Results 41 to 50 of about 31,137 (305)
Molecules, 2023 For nearly 30 years, resveratrol has attracted the scientific community’s interest. This has happened thanks to the so-called French paradox, that is, the paradoxically low mortality from cardiovascular causes in the French population despite a diet rich
Izabela Szymkowiak +2 more
doaj +1 more source
Sulfatase 1 and sulfatase 2 as novel regulators of macrophage antigen presentation and phagocytosis [PDF]
Yeungnam University Journal of Medicine, 2021 Background Sulfation of heparan sulfate proteoglycans (HSPGs) is critical for the binding and signaling of ligands that mediate inflammation. Extracellular 6-O-endosulfatases regulate posttranslational sulfation levels and patterns of HSPGs.
Hyun-Je Kim +2 more
doaj +1 more source
Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model. [PDF]
, 2011 The efficacy of resveratrol as a preventive agent against the growth of t(4;11) acute lymphoblastic leukemia (ALL) was evaluated in NOD.CB17-Prkdcscid/J mice engrafted with the human t(4;11) ALL SEM cell line.
Ducore, Jonathan M +5 more
core +1 more source
A phase 1/2 study of intrathecal heparan-N-sulfatase in patients with mucopolysaccharidosis IIIA
Molecular Genetics and Metabolism, 2016 Jan Pieter Marchal, Luying Pan
exaly +2 more sources
Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity
Frontiers in Oncology, 2019 Membrane heparan sulfate proteoglycans (HSPG) regulate cell proliferation, migration, and differentiation and are therefore considered key players in cancer cell development processes.
Jlenia Brunetti +9 more
doaj +1 more source
Profiling Urinary Sulfate Metabolites With Mass Spectrometry
Frontiers in Molecular Biosciences, 2022 The study of urinary phase II sulfate metabolites is central to understanding the role and fate of endogenous and exogenous compounds in biological systems.
Christopher C. J. Fitzgerald +8 more
doaj +1 more source
The pmrCAB Operon Mediates Polymyxin Resistance In Acinetobacter Baumannii ATCC 17978 And Clinical Isolates Through Phosphoethanolamine Modification Of Lipid A [PDF]
, 2011 The emergence of multidrug resistance among Acinetobacter baumannii is leading to an increasing dependence on the use of polymyxins as last-hope antibiotics. Here, we utilized genetic and biochemical methods to define the involvement of the pmrCAB operon
Arroyo, Luis A. +5 more
core +2 more sources
Molecular Cancer, 2005 Hsulf-1 is a newly identified enzyme, which has the ability to decrease the growth of hepatocellular, ovarian, and head and neck squamous cell carcinoma cells by interfering with heparin-binding growth factor signaling.
Giese Nathalia A +8 more
doaj +1 more source
Post-synthetic regulation of HS structure: the yin and yang of the Sulfs in Cancer
Frontiers in Oncology, 2014 Heparan sulfate (HS) is a complex polysaccharide that takes part in most major cellular processes, through its ability to bind and modulate a very large array of proteins.
Romain R Vives +2 more
doaj +1 more source
Journal of Inherited Metabolic Disease, 2020 Multiple Sulfatase Deficiency (MSD, MIM#272200) is an ultra‐rare lysosomal storage disorder arising from mutations in the SUMF1 gene, which encodes the formylglycine‐generating enzyme (FGE).
Lars Schlotawa +6 more
semanticscholar +1 more source