Results 61 to 70 of about 10,197 (217)

Five years of antimalarial resistance marker surveillance in Gaza Province, Mozambique, following artemisinin-based combination therapy roll out. [PDF]

PLoS ONE, 2011
Antimalarial drug resistance is a major obstacle to malaria control and eventual elimination. The routine surveillance for molecular marker of resistance is an efficient way to assess drug efficacy, which remains feasible in areas where malaria control ...
Jaishree Raman, Katya Mauff, Pedro Muianga, Abdul Mussa, Rajendra Maharaj, Karen I Barnes   +5 more
doaj   +1 more source

Sulfadoxine Resistance in Plasmodium vivax Is Associated with a Specific Amino Acid in Dihydropteroate Synthase at the Putative Sulfadoxine-Binding Site [PDF]

Antimicrobial Agents and Chemotherapy, 2004
ABSTRACT Sulfadoxine is predominantly used in combination with pyrimethamine, commonly known as Fansidar, for the treatment of Plasmodium falciparum . This combination is usually less effective against Plasmodium vivax , probably due to the innate refractoriness of parasites to the ...
Korsinczky, M., Fischer, K., Chen, N. H., Baker, J., Rieckmann, K., Cheng, Q.   +5 more
openaire   +4 more sources

Highly Water‐Stable 2D MOF as Dual Sensor for the Ultra‐Sensitive Aqueous Phase Detection of Nitrofuran Antibiotics and Organochlorine Pesticides

Small, Volume 21, Issue 3, January 22, 2025.
A chemically robust (aqueous pH = 3‐12 for a day and 3 months in water) Cd‐MOF (IITKGP‐71) is strategically developed for ultrasensitive detection of Nitrofuran (NFZ and NFT) antibiotics and DCN pesticide with high selectivity, rapid responsiveness and excellent recyclability in aqueous medium.
Supriya Mondal, Rupam Sahoo, Madhab C. Das   +2 more
wiley   +1 more source

Parasitaemia and gametocytaemia after treatment with chloroquine, pyrimethamine/sulfadoxine, and pyrimethamine/sulfadoxine combined with artesunate in young Gambians with uncomplicated malaria [PDF]

Tropical Medicine & International Health, 2001
As part of a study to assess the infectivity of gametocytes after treatment with four antimalarial regimens, the efficacy of each treatment was also determined. From September to December 1998, 598 children with uncomplicated malaria were treated; 135 received chloroquine (CQ) alone, 276 received pyrimethamine/sulfadoxine (Fansidar©, PSD) alone, 113 ...
Gijs Walraven, Rosalind Coleman, Geoffrey A. T. Targett, Geoffrey A. T. Targett, Tom Doherty, Tom Doherty, Musa Jawara, Lorenz von Seidlein, Lorenz von Seidlein   +8 more
openaire   +3 more sources

Experiences, acceptability and barriers to calcium supplementation during pregnancy in Dar es Salaam, Tanzania

Maternal &Child Nutrition, Volume 21, Issue 1, January 2025.
We assessed experiences, acceptability and barriers to higher‐dose calcium supplementation from the perspectives of pregnant women and antenatal health care providers in Dar es Salaam, Tanzania. Calcium supplementation was acceptable to pregnant women.
Emmy O. Metta, Alfa Muhihi, Heavenlight A. Paulo, Christopher R. Sudfeld, Anna Kaale, Nandita Perumal, Mary Mwanyika‐Sando, Ndeniria O. Swai, Christopher P. Duggan, Honorati Masanja, Blair J. Wylie, Andrea B. Pembe, Wafaie Fawzi   +12 more
wiley   +1 more source

Evidence of triple mutant Pfdhps ISGNGA haplotype in Plasmodium falciparum isolates from North-east India: An analysis of sulfadoxine resistant haplotype selection

Genomics Data, 2016
Background: North-east region of India has consistent role in the spread of multi drug resistant Plasmodium (P.) falciparum to other parts of Southeast Asia.
Manuj K. Das, Sumi Chetry, Mohan C. Kalita, Prafulla Dutta   +3 more
doaj   +1 more source

Efficacy of Hydroxyurea in Patients With Sickle Cell Anemia in a Low‐Income Country (Côte d’Ivoire)

Anemia, Volume 2025, Issue 1, 2025.
Background: Very few trials of hydroxyurea efficacy and safety have been conducted in sub‐Saharan Africa. We aimed to evaluate the efficacy and safety of hydroxyurea and its utility in low‐resource settings. Methods: We conducted a prospective comparative trial in patients with SCA. 128 patients were enrolled and divided into two groups.
Kouassi Gustave Koffi, Ruth Dieket, Emeraude N’dhatz, Nelly Eloise Abenan, Alexis Dohoma Silué, Ismael Kamara, Boidy Kouakou, Danho Clotaire Nanho, Duran Canatan   +8 more
wiley   +1 more source

Gestational Age–Specific Prevalence of Preeclampsia Among Pregnant Women in Ghana: A Hospital‐Based Retrospective Observational Study

BioMed Research International, Volume 2025, Issue 1, 2025.
Background: Preeclampsia is responsible for a significant rate of maternal morbidity and mortality worldwide. Gestational age as a risk factor has a significant impact on fetal outcomes in pregnancies affected by preeclampsia. However, to our knowledge, no study has identified the gestational age–specific prevalence of preeclampsia in Ghana. Thus, this
Wina Ivy Ofori Boadu, Enoch Odame Anto, Akua Benewaah Asamoah, Ezekiel Ansah, Godfred Yawson Scott, Emmanuel Ekow Korsah, Joseph Frimpong, Valentine Christian Kodzo Tsatsu Tamakloe, Michael Nyantakyi, Agartha Odame Anto, Emmanuel Timmy Donkoh, Kwame Ofori Boadu, Richard Vikpebah Duneeh, Frederick Ayensu, Christian Obirikorang, Wittaya Chaiwangyen   +15 more
wiley   +1 more source

Comparative Evaluation of the Dynamics of Parameters of Cell-Mediated Immunity under the Influence of Different Therapies for Chronic Acquired Toxoplasmosis

Aktualʹnaâ Infektologiâ, 2015
The article presents a comparative evaluation of the dynamics of parameters of cell-mediated immunity in patients under the influence of different therapies for chronic acquired toxoplasmosis (CAT).
O.V. Bobrova, Anuar al Hatib
doaj   +1 more source

Therapeutic efficacy of sulfadoxine-pyrimethamine for Plasmodium falciparum malaria.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2005
To assess the therapeutic efficacy of sulfadoxinepyrimethamine (SP) after 5 years of use as first-line treatment of uncomplicated Plasmodium falciparum malaria, and thus guide the selection of artemisinin-based combination therapy in Mpumalanga, South Africa.An open-label, in vivo therapeutic efficacy study of patients with uncomplicated P.
Mabuza, Aaron, Govere, John, La Grange, Kobus, Mngomezulu, Nicros, Allen, Elizabeth, Zitha, Alpheus, Mbokazi, Frans, Durrheim, David, Barnes, Karen   +8 more
openaire   +4 more sources