Results 71 to 80 of about 27,389 (268)

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Appraisal of Industrial Pollutants in Sewage and Biogas Production Using Multivariate Analysis and Unsupervised Machine Learning Clustering

Applied Sciences
Sewage composition analysis is important for understanding environmental impact and ensuring effective treatment processes. In this study, we employed multivariate analysis techniques to delve into the intricate composition of sewage.
Wiktor Halecki, Anna Młyńska, Krzysztof Chmielowski   +2 more
doaj   +1 more source

ALUMOSULFATE-PHOSPHATES IN THE CRYSTAL-BEARING VEINS OF THE ZHELANNINSKOE ORE FIELD (SUBPOLAR URALS) [PDF]

Минералогия, 2015
Lazulite, skortzalite, svanbergite, augelite, turquoise, and krandallite from quartz veins of the Zhelanninskoe ore field, Subpolar Urals, and stages of mineral formation are characterized.
S.A. Repina, V.I. Popova
doaj  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Features of Authigenic Mineralization and Geochemical Processes of Fossilization of Marine Reptile Vertebrae (Oxford-Kimmeridge, Republic of Tatarstan)

Georesursy
Studies were conducted on the sequence and conditions of authigenic mineral formation in fossil bone tissue, as well as the chemical composition and geochemical characteristics of fossilization processes in marine reptile vertebrae discovered in ...
M. S. Glukhov, О. P. Shilovsky, А. R. Gainanova, А. I. Mullakaev   +3 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Isotypism and phase transitions of (NH4)M(HSO4)(SO4)(H2O)2 (M = Fe, Co and Ni) compounds

Acta Crystallographica Section E: Crystallographic Communications
A systematic crystallization study of {(NH4)[M(HSO4)(SO4)(H2O)2]}n compounds, catena-poly[ammonium [[diaquametal(II)]-μ-(hydrogen sulfato)-μ-sulfato]], revealed that crystals of the M = Fe, Co and Ni members could be grown by evaporation of mixed ...
Matthias Weil
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source