Results 71 to 80 of about 24,449 (255)

Prescribed pharmaceutical alternatives initiative coinciding with reductions in unregulated street opioid use among young people who use drugs: An interrupted time series analysis

open access: yesAddiction, EarlyView.
Abstract Background and aims In British Columbia, Canada, an initiative was implemented in 2020 to reduce overdose mortality by prescribing pharmaceutical opioids (primarily hydromorphone) as a substitute for the toxic unregulated drug supply. This study estimated changes in the level and trend of unregulated opioid use and non‐prescribed hydromorphone
Erica McAdam   +7 more
wiley   +1 more source

Sufentanil for chronic pain management

open access: yes, 2010
Sufentanil is a highly potent synthetic opioid that is approximately 1000-fold more potent than morphine and up to tenfold more potent than fentanyl. It is most commonly used by anesthesiologists to provide intraoperative analgesia.
Girish P Joshi
core   +1 more source

Remapping the Synthetic Landscape of α‐Tertiary Alkylamines via Dual‐Functional Catechol

open access: yesAngewandte Chemie, Volume 138, Issue 37, 7 September 2026.
A three‐component assembly strategy has been developed for the modular synthesis of hindered α‐tertiary aliphatic amines from readily available precursors through unlocking the dual role of catechol. The practicality of this methodology has been demonstrated in over 90 examples, including compounds that are otherwise difficult to access, along with ...
Chen‐Yan Cai, Yuzuru Kanda, Tian Qin
wiley   +2 more sources

A Response Surface Analysis of the Combination of Dexmedetomidine and Sufentanil for Attenuating the Haemodynamic Response to Endotracheal Intubation

open access: yesDose-Response, 2022
Purpose Dexmedetomidine combined with opioids has been extensively used to blunt cardiovascular responses to endotracheal intubation. To determine their interaction, we aimed to develop a response surface model between dexmedetomidine and sufentanil ...
Peng Su   +7 more
doaj   +1 more source

Combination of sufentanil, dexmedetomidine and ropivacaine to improve epidural labor analgesia effect: A randomized controlled trial

open access: yesExperimental and Therapeutic Medicine, 2020
Opioids and α2-agonists have been used as epidural adjuvants in local anesthetics for a long time, but the effect of the combination of opioids and α2-agonists as epidural adjuvants is not completely understood.
Gehui Li   +7 more
semanticscholar   +1 more source

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

open access: yesAllergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud   +14 more
wiley   +1 more source

Electrochemical Biosensor for the Determination of Sufentanil in Human Plasma and Urine based on TiO2 -Graphene Composite modified carbon paste electrode

open access: yesInternational Journal of Electrochemical Science, 2021
In this work, the synthesis of TiO2 and graphene nanocomposite modified carbon paste electrode (TiO2-GO/CPE) as an electrochemical biosensor for the detection of sufentanil in human plasma and urine was investigated.
Hongchao Zhang, Youli He
doaj   +1 more source

Comparison of Sufentanil- and Fentanyl-based Intravenous Patient-controlled Analgesia on Postoperative Nausea and Vomiting after Laparoscopic Nephrectomy: A Prospective, Double-blind, Randomized-controlled Trial

open access: yesInternational Journal of Medical Sciences, 2020
Background: The incidence of postoperative nausea and vomiting (PONV) remains high. The effects of sufentanil for PONV is not firmly confirmed. The aim of this study was to compare the effect of sufentanil- and fentanyl-based intravenous patient ...
H. Lee   +4 more
semanticscholar   +1 more source

Planned cesarean section or attempted vaginal delivery: Which is more environmentally friendly? An observational life cycle assessment study in France

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
In this life cycle assessment study conducted in a French hospital, attempted vaginal delivery showed substantially lower environmental impacts than planned cesarean section, including reduced greenhouse gas emissions, resource use, and water consumption, highlighting its greater environmental sustainability in childbirth care.
Sherazade Jaafar   +3 more
wiley   +1 more source

Impact of Respiratory Support Strategies on CO2 Variability During Therapeutic Hypothermia in Neonates With Asphyxia: Data From the German Hypothermia Registry

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To evaluate associations between respiratory support strategies, partial pressure of carbon dioxide (pCO2) variability and oxygen exposure in neonates with hypoxic–ischaemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). Methods This retrospective multicentre study used data from the German Hypothermia Registry, including ...
Sebiha Demir   +93 more
wiley   +1 more source

Home - About - Disclaimer - Privacy