Antiulcer activity of Muntingia calabura leaves involves the modulation of endogenous nitric oxide and nonprotein sulfhydryl compounds [PDF]
Context: Muntingia calabura L. (Muntingiaceae) is a native plant species of the American continent and is widely cultivated in warm areas in Asia, including Malaysia. The plant is traditionally used to relieve pain from gastric ulcers.
Ahmad, Zuraini+6 more
core +1 more source
Advances on Albumin‐Based Carriers for Anticancer Drug Delivery
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou+4 more
wiley +1 more source
Pharmacology and clinical drug candidates in redox medicine [PDF]
SIGNIFICANCE Oxidative stress is suggested to be a disease mechanism common to a wide range of disorders affecting human health. However, so far, the pharmacotherapeutic exploitation of this, for example, based on chemical scavenging of pro-oxidant ...
Casas, Ana I+11 more
core +2 more sources
Detoxicant and hepatoprotective effect of cystamine dihydrochlorid in acute intoxication by carbone tetrachloride [PDF]
It is known, that level of sulfhydryl groups (SH-groups) is one of the important factors determining the liver sensitivity to damaging effect of halogenated hydrocarbons, alkylating, and other hepatotropic compounds. When you are citing the document, use
German, O.M.+7 more
core
A Small Molecule Inhibitor of Redox-Regulated Protein Translocation into Mitochondria [PDF]
SummaryThe mitochondrial disulfide relay system of Mia40 and Erv1/ALR facilitates import of the small translocase of the inner membrane (Tim) proteins and cysteine-rich proteins.
Dabir, Deepa V.+9 more
core +1 more source
Redirecting the Peptide Cleavage Causes Protease Inactivation
Cysteine and serine proteases cleave peptides through covalent catalysis by generating a transient adduct with the N‐terminal part of the substrate after releasing its C‐terminal part. We demonstrate the unique redirection of this event leading to strong enzyme inactivation.
Michael Gütschow+20 more
wiley +1 more source
High pressure high temperature (HPHT) synthesis and magnetism of MSr2Y1.5Ce0.5Cu2O10 compounds with M = Ru, Mn, and Cr [PDF]
The M-1222 compounds are synthesized in near single phase form. These compounds crystallise in I4/mmm Tetragonal structure. None of the studied compound is superconducting but they asre weakly magnetic. This is first report on synthesis of Cr and Mn -1222 compounds.
arxiv
Accurate high-throughput screening of I-II-V 8-electron Half-Heusler compounds for renewable-energy applications [PDF]
Renewable energy resources have emerged as the best alternatives to fossil fuel energy which are rapidly declining with time. Here, eight valence-electron count Half-Heusler(HH) alloys have been studied using reliable first principles calculations in the search of potential candidates for renewable energy applications like thermoelectric (TE), solar ...
arxiv +1 more source
The preventive role of ultraviolet radiation during exposure to ionizing radiation [PDF]
The effect of suberythematous doses of ultraviolet and ionizing radiation on sulfhydryl groups, cholesterol and hemoglobin of the blood is ...
Yatsula, G. S.
core +1 more source
Anchoring of Surface Proteins to the Cell Wall of Staphylococcus aureus. III. Lipid II is an in vivo peptidoglycan substrate for sortase-catalyzed surface protein anchoring [PDF]
Surface proteins of Staphylococcus aureus are anchored to the cell wall peptidoglycan by a mechanism requiring a C-terminal sorting signal with an LPXTG motif.
Mazmanian, Sarkis K.+3 more
core