Results 71 to 80 of about 1,697 (218)

ALUMOSULFATE-PHOSPHATES IN THE CRYSTAL-BEARING VEINS OF THE ZHELANNINSKOE ORE FIELD (SUBPOLAR URALS) [PDF]

Минералогия, 2015
Lazulite, skortzalite, svanbergite, augelite, turquoise, and krandallite from quartz veins of the Zhelanninskoe ore field, Subpolar Urals, and stages of mineral formation are characterized.
S.A. Repina, V.I. Popova
doaj  

Dimethyl sulfate and diisopropyl sulfate as practical and versatile O-sulfation reagents

Nature Communications
AbstractO-Sulfation is a vital post-translational modification in bioactive molecules, yet there are significant challenges with their synthesis. Dialkyl sulfates, such as dimethyl sulfate and diisopropyl sulfate are commonly used as alkylation agents in alkaline conditions, and result in the formation of sulfate byproducts.
Shuaishuai Yue, Guoping Ding, Ye Zheng, Chunlan Song, Peng Xu, Biao Yu, Jiakun Li   +6 more
openaire   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Appraisal of Industrial Pollutants in Sewage and Biogas Production Using Multivariate Analysis and Unsupervised Machine Learning Clustering

Applied Sciences
Sewage composition analysis is important for understanding environmental impact and ensuring effective treatment processes. In this study, we employed multivariate analysis techniques to delve into the intricate composition of sewage.
Wiktor Halecki, Anna Młyńska, Krzysztof Chmielowski   +2 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Isotypism and phase transitions of (NH4)M(HSO4)(SO4)(H2O)2 (M = Fe, Co and Ni) compounds

Acta Crystallographica Section E: Crystallographic Communications
A systematic crystallization study of {(NH4)[M(HSO4)(SO4)(H2O)2]}n compounds, catena-poly[ammonium [[diaquametal(II)]-μ-(hydrogen sulfato)-μ-sulfato]], revealed that crystals of the M = Fe, Co and Ni members could be grown by evaporation of mixed ...
Matthias Weil
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Features of Authigenic Mineralization and Geochemical Processes of Fossilization of Marine Reptile Vertebrae (Oxford-Kimmeridge, Republic of Tatarstan)

Georesursy
Studies were conducted on the sequence and conditions of authigenic mineral formation in fossil bone tissue, as well as the chemical composition and geochemical characteristics of fossilization processes in marine reptile vertebrae discovered in ...
M. S. Glukhov, О. P. Shilovsky, А. R. Gainanova, А. I. Mullakaev   +3 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source