Background The World Health Assembly (WHA) resolution urges African countries with a high burden of sickle cell anemia (SCA) to design and implement national programs emphasizing early identification through newborn screening (NBS) and prompt access to adequate preventive care.
Kouassi Gustave Koffi +19 more
wiley +1 more source
Frequency of Pfcrt T76 and Pfdhfr Asn-108 Drug Resistance Mutations in falciparum Malaria in Southeastern Malaria Endemic Area of Iran [PDF]
Background: Point mutations in the genes, Pfcrt and Pfdhfr, have been identified elsewhere as strongly associated with resistance to chloroquine (CQ) and pyrimethamine, respectively.
MR Razavi +5 more
doaj +1 more source
Artesunate-, sulfadoxine-, and pyrimethamine-induced cardiotoxicity
Here, we report oral artesunate, sulphadoxine and pyrimethamine (sp) induced cardio toxicity case in a female patient. Artesunate is a highly efficacious and relatively safe antimalarial drug.
Divya Goel +3 more
doaj +1 more source
Are transnational tobacco companies' market access strategies linked to economic development models? A case study of South Korea. [PDF]
Transnational tobacco companies (TTCs) have used varied strategies to access previously closed markets. Using TTCs' efforts to enter the South Korean market from the late 1980s as a case study, this article asks whether there are common patterns in these
Amon, A +21 more
core +6 more sources
Antibiotic residues and antibiotic-resistant bacteria in pig slurry used to fertilize agricultural fields [PDF]
Pig manure may contain antibiotic residues, antibiotic-resistant bacteria or pathogens, which may reach the environment upon fertilization. During this study, 69 antibiotic residues belonging to 12 classes were quantified in 89 pig slurry samples.
Colson, Lander +9 more
core +2 more sources
Unveiling Antimalarial Drug Resistance: The Role of CRISPR‐Cas Technologies in Malaria Research
Background Malaria, caused by Plasmodium parasites, remains a global health burden, with drug resistance threatening control efforts. CRISPR‐Cas technologies, particularly CRISPR‐Cas9, have transformed malaria research by enabling precise genetic manipulations to study antimalarial resistance mechanisms, develop novel therapeutics and enhance ...
Reuben Samson Dangana +3 more
wiley +1 more source
Background Exposure during pregnancy to malaria and sexually-transmitted infections is associated with adverse birth outcomes including low birth weight (LBW).
Moussa Lingani +14 more
doaj +1 more source
Introduction Fixed pigmented erythema (FPE) is a common toxidermia characterized by the appearance of one or more annular, erythematous and hyperpigmented spots, following the systemic administration of a drug. The main aim of this study was to describe the epidemiological and clinical aspects of fixed pigmented erythema at the Departmental University ...
Fabrice Akpadjan +4 more
wiley +1 more source
Background Uganda accounts for 5% of all malaria cases and deaths reported globally and, in endemic countries, pregnancy is a risk factor for both acquisition of P. falciparum infection and development of severe malaria.
Francesco Vladimiro Segala +19 more
doaj +1 more source
Therapeutic Efficacy of Sulfadoxine-Pyrimethamine and Prevalence of Resistance Markers in Tanzania Prior to Revision of Malaria Treatment Policy: Plasmodium Falciparum Dihydrofolate Reductase and Dihydropteroate Synthase Mutations in Monitoring in Vivo Resistance. [PDF]
Prior to the 2001 malarial treatment policy change in Tanzania, we conducted trials to assess the efficacy of sulfadoxine-pyrimethamine (SP) and the usefulness of molecular markers in monitoring resistance.
Abdulla, Salim +10 more
core +1 more source

