Results 81 to 90 of about 893,890 (356)

Perspective: Total, Added, or Free? What Kind of Sugars Should We Be Talking About?

Advances in Nutrition, 2018
There is consistent public guidance to limit sugars intakes. However, WHO recommendations are for “free” sugars, whereas some other guidance documents and public discussion focus on “added” sugars, and globally most food labeling states “total” sugars ...
D. Mela, Elizabeth M. Woolner
semanticscholar   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Heterogeneously Catalyzed Hydrothermal Processing of C5-C6 Sugars.

Chemical Reviews, 2016
Biomass has been long exploited as an anthropogenic energy source; however, the 21st century challenges of energy security and climate change are driving resurgence in its utilization both as a renewable alternative to fossil fuels and as a sustainable ...
Xingguang Zhang, K. Wilson, A. Lee
semanticscholar   +1 more source

Total free sugars, reducing sugars and glucose [PDF]

, 1981
Carbohydrates in the tissues of crustaceans exist as free sugars and as bound with proteins (Saravanan, 1979). The free sugars in haemolymph consist of mono, di and oligosaccharides.
Ravindranath, M H, Saravanan, T S
core  

Changes in free amino acids and sugars in potatoes due to sulfate fertilization and the effect on acrylamide formation

, 2007
To examine how sulfur deprivation may affect acrylamide formation in cooked potatoes, three varieties of potato were grown under conditions of either severe sulfur deprivation or an adequate supply of sulfur. In all three varieties sulfur deprivation led
Halford, Nigel G., Mottram, D.S., Muttucumaru, N., Muttucumaru, Nira, Parry, M. A. J., Elmore, J. S., Mottram, D. S., Halford, N. G., Elmore, J. Stephen, Mottram, Donald S., Dodson, A. T., Parry, M.A.J., Elmore, J.S., Dodson, Andrew T., Parry, M. A J, Halford, N.G., Dodson, A.T., Muttucumaru, N.   +17 more
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Amish Economic Transformations: New Forms of Income and Wealth Distribution in a Traditionally “Flat” Community

The Journal of Amish and Plain Anabaptist Studies, 2014
The basic contours of the Amish economic transformation over the past few decades have been well documented, including the demographic squeeze that pushed many Amish out of farming, their embrace of cottage industries and, to a lesser extent, factory ...
Amyaz Moledina, David McConnell, Stephanie Sugars, Bailey Conner   +3 more
doaj  

Effect of the Flash Vacuum Expansion (FVE) Process on the Response of Limosilactobacillus fermentum J24 to the Metabolism of Sugars and Organic Acids During the Development of a Papaya-Based Drink

Beverages
The flash vacuum expansion (FVE) process is an unconventional technology that enables the generation of fruit purees by altering the state of the water stored in the vacuoles. The plant tissue is subjected to an increase in temperature (from 25 to 54 °C)
María de Jesús Torres-Llanez, José Isidro Méndez-Romero, Jesús Ayala-Zavala, Aarón Fernando González-Córdova, Belinda Vallejo-Cordoba, Marco Antonio Salgado-Cervantes, Manuel Vargas-Ortiz, Teresita de Jesús Castillo-Romero   +7 more
doaj   +1 more source

A Higher Abundance of O-Linked Glycans Confers a Selective Advantage to High Fertile Buffalo Spermatozoa for Immune-Evasion From Neutrophils

Frontiers in Immunology, 2020
The glycans on the plasma membrane of cells manifest as the glycocalyx, which serves as an information-rich frontier that is directly in contact with its immediate milieu. The glycoconjugates (GCs) that adorn most of the mammalian cells are also abundant
Vipul Batra, Komal Dagar, Samiksha Nayak, Arumugam Kumaresan, Rakesh Kumar, Tirtha K. Datta   +5 more
doaj   +1 more source