Results 141 to 150 of about 1,607,740 (290)

Interaction of naphthomycin A with sulfhydryl compounds.

open access: yesThe Journal of Antibiotics, 1986
T, Okabe   +5 more
openaire   +3 more sources

Machine Learning‐Enhanced Ultrasensitive Immuno‐CRISPR Array Facilitates Early Diagnosis of Alzheimer's Disease by Detecting Multiple Plasma Biomarkers

open access: yesAdvanced Science, Volume 13, Issue 49, 3 September 2026.
This work presents a CRISPR‐based, ultrasensitive multiplex protein detection array capable of simultaneously analyzing six plasma biomarkers associated with Alzheimer's disease (AD). By integrating antibody‐mediated signal transduction, recombinase polymerase amplification, and spatially encoded CRISPR‐Cas12a, the system achieves detection sensitivity
Liding Zhang   +9 more
wiley   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao   +11 more
wiley   +1 more source

Engineered Au@CeO2 Hybrid Nanoparticles With Microenvironment Dependent Self‐Adjustability for Integration of Tumor‐Specific Photothermal‐Chemodynamic Therapy and Inflammation Prevention

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
An intelligent Au@CeO2 Hybrid Nanoparticles (ACEF) with microenvironment‐dependent self‐adjustability was engineered to not only perform efficient and tumor‐specific photothermal‐chemodynamic therapy for precise tumor elimination, but also serve as a ROS scavenger in healthy tissues around the tumor to avoid the unexpected oxidative damage and ...
Wenyun Mu   +8 more
wiley   +1 more source

Bio‐Based Polyurethanes for Sustainable and Multifunctional Applications

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
Bio‐based polyurethanes prepared from vegetable oils, lignin, and polysaccharides have attracted increasing interest as alternatives to fossil‐derived polyurethanes. This review summarizes recent progress in their chemistry, structural engineering, and advanced applications, highlighting the roles of feedstocks, chain‐segment design, dynamic covalent ...
Xin Li   +6 more
wiley   +1 more source

Cytotoxic and Immunological Effects of Terpinolene and 1‐butyl‐3,4‐methylenedioxybenzene on Aedes aegypti Larvae

open access: yesArchives of Insect Biochemistry and Physiology, Volume 123, Issue 1, September 2026.
The terpinolene + BMDB association caused severe midgut damage, increased apoptosis, reduced proliferation, and immune suppression in Ae. aegypti larvae, indicating that sublethal effects, despite higher LC50, compromise larval recovery and represent a promising strategy for integrated vector management.
Maria Clara da Nóbrega Ferreira Fernandes   +9 more
wiley   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

open access: yesBMEMat, Volume 4, Issue 3, September 2026.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang   +7 more
wiley   +1 more source

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