearls, in response to the surgical implantation of the seed pearl.
Meizhen Zhang +5 more
openaire +2 more sources
Systematic Proteome and Lysine Succinylome Analysis Reveals Enhanced Cell Migration by Hyposuccinylation in Esophageal Squamous Cell Carcinoma [PDF]
Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with poor therapeutic outcomes. However, the alterations in proteins and posttranslational modifications (PTMs) leading to the pathogenesis of ESCC remain unclear. Here, we provide the comprehensive characterization of the proteome, phosphorylome, lysine acetylome, and succinylome ...
Kai Zhang, Guijin Zhai, Zhiyong Wu
exaly +3 more sources
Systematic Analysis of the Lysine Succinylome in Candida albicans
Journal of Proteome Research, 2016Candida albicans is the most common human fungal pathogen for both immunocompetent and immunocompromised individuals. Lysine succinylation is a frequently occurring post-translational modification that is found in many organisms; however, the role of succinylation is still under investigation.
Hailin, Zheng +9 more
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Proteomics, 2018
AbstractIn light of the increasing incidence of renal cell carcinoma (RCC), its molecular mechanisms have been comprehensively explored in numerous recent studies. However, few studies focus on the influence of multi‐factor interactions during the occurrence and development of RCC. This study aims to investigate the quantitative global proteome and the
Yuyan Zhu, Xiankui Liu, Zeliang Li
exaly +3 more sources
AbstractIn light of the increasing incidence of renal cell carcinoma (RCC), its molecular mechanisms have been comprehensively explored in numerous recent studies. However, few studies focus on the influence of multi‐factor interactions during the occurrence and development of RCC. This study aims to investigate the quantitative global proteome and the
Yuyan Zhu, Xiankui Liu, Zeliang Li
exaly +3 more sources
Global analysis of lysine succinylome in the periodontal pathogen Porphyromonas gingivalis
Molecular Oral Microbiology, 2019AbstractThe gram‐negative anaerobe Porphyromonas gingivalis is not only a keystone periodontal pathogen but also an emerging systemic pathogen. Although the newly discovered protein post‐translational modification (PTM), lysine succinylation (Ksuc), appears to play an important role in modulating metabolic processes in bacteria, this PTM has not been ...
Leng Wu +6 more
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Breast Cancer, 2018
Breast cancer, the most common invasive cancer and cause of cancer-related death in women worldwide, is a multifactorial, complex disease, and many molecular players and mechanisms underlying the complexity of its clinical behavior remain unknown.To explore the molecular features of breast cancer, quantitative proteome and succinylome analyses in ...
Chenchen, Liu +6 more
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Breast cancer, the most common invasive cancer and cause of cancer-related death in women worldwide, is a multifactorial, complex disease, and many molecular players and mechanisms underlying the complexity of its clinical behavior remain unknown.To explore the molecular features of breast cancer, quantitative proteome and succinylome analyses in ...
Chenchen, Liu +6 more
openaire +2 more sources

