Results 71 to 80 of about 21,364 (252)

Miniaturized green liquid‐phase sample pre‐concentration methods for pharmaceutical drugs assessment in wastewater

Water and Environment Journal, Volume 39, Issue 2, Page 143-167, May 2025.
Abstract Microextraction methods such as hollow fibre‐liquid phase microextraction (HF‐LPME), dispersive liquid–liquid microextraction (DLLME), single‐drop microextraction (SDME) and ultrasound‐assisted emulsification microextraction (USAEME) have become prominent for analysing pharmaceuticals in wastewater. HF‐LPME, particularly the three‐phase system,
Bavuyile Magqira, Precious Mahlambi
wiley   +1 more source

Community-based Malaria Screening and Treatment for Pregnant Women Receiving Standard Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: A Multicenter (The Gambia, Burkina Faso, and Benin) Cluster-randomized Controlled Trial

Clinical Infectious Diseases, 2018
Adding community-based scheduled malaria screening and treatment to existing intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) strategies did not reduce malaria in pregnancy.
Susana Umberto Lindsay John Kalifa Simon Fanta Halidou Ma Scott D’Alessandro Kendall Bradley Bojang Correa N, S. Scott, U. d’Alessandro, L. Kendall, J. Bradley, K. Bojang, Simon Correa, F. Njie, H. Tinto, M. Traoré-Coulibaly, H. M. Natama, O. Traoré, I. Valéa, A. Nahum, Daniel Ahounou, Francis Bohissou, G. Sondjo, Carine Agbowai, P. Mens, E. Ruizendaal, H. Schallig, Susan Dierickx, K. P. Grietens, L. Duval, L. Conteh, M. Drabo, J. Guth, F. Pagnoni   +27 more
semanticscholar   +1 more source

Responsiveness of emergency obstetric care systems in low- and middle-income countries: a critical review of the "third delay". [PDF]

, 2012
We reviewed the evidence on the duration, causes and effects of delays in providing emergency obstetric care to women attending health facilities (the third delay) in low- and middle-income countries. We performed a critical literature review using terms
Cavallaro, Francesca L, Marchant, Tanya J   +1 more
core   +1 more source

Use of population pharmacokinetic‐pharmacodynamic modelling to inform antimalarial dose optimization in infants

British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 968-980, April 2025.
Infants bear a significant malaria burden but are usually excluded from participating in early dose optimization studies that inform dosing regimens of antimalarial therapy. Unlike older children, infants' exclusion from early‐phase trials has resulted in limited evidence to guide accurate dosing of antimalarial treatment for uncomplicated malaria or ...
Clifford G. Banda, Joel Tarning, Karen I. Barnes   +2 more
wiley   +1 more source

Prevalence of Plasmodium falciparum parasites resistant to sulfadoxine/pyrimethamine in the Democratic Republic of the Congo: emergence of highly resistant pfdhfr/pfdhps alleles

Journal of Antimicrobial Chemotherapy, 2018
Background In 2005, the Democratic Republic of the Congo (DRC) switched to artesunate/amodiaquine as the first-line antimalarial in response to increasing sulfadoxine/pyrimethamine resistance and adopted intermittent preventive treatment using ...
P. Nkoli Mandoko, Florent Rouvier, Lebon Matendo Kakina, D. Moke Mbongi, Christine Latour, J. Losimba Likwela, D. Ngoyi Mumba, S. K. Bi Shamamba, Jean-Jacques Tamfum Muyembe, L. Muepu Tshilolo, D. Parzy, V. Sinou   +11 more
semanticscholar   +1 more source

Assessment of a national voucher scheme to deliver insecticide-treated mosquito nets to pregnant women.

, 2010
BACKGROUND: The benefits of a health-related intervention may be compromised by the challenges of delivering the intervention on a large scale. We analyzed the process involved in the Tanzania National Voucher Scheme, a system for delivering insecticide ...
Armstrong-Schellenberg, Joanna, Bruce, Jane, Hanson, Kara, Jones, Caroline, Marchant, Tanya, Mponda, Hadji, Nathan, Rose, Schellenberg, David, Sedekia, Yovitha   +8 more
core   +2 more sources

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. [PDF]

, 2014
Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and P.
Adam, Ishag, Ademowo, George, Arze, Cesar, Asaq Molecular Marker Study Group, Baliraine, Frederick N, Berens-Riha, Nicole, Björkman, Anders, Borrmann, Steffen, Checchi, Francesco, Dahal, Prabin, Davis, Timothy ME, Desai, Meghna, Dhorda, Mehul, Djimdé, Abdoulaye A, Dorsey, Grant, El-Sayed, Badria B, Eshetu, Teferi, Eyase, Frederick, Falade, Catherine, Faucher, Jean-François, Fröberg, Gabrielle, Gadalla, Nahla B, Grivoyannis, Anastasia, Guérin, Philippe, Hamour, Sally, Houzé, Sandrine, Johnson, Jacob, Kamugisha, Erasmus, Kariuki, Simon, Kiechel, Jean-René, Kironde, Fred, Kofoed, Poul-Erik, LeBras, Jacques, Malmberg, Maja, Moriera, Clarissa, Mwai, Leah, Mårtensson, Andreas, Ménard, Didier, Ngasala, Billy, Nosten, Francois, Nsanzabana, Christian, Nsobya, Samuel L, Nzila, Alexis, Oguike, Mary, Ogutu, Bernhards, Otienoburu, Sabina Dahlström, Ouédraogo, Jean-Bosco, Piola, Patrice, Plowe, Christopher V, Price, Ric N, Rombo, Lars, Rosenthal, Philip J, Schramm, Birgit, Sibley, Carol Hopkins, Somé, A Fabrice, Stepniewska, Kasia, Sutherland, Colin J, Thwing, Julie, Ursing, Johan, Venkatesan, Meera, Wong, Rina PM, Zeynudin, Ahmed, Zongo, Issaka   +62 more
core   +3 more sources

Pharmacokinetics of a Novel Piperaquine Dispersible Granules Formulation Under Fasting and Various Fed Conditions Versus Piperaquine Tablets When Fasted in Healthy Tanzanian Adults: A Randomized, Phase I Study

Clinical and Translational Science, Volume 18, Issue 2, February 2025.
ABSTRACT Piperaquine tetraphosphate (PQP), a long‐acting antimalarial, is being considered in a combination for chemoprevention. Dihydroartemisinin‐piperaquine tablets (hard and dispersible) approved for the treatment of acute uncomplicated malaria should be administered in a fasted state, as PQP bioavailability increases with food.
Florence A. Milando, Said Jongo, Salim Abdulla, Gloria Nyaulingo, Anneth‐Mwasi Tumbo, Sarah Mswata, Juliether Tiago, Beatus S. Bongole, Ashura Mirambo, Kamaka Kassimu, Hussein Mbarak, Mohammed A. Rashid, Ali Hamad, Michael Mihayo, Tunu Ndanzi, Omary Zuberi, Naima Saadia, Mariam Somboka, Mariam Yamba‐Yamba, Theresia Ngonyani, Amina Nditi, Margaret Msuya, Bakari Mwalimu, Hajirani M. Msuya, Khamis Awadh, Ali Ali, Anne Claire Marrast, Denis Gossen, Alice Neequaye, Myriam El‐Gaaloul, Hanu Ramachandruni, Isabelle Borghini‐Fuhrer   +31 more
wiley   +1 more source

Organometallic Conjugates of the Drug Sulfadoxine for Combatting Antimicrobial Resistance.

Chemistry, 2018
Fourteen novel arene RuII , and cyclopentadienyl (Cpx ) RhIII and IrIII complexes containing an N,N'-chelated pyridylimino- or quinolylimino ligand functionalized with the antimalarial drug sulfadoxine have been synthesized and characterized, including ...
P. Chellan, V. Avery, Sandra Duffy, J. Triccas, Gayathri Nagalingam, Christina C Tam, Luisa W Cheng, Jenny Liu, K. Land, G. Clarkson, I. Romero‐Canelón, P. Sadler   +11 more
semanticscholar   +1 more source

Can field-based mosquito feeding assays be used for evaluating transmission-blocking interventions? [PDF]

, 2012
A recent meta-analysis of mosquito feeding assays to determine the Plasmodium falciparum transmission potential of naturally infected gametocyte carriers highlighted considerable variation in transmission efficiency between assay methodologies and ...
Bousema, Teun, Churcher, Thomas S, Dinglasan, Rhoel R, Morlais, Isabelle   +3 more
core   +8 more sources