Results 81 to 90 of about 45,956 (313)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
FXIIa activity in presence of β-1,3-glucan sulfates.
, 2016 FXIIa was incubated with a) curdlan sulfates (CurS) or b) phycarin sulfates (PhyS) for 10 min at 37°C. Then, its amidolytic activity was measured using S-2302. The dashed line marks the positive control in absence of test compound.
Susanne Alban (2339212) +2 more
core +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Preparation and Characterization of Protocatechuic Acid Sulfates
Molecules, 2019 Protocatechuic acid (3,4-dihydroxybenzoic acid; PCA) is a phenolic acid present in plants as a secondary metabolite and is also produced in the human organism as a metabolite from the degradation of polyphenols by the intestinal microbiota, particularly ...
Sofia M. Gutierrez-Zetina +4 more
doaj +1 more source
Les Sulfates des Valettes (Valais)
, 1987 Etude du site des Valettes, près de Sembrancher en Valais. Découverte de plusieurs sulfates de zinc nouveaux pour la Suisse et, en particulier, de la zincocopiapite, seconde occurrence ...
Meisser, Nicolas, Perroud, Pierre
core
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
BuildingsThis study evaluates the impact of the addition of nanoparticles of anodic manganese dioxide (NAMD) on the mechanical properties and resistance to chemical attack of concrete.
Ana Torre +6 more
doaj +1 more source
(Table 1) Lithologic description and stable isotope composition of sulfates at ODP Leg 107 sites
, 1990 (Table 1) Lithologic description and stable isotope composition of sulfates at ODP Leg 107 ...
Pierre, Catherine +5 more
core +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Marine Drugs, 2015 Codium fragile and Chondrus crispus are, respectively, green and red seaweeds which are abundant along the North Atlantic coasts. We investigated the chemical composition and antiviral activity of enzymatic extracts of C. fragile (CF) and C. crispus (CC).
Garima Kulshreshtha +7 more
doaj +1 more source