Results 211 to 220 of about 1,032,066 (371)

OPTIMIZATION OF MEDIUM COMPOSITIONS FOR SACCHAROMYCES BOULARDII BY BOX-BEHNKEN DESIGN

open access: yesScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2016
Based on the previous experimental results, the Box-Behnken design (BBD) was employed to study the individual and interactive effects of sucrose, malt extract, calf serum and sodium citrate on the growth of Saccharomyces boulardii, and the optimum medium
ZHANGTENG LEI   +4 more
doaj  

Screening and Identification of Novel DNA Aptamer for Targeted Delivery to Injured Podocytes in Glomerular Diseases

open access: yesAdvanced Science, EarlyView.
This study develops RLS‐2, a high‐affinity aptamer that specifically targets injured podocytes, making it a promising candidate for targeted drug delivery. In vitro, RLS‐2 shows stability, specificity, efficient siRNA delivery via AsiCs, and uptake by podocytes.
Chao Zhou   +9 more
wiley   +1 more source

MEA‐seqX: High‐Resolution Profiling of Large‐Scale Electrophysiological and Transcriptional Network Dynamics

open access: yesAdvanced Science, EarlyView.
How can we fully understand brain function and disease without uncovering the causal coordination between molecular and neural activity across space and time? MEA‐seqX tackles this challenge by integrating advanced electrophysiology, spatial transcriptomics, and artificial intelligence predictions, revealing multiscale dynamics.
Brett Addison Emery   +9 more
wiley   +1 more source

Role of Testosterone Signaling in Microglia: A Potential Role for Sex‐Related Differences in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Testosterone enhances Aβ‐induced autophagy in microglia via the non‐genomic testosterone receptor GPRC6A, promoting Aβ clearance by suppressing ERK phosphorylation and inhibiting mTOR activation. In male 5xFAD mice, testicular removal reduces microglial autophagy and Aβ clearance, which is restored by testosterone.
Haiyan Du   +8 more
wiley   +1 more source

A Cascade of Sequentially Expressed Sucrose Transporters in the Seed Coat and Endosperm Provides Nutrition for the Arabidopsis Embryo[OPEN]

open access: yesThe Plant Cell, 2015
Li‐Qing Chen   +7 more
semanticscholar   +1 more source

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