Results 81 to 90 of about 1,697 (218)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

EFFECT OF SOIL POTASSIUM LEVELS AND DIFFERENT POTASSIUM FERTILIZERS ON YIELD, MACROELEMENT AND CHLORIDE NUTRION STATUS OF APPLE TREES IN FULL FRUITION PERIOD

Acta Scientiarum Polonorum: Hortorum Cultus, 2011
The experiment was established in the spring 1999 on lessive soil developed from light boulder clay. Apple trees of Golden Delicious cv. on M.26 rootstock were planted in 3.5 × 1.2 m (2381 trees·ha-1) spacing. Research involved the effect of diversified 
Adam Szewczuk, Andrzej Komosa, Ewelina Gudarowska   +2 more
doaj  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Revisiting three minerals from Cioclovina Cave (Romania)

International Journal of Speleology, 2011
Cioclovina Cave in Romania’s Southern Carpathians is a world-renowned cave site for its paleontological, anthropological, andmineralogical (type locality of ardealite) finds.
Onac Bogdan P., Effenberger Herta S., Collins Nathan C., Kearns Joe B., Breban Radu C.   +4 more
doaj  

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

ALTERACIÓN QUÍMICA DE LA SOLUCIÓN DE UN SUELO SULFATADO ÁCIDO, CON ENCALAMIENTO Y LAVADO EN COLUMNA DISTURBADAS ALTERATION OF ACID SULPHATE SOIL SOLUTION CHEMISTRY WITH LIMING AND WASHING IN DISTURBED COLUMNS

Revista U.D.C.A Actualidad & Divulgación Científica, 2009
La acidez de los suelos es uno de los principales factores que limitan la producción de los suelos sulfatados ácidos tropicales, siendo lenta la corrección con cal agrícola y lavado.
Enrique Combatt Caballero, Teobaldis Mercado Fernández, Graciliano Palencia Severiche   +2 more
doaj  

Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies

Advanced Engineering Materials, EarlyView.
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo, Daniela Winsley Valereto Friozi, Vinícius de Oliveira, Marcia Cristina Branciforti   +3 more
wiley   +1 more source

Heparan sulfates and heparan sulfate proteoglycans in hematopoiesis

Blood
Abstract From signaling mediators in stem cells to markers of differentiation and lineage commitment to facilitators for the entry of viruses, such as HIV-1, cell surface heparan sulfate (HS) glycans with distinct modification patterns play important roles in hematopoietic biology.
Richard T. Piszczatowski, Hannes E. Bülow, Ulrich Steidl   +2 more
openaire   +2 more sources