Results 51 to 60 of about 4,042 (165)
Intramolecular amidation of sulfamates catalyzed by metalloporphyrins [PDF]
, 2004 An intramolecular amidation processes for substrates such as sulfamates using chiral and non-chiral metalloporphyrin complexes which can maximize catalytic activity, enhance efficiency, stereoselectivity and speed of amidation reactions is described. The
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Scavestrogen sulfamates: correlation between estrone sulfatase inhibiting and antioxidant effects
, 1998 In the present study estrone sulfatase (steryl-sulfatase; EC 3.1.6.2) and phenylsulfatase (arylsulfatase B; EC 3.1.6.1) inhibiting as well as antioxidant effects exerted by ring B,C unsaturated sulfamates of estrone (J 1025), 17 beta -estradiol (J 1054,
Wolfgang Römer +2 more
core +1 more source
Alcohol‐Directed Carboamination of Conjugated Enynes
Angewandte Chemie, Volume 138, Issue 24, 8 June 2026.The first general three‐component intermolecular Pd‐catalyzed carboamination of conjugated enynes enables the coupling of anilines and aryl triflates to produce functionalized allenic amines, utilizing a native alcohol directing group to control regioselectivity.
Helena Solé‐Àvila +3 more
wiley +2 more sources
MoleculesA small library of 79 substituted phenylsulfonamidoalkyl sulfamates, 1b–79b, was synthesized starting from arylsulfonyl chlorides and amino alcohols with different numbers of methylene groups between the hydroxyl and amino moieties yielding intermediates
Toni C. Denner +3 more
doaj +1 more source
European journal of medicinal chemistry, 2019 Four new series of aromatic sulfamates were synthesized and investigated for the inhibition of four human (h) isoforms of zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1), hCA I, II, IX, and XII.
D. Moi +5 more
semanticscholar +1 more source
Intramolecular Amidation Of Sulfamates Catalyzed By Metalloporphyrins [PDF]
, 2006 An Intramolecular Amidation Processes For Substrates Such As Sulfamates Using Chiral And Non-Chiral Metalloporphyrin Complexes Which Can Maximize Catalytic Activity, Enhance Efficiency, Stereoselectivity And Speed Of Amidation Reactions Is Described. The
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An Efficient Method for the Synthesis of Benzofused Five-Membered Cyclic Sulfamates
Журнал органічної та фармацевтичної хіміїAn efficient and scalable method for the synthesis of 1,2,3-benzoxathiazole 2,2-dioxides and related five-membered cyclic sulfamates employing gaseous sulfuryl fluoride (SO2F2) in the presence of Et3N is described.
Serhii H. Aleksandrenko +1 more
doaj +1 more source
Arylsulfonamido-alkyl-sulfamates act as inhibitors of bovine carbonic anhydrase II
European Journal of Medicinal Chemistry ReportsA small library of arylsulfonamido-alkyl sulfamates was prepared by a two-step synthesis from readily available starting materials. The compounds were tested for their ability to inhibit bovine carbonic anhydrase II.
Toni C. Denner +2 more
doaj +1 more source
Legionella pneumophila Carbonic Anhydrases: Underexplored Antibacterial Drug Targets
Pathogens, 2016 Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes which catalyze the hydration of carbon dioxide to bicarbonate and protons. Many pathogenic bacteria encode such enzymes belonging to the α-, β-, and/or γ-CA families.
Claudiu T. Supuran
doaj +1 more source
Optimization of novel compounds using computer‐aided drug design for treatment of cardiac arrhythmia
British Journal of Pharmacology, Volume 183, Issue 17, Page 5407-5420, September 2026.Background and Purpose Loss‐of‐function mutations of the voltage‐gated Kv7.1 (KCNQ/KCNE1) channels lead to cardiac arrhythmia such as long QT syndrome, characterized by a prolonged QT interval . One strategy to correct the prolonged QT interval is to design molecules that activate KCNQ1/KCNE1 channels and restore the QT interval.
Jessica Jowais +4 more
wiley +1 more source