Results 81 to 90 of about 24,449 (255)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Comparison of clinical effects according to the dosage of sufentanil added to 0.5% hyperbaric bupivacaine for spinal anesthesia in patients undergoing cesarean section [PDF]

Korean Journal of Anesthesiology, 2012
BackgroundSubarachnoid block is a widely used technique for cesarean section. To improve the quality of analgesia and prolong the duration of analgesia, addition of intrathecal opioids to local anesthetics has been encouraged.
Yun Sic Bang, Kum-Hee Chung, Jung Hyang Lee, Seung-Ki Hong, Seok Hwan Choi, Jong-Yeon Lee, Su-Yeon Lee, Hyeon Jeong Yang   +7 more
doaj   +1 more source

Economic evaluations of remifentanil versus fentanyl for analgo‐sedation in mechanically ventilated adult ICU patients: a systematic review

Internal Medicine Journal, EarlyView.
Abstract The use of opioid and sedative infusions to relieve pain and anxiety is common among patients receiving invasive mechanical ventilation (IMV) in the intensive care unit (ICU). Although remifentanil‐based sedation is feasible, evidence regarding its economic impact remains limited.
Sushma Ashwin, Lisa Gold, Arvind Rajamani, Ashwin Subramaniam   +3 more
wiley   +1 more source

Comparison of extradural administration of sufentanil, morphine and sufentanil-morphine combination after caesarean section.

, 1992
We have studied postoperative analgesia and unwanted side effects of a single dose of a mixture of morphine and sufentanil administered extradurally with the effects produced by extradural injection of each opioid alone in 64 patients after Caesarean ...
Morel DR, Dottrens M, Rifat K
core   +1 more source

Analgesic Effect Comparison Between Nalbuphine and Sufentanil for Patient-Controlled Intravenous Analgesia After Cesarean Section

Frontiers in Pharmacology, 2020
Background: Efficient maternal pain relief after cesarean delivery remains challenging, but it is important to improve outcomes for the mother and the newborn during the puerperium.
Shen Sun, Yun-Dong Guo, Ting-Ting Wang, Shao-Qiang Huang   +3 more
semanticscholar   +1 more source

The ultrarapid delayed rectifier potassium current has important functional role in the repolarization reserve of canine and human ventricular muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular ...
Alaa Amin E. Abdelmagid, Aiman Saleh A. Mohammed, Gábor Mohácsi, Benjámin Paskuj, Gergő Bitay, Jakub Tomek, Sahil Dalal, Tamás Árpádffy‐Lovas, Vivien Demeter‐Haludka, István Koncz, Muhammad Naveed, László Virág, Norbert Nagy, András Varró, István Baczkó, Norbert Jost, Zsófia Kohajda, Leila Topal   +17 more
wiley   +1 more source

Analgesic Effects of Intrathecal Sufentanil Added to Lidocaine 5% in Elective Cesarean Section [PDF]

Acta Medica Iranica, 2010
The quality of subarachnoid block can be improved by adding opioids to the local anesthetics. We compared the analgesic effects of different doses of intrathecal sufentanil added to lidocaine %5 for elective cesarean section. This study was a prospective,
Mohammad Hosein Bakhshaei, Nahid Manuchehrian, Ebrahim Khoshraftar, Hassan Mohamadipour-Anvary, Mehdy Sanatkarfar   +4 more
doaj   +1 more source

Comparison of Intrathecal Injection of Fentanyl and Sufentanil on the Onset, Duration, and Quality of Analgesia in Labor: A Randomized, Double-Blind Clinical Trial

Anesthesiology and Pain Medicine, 2020
Background Labor pain is a severe pain, and intrathecal opioid injection is one of the analgesia methods to reduce it. Objectives We assessed the effects of intrathecal Fentanyl and Sufentanil on the onset, duration, and quality of analgesia for labor ...
N. Manouchehrian, S. Rabiei, A. Moradi, Zahra Lakpur   +3 more
semanticscholar   +1 more source

Virtual Reality for Anxiety and Pain Management in Lower Limb Orthopedic Surgery Under Spinal Anesthesia: A Randomized Controlled Trial

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Patients undergoing lower limb orthopedic surgery under spinal anesthesia often experience significant perioperative anxiety and discomfort. Virtual reality (VR) has emerged as a promising non‐pharmacological intervention for anxiety and pain management.
Fedi Ben Dhaou, Yosra Mejdoub, Maroua Trigui, Emna Mziou, Amal Ayedi, Meriam Boussarsar, Mariem Keskes, Yassine Maktouf, Fares Mezghani, Mohamed Seddik Regaieg, Tarek Bardaa, Chams Elhouda Ben Dhaou, Hichem Cheikhrouhou, Imen Zouche   +13 more
wiley   +1 more source

Comparison of ED95 of Butorphanol and Sufentanil for gastrointestinal endoscopy sedation: a randomized controlled trial

BMC Anesthesiology, 2020
Background Butorphanol, a synthetic opioid partial agonist analgesic, has been widely used to control perioperative pain. However, the ideal dose and availability of butorphanol for gastrointestinal (GI) endoscopy are not well known.
Xiao-Na Zhu, Limei Chen, Shuang-Li Zheng, L. Pan   +3 more
semanticscholar   +1 more source