Results 51 to 60 of about 20,006 (291)

Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies [PDF]

, 2009
BACKGROUND: Very few data on anti-malarial efficacy are available from the Democratic Republic of Congo (DRC). DRC changed its anti-malarial treatment policy to amodiaquine (AQ) and artesunate (AS) in 2005.
A Brockman, A Nahum, A Ndayiragije, AM Kabanywanyi, AO Talisuna, AP Alker, B Greenhouse, Chantal van Overmeir, CV Plowe, Célestin Nsibu Ndosimao, D Francis, Elizabeth Ashley, G Snounou, Ingrid van den Broek, Jean-Paul Guthmann, Jean-Paul Guthmann, JG Kublin, JG Kublin, JP Guthmann, Juliet Kyomuhendo, LC Ranford-Cartwright, M Ndounga, M Ndounga, Maryline Bonnet, Michel van Herp, MR Kamya, P Piola, Pedro Pablo Palma Urrutia, R Pearce, RN Price, S Cohuet, TB Swarthout, World Health Organization   +32 more
core   +2 more sources

Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso

Malaria Journal, 2004
The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported.
Traore Corneille, Müller Olaf, Kouyate Bocar   +2 more
doaj   +1 more source

Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children. [PDF]

, 2008
BACKGROUND: Use of different methods for assessing the efficacy of artemisinin-based combination antimalarial treatments (ACTs) will result in different estimates being reported, with implications for changes in treatment policy.
A Yeka, B Greenhouse, CH Sibley, E Depoortere, Eleanor Turyakira, Elizabeth A Ashley, F Grandesso, Francesco Checchi, Grant Dorsey, H Bukirwa, Hasifa Bukirwa, I van den Broek, I Zongo, I Zongo, Ingrid van den Broek, Issaka Zongo, Jean-Paul Guthmann, JP Guthmann, JP Guthmann, JP Guthmann, K Mugittu, K Mugittu, K Stepniewska, K Stepniewska, Loretxu Pinoges, M Bonnet, Michel van Herp, N Bakyaita, NJ White, Pedro Pablo Palma Urruta, Piero Olliaro, PO Olliaro, RN Price, S Hamour, SG Staedke, Suna Balkan, TD Swarthout, Walter R Taylor, WJ Collins, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization   +43 more
core   +5 more sources

Effects of point mutations in Plasmodium falciparum dihydrofolate reductase and dihydropterate synthase genes on clinical outcomes and in vitro susceptibility to sulfadoxine and pyrimethamine. [PDF]

PLoS ONE, 2009
Sulfadoxine-pyrimethamine was a common first line drug therapy to treat uncomplicated falciparum malaria, but increasing therapeutic failures associated with the development of significant levels of resistance worldwide has prompted change to alternative
David J Bacon, Doug Tang, Carola Salas, Norma Roncal, Carmen Lucas, Lucia Gerena, Lorena Tapia, A Alejandro Llanos-Cuentas, Coralith Garcia, Lelv Solari, Dennis Kyle, Alan J Magill   +11 more
doaj   +1 more source

Sulfadoxine [PDF]

Definitions, 2020
A broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarial properties. Sulfadoxine competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation
openaire   +2 more sources

Intermittent Preventive Treatment of Malaria in Pregnancy: Assessment of the Sulfadoxine-Pyrimethamine Three-Dose Policy on Birth Outcomes in Rural Northern Ghana

Journal of Tropical Medicine, 2019
Background Intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) decreases placental parasitaemia and improves birth outcomes.
F. Anto, Ibrahim Haruna Agongo, V. Asoala, Elizabeth Awini, A. Oduro   +4 more
semanticscholar   +1 more source

High prevalence of double Plasmodium falciparum dhfr mutations at codons 108 and 59 in the Sistan-Baluchistan province, Iran [PDF]

, 2003
info:eu-repo/semantics ...
Bereckzy, S, Bjorkman, A, Djadid, ND, Gil, José Pedro, Zakeri, S   +4 more
core   +1 more source

The Effect of Artemisinin-Based Drugs vs Non-artemisinin-based Drugs on Gametophyte Carrying in the Body After the Treatment of Uncomplicated Falciparum Malaria: A Systematic Review and Meta-analysis

Frontiers in Pharmacology, 2022
The WHO recommends Artemisinin-based combination therapy (ACTs) as the first-line treatment for malaria. This meta-analysis aims to analyze the effects of artemisinin and its derivatives as well as non-artemisinin drugs on the gametophytes in the host ...
Yuanyuan Zou, Nadia Julie, Shiyuan Guo, Yexiao Tang, Hongying Zhang, Zhiyong Xu, Wanting Wu, Yueming Yuan, Zhibin Wu, Wenfeng Guo, Changqing Li, Xinan Huang, Qin Xu, Changsheng Deng, Jianping Song, Qi Wang, Qi Wang   +16 more
doaj   +1 more source

Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.

, 2001
Combination therapy that includes artemisinin derivatives cures most falciparum malaria infections. Lowering transmission by reducing gametocyte infectivity would be an additional benefit.
Targett, G, Drakeley, C, Jawara, M, von Seidlein, L, Coleman, R, Deen, J, Pinder, M, Doherty, T, Sutherland, C, Walraven, G, Milligan, P   +10 more
core   +1 more source

A Comparative Study of Advanced Oxidation Processes for the Removal of the Antibiotic Sulfadoxine from Water—Transformation Products and Toxicity

Applied Sciences
Sulfonamides, including sulfadoxine (SDX), are widely used antibiotics, particularly for malaria treatment. However, their extensive use has led to environmental pollution, microbial resistance, and public health risks. Advanced Oxidation Processes (AOPs)
Panagiotis A. Bizirtsakis, Kyriaki Anagnostopoulou, Vasilis C. Sarasidis, Panagiota Petsi, Alexandra Moschona, Konstantinos V. Plakas, Dimitra A. Lambropoulou   +6 more
doaj   +1 more source