Results 71 to 80 of about 28,914 (292)

Quantification of Dehydroepiandrosterone, 17β-Estradiol, Testosterone, and Their Sulfates in Mouse Tissues by LC-MS/MS. [PDF]

, 2019
We report a high-performance, liquid chromatography/tandem mass spectrometry (HPLC-MS/MS) assay to quantify without derivatizaton dehyroepiandrosterone (DHEA), 17β-estradiol (E2), testosterone (T), and their sulfates in serum and tissues.
Napoli, Joseph L, Yoo, Hong Sik
core  

Antitumor activity of sulforaphane in mice model of skin cancer via blocking sulfatase‐2

Experimental Dermatology, 2018
Although there are many treatment options for skin cancer, the chemotherapeutic agents for skin cancer are linked with many adverse effects as well as the development of multidrug resistance.
A. Alyoussef, M. Taha
semanticscholar   +1 more source

Development of steroid sulfatase inhibitors [PDF]

Molecular and Cellular Endocrinology, 2011
Hydrolysis of biologically inactive steroid sulfates to unconjugated steroids by steroid sulfatase (STS) is strongly implicated in rendering estrogenic stimulation to hormone-dependent cancers such as those of the breast. Considerable progress has been made in the past two decades with regard to the discovery, design and development of STS inhibitors ...
Woo, L. W. L., Purohit, A., Potter, B. V. L.   +2 more
openaire   +3 more sources

A clinical case of physical therapy of a child with multiple sulfatase deficiency

Medičnì Perspektivi, 2021
The article deals with the problems of physical therapy in children with multiple sulfatase deficiency (MSD). The purpose of the study presented in the article was to substantiate the need to form a structured, personalized comprehensive rehabilitation ...
I.M. Grygus, O.B. Nagorna, N.E. Nesterchuk, A.O. Nogas, P.S. Podoliaka, T.V. Gamma   +5 more
doaj   +1 more source

Recommendations for the management of MPS VI: systematic evidence- and consensus-based guidance. [PDF]

, 2019
IntroductionMucopolysaccharidosis (MPS) VI or Maroteaux-Lamy syndrome (253200) is an autosomal recessive lysosomal storage disorder caused by deficiency in N-acetylgalactosamine-4-sulfatase (arylsulfatase B).
Akyol, Mehmet Umut, Alden, Tord D, Amartino, Hernan, Ashworth, Jane, Belani, Kumar, Berger, Kenneth I, Borgo, Andrea, Braunlin, Elizabeth, Eto, Yoshikatsu, Giugliani, Roberto, Gold, Jeffrey I, Harmatz, Paul, Hendriksz, Christian, Jester, Andrea, Jones, Simon A, Karsli, Cengiz, Mackenzie, William, Marinho, Diane Ruschel, McFadyen, Andrew, McGill, Jim, Mitchell, John J, MPS Consensus Programme Co-Chairs, MPS Consensus Programme Steering Committee, Muenzer, Joseph, Okuyama, Torayuki, Orchard, Paul J, Scarpa, Maurizio, Stevens, Bob, Thomas, Sophie, Walker, Robert, Wynn, Robert   +30 more
core  

Severe neonatal multiple sulfatase deficiency presenting with hydrops fetalis in a preterm birth patient

JIMD Reports, 2019
Multiple sulfatase deficiency (MSD) is an ultra‐rare lysosomal storage disorder (LSD). Mutations in the SUMF1 gene encoding the formylglycine generating enzyme (FGE) result in an unstable FGE protein with reduced enzymatic activity, thereby affecting the
Lars Schlotawa, T. Dierks, Sophie Christoph, E. Cloppenburg, A. Ohlenbusch, G. Christoph Korenke, J. Gärtner   +6 more
semanticscholar   +1 more source

Enrichable consortia of microbial symbionts degrade macroalgal polysaccharides in Kyphosus fish

mBio
Coastal herbivorous fishes consume macroalgae, which is then degraded by microbes along their digestive tract. However, there is scarce genomic information about the microbiota that perform this degradation.
Aaron Oliver, Sheila Podell, Linda Wegley Kelly, Wesley J. Sparagon, Alvaro M. Plominsky, Robert S. Nelson, Lieve M. L. Laurens, Simona Augyte, Neil A. Sims, Craig E. Nelson, Eric E. Allen   +10 more
doaj   +1 more source

Inhibition of Morphogenetic Movement duringXenopusGastrulation by Injected Sulfatase: Implications for Anteroposterior and Dorsoventral Axis Formation [PDF]

, 1997
In order to explore the role of morphogenetic movement in the establishment of anteroposterior and dorsoventral axes, we sought to identify novelin vivoinhibitors of gastrulation movements inXenopus laevis.Injection of hydrolytic sulfatase into the ...
Danilchik, Michael V., Sater, Amy K., Uzman, J.Akif, Wallingford, John B.   +3 more
core   +1 more source

Transcriptional Induction of Periostin by a Sulfatase 2-TGFβ1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma.

Cancer Research, 2017
Existing antiangiogenic approaches to treat metastatic hepatocellular carcinoma (HCC) are weakly effectual, prompting further study of tumor angiogenesis in this disease setting.
Gang Chen, I. Nakamura, R. Dhanasekaran, Eriko Iguchi, Ezequiel J Tolosa, P. Romecín, Renzo E Vera, Luciana L Almada, Alexander G. Miamen, R. Chaiteerakij, Mengtao Zhou, M. Asiedu, C. Moser, Shaoshan Han, Chunling Hu, B. Banini, A. Oseini, Yichun Chen, Yong Fang, Dongye Yang, Hassan M. Shaleh, Shaoqing Wang, Dehai Wu, T. Song, Ju-Seog Lee, S. Thorgeirsson, É. Chevet, V. Shah, M. Fernandez-Zapico, L. Roberts   +29 more
semanticscholar   +1 more source

Sulfatases are determinants of alveolar formation [PDF]

Matrix Biology, 2012
Alveolar formation or alveolarization is orchestrated by a finely regulated and complex interaction between growth factors and extracellular matrix proteins. The lung parenchyma contains various extracellular matrix proteins including proteoglycans, which are composed of glycosaminoglycans (GAGs) linked to a protein core.
Arteaga Solis E, SETTEMBRE, CARMINE, BALLABIO, ANDREA, Karsenty G.   +3 more
openaire   +4 more sources