Results 171 to 180 of about 68,767 (278)

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin   +7 more
wiley   +1 more source

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

open access: yesMedicinal Research Reviews, Volume 45, Issue 4, Page 1251-1274, July 2025.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni   +5 more
wiley   +1 more source

Recent advances in proteomic workflows to interrogate the SUMOylome in plants

open access: yesNew Phytologist, Volume 247, Issue 1, Page 90-96, July 2025.
Summary Protein posttranslational modifications (PTMs) are vital for regulating protein functions. SUMOylation, a PTM essential for plant survival, involves attaching a Small Ubiquitin‐like MOdifier (SUMO) to lysine residues of target proteins. SUMOylation influences stress tolerance, cell proliferation, protein stability, and gene expression.
Kishor D. Ingole   +3 more
wiley   +1 more source

Characterization and hepatoprotective evaluation of sesquiterpenes and diterpenes from the aerial parts of Juniperus sabina L.

open access: yesSaudi Pharmaceutical Journal, 2019
Previously, we reported on the hepatoprotective activity of the total extract of Juniperus sabina L. against CCl4 induced liver toxicity in experimental animals.
Maged S. Abdel-Kader   +6 more
doaj  

Alloying Engineering of Defective Molybdenum Sulfide Basal Planes for Enhanced Borrowing Hydrogen Activity in the Thioetherification of Alcohols

open access: yesChemSusChem, Volume 18, Issue 11, June 2, 2025.
Tungsten alloying makes the difference: The synthesis of thioethers from readily available alcohols and thiols is achieved by a borrowing‐hydrogen methodology applying alloyed molybdenum and tungsten sulfide catalysts engineered from molecular cluster complexes.
Miriam Rodenes   +5 more
wiley   +1 more source

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