Results 51 to 60 of about 29,384 (211)

A real‐world study on different initiation times and treatment durations of letermovir for cytomegalovirus prophylaxis after allogeneic haematopoietic stem cell transplantation

British Journal of Haematology, EarlyView.
Early letermovir initiation (day 0) after allogeneic haematopoietic stem cell transplantation (allo‐HSCT) reduced early cytomegalovirus (CMV) infection and delayed first CMV DNAemia compared with later starts. Extending prophylaxis to 200 days virtually eliminated late CMV reactivation and improved 1‐year overall survival, with no grade ≥3 drug‐related
Shiyu Chen, Zhihang Su, Xiaohan Zhang, Xiaoqing Li, Xin Du   +4 more
wiley   +1 more source

Penicillin kills chlamydia following the fusion of bacteria with Lysosomes and prevents genital inflammatory lesions in C. muridarum-infected mice [PDF]

, 2013
The obligate intracellular bacterium Chlamydia exists as two distinct forms. Elementary bodies (EBs) are infectious and extra-cellular, whereas reticulate bodies (RBs) replicate within a specialized intracellular compartment termed an ‘inclusion ...
Le Gall, SM, Colette Kanellopoulos-Langevin, Le Gall Sylvain M., Habbeddine, M, Sylvain M. Le Gall (108751), Habbeddine, Mohamed, Delarbre, C., Dumoux, M, Maud Dumoux (501153), Dumoux, Maud, Delarbre, C, Dumoux Maud, Christiane Delarbre, Hayward Richard D., Philippe Verbeke, Delarbre Christiane, Verbeke, Philippe, Kanellopoulos-Langevin Colette, Kanellopoulos-Langevin, C, Le Gall, Sylvain M, Habbeddine Mohamed, Philippe Verbeke (16975), Hayward, RD, Hayward, Richard D, Richard D Hayward, Christiane Delarbre (501155), Delarbre, Christiane, Le Gall, S.M., Habbeddine, M., Kanellopoulos-Langevin, C., Hayward, Richard D., Colette Kanellopoulos-Langevin (146985), Mohamed Habbeddine (501154), Ramsey, K., Richard D. Hayward (272234), Verbeke, P., Verbeke, P, Kanellopoulos-Langevin, Colette, Sylvain M Le Gall, Maud Dumoux, Mohamed Habbeddine, Verbeke Philippe   +41 more
core   +1 more source

Targeting Multidrug-Resistant Acinetobacter spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent

mBio, 2019
Multidrug-resistant (MDR) Acinetobacter spp. poses a significant therapeutic challenge in part due to the presence of chromosomally encoded β-lactamases, including class C Acinetobacter-derived cephalosporinases (ADC) and class D oxacillinases (OXA), as ...
Melissa D. Barnes, Vijay Kumar, Christopher R. Bethel, Samir H. Moussa, John O’Donnell, Joseph D. Rutter, Caryn E. Good, Kristine M. Hujer, Andrea M. Hujer, Steve H. Marshall, Barry N. Kreiswirth, Sandra S. Richter, Philip N. Rather, Michael R. Jacobs, Krisztina M. Papp-Wallace, Focco van den Akker, Robert A. Bonomo   +16 more
doaj   +1 more source

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source

Perioperative antibiotic prophylaxis in surgery

Perioperative Medicine, 2021
Infectious complications in surgery occupy a significant place among the causes of death and increase in the cost of medical care for various pathologies.
Dmytro Dmytriiev, Oleksandr Nazarchuk, Yuliana Babina   +2 more
doaj   +1 more source

The role of antibiotics in preventing surgical complications in periodontology and implant dentistry

Periodontology 2000, EarlyView.
Abstract Antibiotics are commonly prescribed in periodontal and implant surgeries, either before, during or after surgery, to prevent postoperative infection and reduce early implant failure. However, the potential benefits may be undermined by the risks of resistance and sensitization, thus requiring a strict indication for prescription.
Zhaozhao Chen, Lan‐Lin Chiou, Javier Calatrava, Hom‐Lay Wang   +3 more
wiley   +1 more source

Perioperative Prophylaxis in Pediatric Solid Organ Transplantation: A Baseline Stewardship Audit Using Routine Electronic Data

Transplant Infectious Disease, EarlyView.
Using routine electronic data from 164 pediatric transplants, we created reproducible stewardship measures of perioperative prophylaxis practice across transplant populations and protocol pathways. Starting prophylaxis was reliable, but continuation beyond intended stop targets—especially in abdominal transplantation—identified the clearest target for ...
Charles B. Foster, Kaitlyn Rivard, Venkatraman A. Arakoni, Blanca E. Gonzalez   +3 more
wiley   +1 more source

Comparison of Tigecycline or Cefoperazone/Sulbactam therapy for bloodstream infection due to Carbapenem-resistant Acinetobacter baumannii

Antimicrobial Resistance and Infection Control, 2019
Background We retrospectively analyzed the effect of tigecycline and cefoperazone/sulbactam therapies on the prognosis of patients with carbapenem-resistant Acinetobacter baumannii bloodstream infection (CRAB-BSI).
Tianshui Niu, Qixia Luo, Yaqing Li, Yanzi Zhou, Wei Yu, Yonghong Xiao   +5 more
doaj   +1 more source

Sulbactam pivoxil powder attributes and compatibility study with excipients [PDF]

, 2021
Background: Sulbactam pivoxil is an irreversible β-lactamase inhibitor that can be used with β-lactam antibiotics to improve antibacterial therapy by the oral route.
Ramírez Rigo, María Veronica, González Vidal, Noelia Luján, Ferreira, Fabio F., Gallo, Loreana Carolina   +3 more
core   +1 more source

Infection with the Neorickettsial Organism Stellantchasmus falcatus Agent in an Arctic Fox (Vulpes lagopus)

Veterinary Clinical Pathology, EarlyView.
ABSTRACT A 1‐year‐old female‐intact arctic fox (Vulpes lagopus) presented for diarrhea, lethargy, severe thrombocytopenia, and hyperbilirubinemia. Blood film evaluation revealed intracytoplasmic coccoid bacteria within moderate numbers of leukocytes consistent with infection by a rickettsial organism.
Jeremy P. Bessett, Alexis G. Davidson, Alyssa M. Scagnelli, Kristen R. Friedrichs   +3 more
wiley   +1 more source